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Prospective study
Prospective study Investigation in which a group of subjects is recruited and monitored in accordance with criteria described in a protocol.
RELATED TERMS--------------------------------------
Protocol
An outline of care; a treatment plan.
SIMILAR TERMS--------------------------------------
Proscar
Proscar is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): finasteride.
Prosol 20 per cent sulfite free in plastic container
Prosol 20 per cent sulfite free in plastic container is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): amino acids.
Prosom
Prosom is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): estazolam.
Prosopagnosia
A loss of the ability to identify members of complex categories such as faces.
Prosser Memorial Hospital
The Prosser Memorial Hospital is a hospital in Prosser, Washington, United States.
Prostaglandins
Molecules produced by the breakdown of arachidonic acid (from cell membranes) by cyclo-oxygenase. Most are inflammatory but some suppress inflammation.
Prostaphlin
Prostaphlin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): oxacillin sodium.
Prostascint
Prostascint is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): capromab pendetide.
Prostatalgia
Pain in the prostate gland.
Prostate
A male sex gland that produces a thick fluid which forms part of semen.
Prostate acid phosphatase (PAP)
An enzyme produced by the prostate that is elevated in some patients when prostate cancer has spread beyond the prostate.
Prostate cancer
A disease in which abnormal tumor cells develop in the prostate gland and may spread to other parts of the body, including the bones.
Prostate-specific antigen (PSA)
An antigen made by the prostate gland and found in the blood that may indicate cancer in the prostate gland.
Prostate-specific antigen blood test
A blood test used to help detect prostate cancer by measuring a substance called prostate-specific antigen made by the prostate.
Prostatism
Any condition of the prostate that causes interference with the flow of urine from the bladder.
Prostatitis
An inflamed condition of the prostate gland that may be accompanied by discomfort, pain, frequent urination, infrequent urination and sometimes fever.
Prostep
Prostep is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): nicotine.
Prosthesis
An artificial appliance for the replacement for a body part.
Prosthetic testis
An artificial testis made of a soft silicone compound and surgically implanted for cosmetic effect into an empty scrotum.
Prosthetics
The field of knowledge relating to prostheses.
Prosthodontist
Dental specialist skilled in restoring or replacing teeth with fixed or removable prosthesis (appliance), maintaining proper occlusion; treats facial deformities with artificial prostheses such as eyes, ears, and noses.
Prostin e2
Prostin e2 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): dinoprostone.
Prostin f2 alpha
Prostin f2 alpha is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): dinoprost tromethamine.
Prostin vr pediatric
Prostin vr pediatric is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): alprostadil.
Prostration
A marked loss of strength, as in exhaustion.
PREVIOUS AND NEXT TERMS--------------------------------------
Phases of clinical trials
Clinical trials are generally categorised into four (sometimes five) phases. An investigational medicine or product may be evaluated in two or more phases simultaneously in different trials, and some trials may overlap two different phases.
Phase 2a studies
Pilot clinical trials to evaluate efficacy and safety in selected populations of about 100 to 300 patients who have the disease or condition to be treated, diagnosed, or prevented. Often involve hospitalised patients who can be closely monitored. Objectives may focus on dose-response, type of patient, frequency of dosing, or any of a number of other issues involved in safety and efficacy.
Phase 3 studies
Multicentre studies in populations of perhaps 1000 to 3000 patients (or more) for whom the medicine is eventually intended. Phase 3 trials generate additional safety and efficacy data from relatively large numbers of patients in both controlled and uncontrolled designs and are used to support a PLA. Trials are also conducted in special groups of patients or under special conditions dictated by the nature of a particular medicine and/or disease. Phase 3 trials often provide much of the information needed for the package insert and labelling of the medicine.
Phase 5 studies
Postmarketing surveillance is sometimes referred to as Phase 5.
Postmarketing surveillance
ongoing safety monitoring of marketed drugs. See Phase 4 studies, Phase 5 studies.
Prospective study
Protocol amendment
A written description of a change(s) to or formal clarification of a protocol.
Pulmonary embolism
Blockage of one or more of the pulmonary arteries by a blood clot.
Psychokinesis (PK, cryptokinesis, telekinesis, telergy)
Alleged production or control of motion, or influencing of an event, mentally, without the use of bodily mechanisms. The word "telekinesis" implies involvement of the occult.
Psychospiritual
Pertaining to mental health and spirituality.
Psychotherapy (psychotherapeutics, therapy)
Treatment of illness--particularly mental and emotional disorders--or "adjustment" problems mainly with psychological techniques. Its major categories are individual psychotherapy and group psychotherapy. Psychotherapy ranges from specialistic therapy to informal conversations, and from science-oriented techniques (e.g., rational-emotive therapy [RET]) to quackery, applied pop psychology, religious counseling, and methods akin to mesmerism. Psychotherapists include clinical psychologists, clinical social workers, "counselors," psychiatric nurses, and psychiatrists.
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