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Von Willebrand's Disease
Von Willebrand's Disease Von Willebrand's disease (vWD) is the most common hereditary coagulation abnormality described in humans. It arises from a qualitative or quantitative deficiency of von Willebrand factor (vWF), a multimeric protein that is required for platelet adhesion. It is known to affect humans and, in veterinary medicine, dogs.
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Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Hereditary
Transmitted from parent to offspring; derived from ancestry.
Coagulation
In medicine, the clotting of blood. The process by which the blood clots to form solid masses, or clots.
Protein
Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others.
Platelet
Small, irregularly-shaped bodies in the blood that contain granules. These cells are important components of the blood coagulation (clotting) system.
Adhesion
A band of scar tissue that joins normally separated internal body structures, most often after surgery, inflammation, or injury in the area.
Affect
This word is used to described observable behavior that represents the expression of a subjectively experienced feeling state (emotion). Common examples of affect are sadness, fear, joy, and anger. The normal range of expressed affect varies considerably between different cultures and even within the same culture. Types of affect include: euthymic, irritable, constricted; blunted; flat; inappropriate, and labile.
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Vitiligo
An autoimmune skin disorder caused by attack of the immune system on the pigment-producing cells within the skin. The loss of the cells responsible for skin color result in milky white patches on the skin surface.
Varicose Veins
Varicose veins -swollen, purple veins- are common in the legs and around the vaginal opening during late pregnancy. In most cases, varicose veins are caused by the increased pressure on the legs and the pelvic veins, and by the increased blood volume.
Vasopressin
Hormone secreted by the posterior pituitary gland (trade name Pitressin) and also by nerve endings in the hypothalamus; affects blood pressure by stimulating capillary muscles and reduces urine flow by affecting reabsorption of water by kidney tubules.
Vasoconstriction
A reduction in the diameter of small arteries (arterioles) which is caused by constriction of the smooth muscle fibres in the wall of the arteriole. Vasoconstriction is an important method of increasing the blood pressure. In local areas of damage it prevents blood loss by haemostasis. Local vasoconstriction can be caused by nerve impulses to the smooth muscle from the sympathetic nervous system, by locally released prostaglandins, serotonin and Epinephrine.
Von Willebrand's Disease
Veterinary Medicine
Veterinary medicine is the application of medical diagnostic and therapeutic principles to companion, domestic, exotic, wildlife, and production animals.
Viagra
A substance that is used to treat erectile dysfunction. Viagra relaxes the smooth muscle of the penis to allow increased blood flow and erection. It belongs to the family of drugs called phosphodiesterase inhibitors. Also called sildenafil.
Virility
The property of being capable of copulation and procreation.
Vicodin
Hydrocodone (chemical synonym: dihydrocodeinone; trade names: Vicodin, Anexsia, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Tussionex) is an opioid derived from either of the natural occuring opiates -- codeine or thebaine. Hydrocodone is an orally active analgesic and antitussive Schedule II narcotic which is marketed in multi-ingredient Schedule III products. The therapeutic dose of 5 mg to 10 mg is pharmacologically equivalent to 30 to 60 mg of oral codeine.
Veneer
Plastic or porcelain facing bonded directly to a tooth to improve its appearance. See laminate.
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