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Zollinger-ellison syndrome
Zollinger-ellison syndrome A group of symptoms that occur when a tumor called a gastrinoma forms in the pancreas. The tumor, which may cause cancer, releases large amounts of the hormone gastrin. The gastrin causes too much acid in the duodenum, resulting in ulcers, bleeding, and perforation.
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Tumor Overgrowth of tissue.
Pancreas A large, elongated gland located behind the lower portion of the stomach that secretes the hormones insulin and glucagon into the blood. These hormones are essential in regulating blood sugar levels. The pancreas also secretes enzymes into the small intestine that help with digestion and neutralize acid from the stomach.
Cancer Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
Hormone A chemical substance formed in the body that is carried in the bloodstream to affect another part of the body; an example is thyroid hormone, produced by the thyroid gland in the neck, which affects growth, temperature regulation, metabolic rate, and other body functions.
Gastrin A hormone released after eating, which causes the stomach to produce more acid.
Duodenum The first part of the small intestine.
Perforation A hole or break through a membrane or the wall of an organ.
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