Tay-Sachs disease
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  Tay-Sachs disease



Tay-Sachs disease

    A genetic disorder carried by an estimated one in 30 Eastern European Jews; babies born with Tay-Sachs lack an essential enzyme and die in early childhood. A preconception test can determine whether potential parents are carriers of the disease.

RELATED TERMS
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Genetic
Hereditary. Having to do with the genes.

Essential
1. Something that cannot be done without. 2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid. 3. Idiopathic. As in essential hypertension.

Enzyme
A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst.

Childhood
1. The time for a boy or girl from birth until he or she is an adult. 2. The more circumscribed period of time from infancy to the onset of puberty.

Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Totipotent cells
Stem cells that have unlimited developmental capability. The totipotent cells of the very early embryo (an embryo prior to the blastocyst stage) have the capacity to differentiate into extraembryonic tissues, membranes, the embryo, and all postembryonic tissues and organs.

Transcription
Making an RNA copy from a gene or other DNA sequence. Transcription is the first step in gene expression.

Transformation
A genetic process resulting in a heritable alteration of the properties of a cell. In the case of cultured cells, transformation often refers to the acquisition of new properties, such as unlimited culture lifespan.

Translation
The process of forming a protein molecule from information contained in messenger RNA.

Trophectoderm
The outer layer of the developing blastocyst that will ultimately form the embryonic side of the placenta.

Tay-Sachs disease

Teacher-to-child ratio
The number of caregivers per child in a group childcare setting. According to the National Association for the Education of Young Children, the lower the ratio, the better: A lower ratio means each child gets more attention and individual care.

Terbutaline
One of a family of medications called tocolytics, used to halt the contractions of preterm labor.

Testes
The pair of male glands, contained in the scrotum, that produce sperm.

Testicular torsion
Where the testicle twists inside the scrotum, usually because of an injury to the scrotum; can lead to infertility.

Thrombophlebitis
The inflammation of a vein associated with a blood clot.

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