Variolation
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  Variolation



Variolation

   The historical practice of inducing immunity against smallpox by "scratching" the skin with the purulency from smallpox skin pustules. The first inoculation for smallpox is said to have been done in China about 1022 B.C.

RELATED TERMS
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Immunity
When a body's immune system helps fend off disease.

Smallpox
A viral disease that was once highly contagious. Characterized by high fever, vomiting, and blisters and sores on the skin. Vaccination has eliminated this disease.

Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).

Inoculation
The injection of a disease agent into the body to cause a mild form of the disease and build immunity.



SIMILAR TERMS
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Variance (statistics)
A measure of the amount by which a value differs from the mean.

Variant Angina
A type of angina that occurs at rest. Most often due to coronary spasm.

Varicella
Also known as chickenpox is a mild, highly contagious disease characterised by fever and itchy blisters all over the body. It is caused by the varicella zoster virus. It is very common in children but can affect people of all ages.

Varicella vaccine
The newest vaccine developed for children; the American Academy of Pediatrics recommends giving it between 12 and 14 months. Estimated to be 70 to 90 percent effective - if your child still comes down with chicken pox, it will be a mild case.

Varices
Stretched veins such as those that form in the esophagus from cirrhosis.

Varicocele
Dilated veins in the spermatic cord above or around the testis that can cause decreased sperm production on the affected side.

Varicose vein
An abnormally dilated vein.

Varicose Veins
Varicose veins -swollen, purple veins- are common in the legs and around the vaginal opening during late pregnancy. In most cases, varicose veins are caused by the increased pressure on the legs and the pelvic veins, and by the increased blood volume.

Varicose veins
Swollen, distended veins especially visible in the legs.

Variola
Syn: smallpox.



PREVIOUS AND NEXT TERMS
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Viscera
The large internal organs.

Vision
The sense of sight.

Vascularity
The blood supply of a tumor.

Vaccinia
An infection, primarily local and limited to the site of inoculation, induced in man by inoculation with the vaccinia (coxpox) virus in order to confer resistance to smallpox (variola). On about the third day after vaccination, papules form at the site of inoculation which become transformed into umbilicated vesicles and later pustules; they then dry up, and the scab falls off on about the 21st day, leaving a pitted scar; in some cases there are more or less marked constitutional disturbances.

Variola
Syn: smallpox.

Variolation

Viremia
The presence of virus in the bloodstream.

Virion
The complete virus particle that is structurally intact and infectious.

Vermiculite
A lightweight and highly water-absorbent micaceous mineral that is sometimes used as a substitute for asbestos.

Validation of data
Procedure carried out to ensure that the data contained in the final clinical trial report match original observations.

Validity
The accuracy of the relationship between two or more variables.

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