Telophase
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  Telophase



Telophase

    The final stage of mitosis in which the chromosomes migrate to opposite poles, a new nuclear envelope forms, and the chromosomes uncoil. The last phase of nuclear division in eukaryotes when the segregated chromosomes uncoil and begin to reform nuclei. This is immediately followed (in most cases) by cytokinesis.

RELATED TERMS
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Mitosis
The division of the cell's nucleus and nuclear material of a cell; consists of four stages: prophase, metaphase, anaphase, and telophase. Mitosis occurs only in eukaryotes. The DNA of the cell is replicated during interphase of the cell cycle and then segregated during the four phases of mitosis.

Chromosomes
Filaments of genetic material in every cell nucleus that are made up of genes and that transmit genetic information from one generation of cells to the next.

Nuclei
See nucleus.



SIMILAR TERMS
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Telogen effluvium
Thinning hair. Rarely results in actual baldness.

Telomer
A small segment at the end of nuclear DNA that becomes shorter with every replication of the DNA. DNA will no longer replicate beyond a certain point of telomere reduction.

Telomerase
An enzyme composed of a catalytic protein component and an RNA template and that synthesizes the telomeric DNA at the ends of chromosomes. When active, telomerase can continually add to the length of the telomeres on the ends of chromosomes within a cell, thus conferring on that cell the ability to continue dividing past its normal lifespan.

Telomeres
"Caps" (made of repeated DNA sequences) found at the ends of chromosomes that protect the ends of the chromosomes from degradation. The telomeres on a chromosome shorten with each round of cell replication. Telomere shortening has been suggested to be a "clock" that regulates how many times an individual cell can divide (that is, when the telomeres of the chromosomes in a cell shorten past a particular point, the cell can no longer divide).



PREVIOUS AND NEXT TERMS
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Thalassemia
An inherited disorder in which abnormal hemoglobin is formed; required repeated blood transfusions result in iron loading with especial impairment of functions of pituitary, heart and pancreas; prevalent in countries bordering the Mediterranean, in the Middle East, and in India and Southeast Asia.

Talus
Most superior bone of the foot that provides the primary connection between the leg and the foot and that articulates with the calcaneus to make up the subtalar joint.

Tibia
The segment of the leg between the femur and the tarsus.

Tarsus
Upper ankle region, or parts corresponding to it.

Trophoblast
A granular protoplasmic body; a plastid, formed from , eventually surrounds the entire embryo; insert themselves between uterine epithelial cells, then spread along the epithelial surface of the basal lamina that underlies the endometrial epithelium to form a trophoplate.

Telophase

Testis
(plural testes). A male's testes are located in a pouch that hangs suspended outside his body. The testes produce testosterone and sperm.

Thyroid scan
Uses a radioactive substance to create an image of the thyroid as it is functioning.

Thyroxin (T4)
A hormone secreted by the thyroid gland which regulates metabolism.

Triiodothyronine (T3)
A hormone secreted by the thyroid gland which regulates metabolism; exerts the same biological effects as thyroxine, but is generally more potent and the onset of its effect is more rapid.

Type 1 Diabetes
A condition in which the body's immune system destroys the cells in the pancreas that produce insulin. Insulin allows glucose to enter the cells of the body to provide energy. Persons with type 1 diabetes must take daily insulin injections.

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