Objective measurement A measurement that cannot be influenced by investigator bias; for example, blood glucose levels or ECG tracings.
A person responsible for the conduct of the clinical trial at a trial site. If a trial is conducted by a team of individuals at a trial site, the Investigator is the responsible leader of the team and may be called the Principal Investigator.
1. When a point of view prevents impartial judgment on issues relating to the subject of that point of view. In a clinical trial, bias refers to effects that a conclusion that may be incorrect as, for example, when a researcher or patient knows what treatment is being given. To avoid bias, a blinded study may be done. 2. Deviation of results or inferences from the truth, or processes leading to such systematic deviation. Any trend in the collection, analysis, interpretation, publication, or review of data that can lead to conclusions that are systematically different from the truth.
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.
The only simple carbohydrate that circulates in the bloodstream. Glucose is the primary fuel used by the brain. It can also be stored in the liver and muscles in a polymer form known as glycogen.
Object centered coordinate system
A structural description of an object independent of viewpoint.
A cognitive milestone, usually reached in the second or third year, when achild is able to understand that an object exists even when it's out ofview.
The emotional bonds between one person and another, as contrasted with interest in and love for the self; usually described in terms of capacity for loving and reacting appropriately to others. Melanie Klein is generally credited with founding the British object-relations school.
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A chemical element essential for sustaining life.
A device with a fluid reservoir implanted under the scalp with a catheter to a ventricle. It allows for medication to be given directly to the CSF and into the brain.
Fragments of genetic material (DNA) that carry the potential to cause cancer (transform normal cells into malignant cells).
The causation or production of tumors.
An individual trained to help people manage the daily activities of living, such as dressing, grooming or cooking, and regaining vocational skills.
A trial in which subjects and investigators know which product each subject is receiving; opposite of doubleblind study.
Original medical record
See source documents.
A general medical clinic focused.
Oriental Medical Doctor. ("D.O.M." stands for "Doctor of Oriental Medicine.")
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