Motor Neurone Disease
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  Motor Neurone Disease



Motor Neurone Disease

    Motor Neurone Disease (MND) is a term used to cover a number of illnesses of the motor neurone. Amyotrophic Lateral Sclerosis (ALS), Progressive Muscular Atrophy (PMA), Progressive Bulbar Palsy (PBP) and Progressive Lateral Sclerosis (PLS) are all types of MND. MND is the term used internationally while ALS is often used in the United States (where it is also known as Lou Gehrig's disease) to cover all forms of MND. It was first described by Jean-Martin Charcot, a French neurologist, in 1869.

RELATED TERMS
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Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Lateral
Toward the side, sideways.

Sclerosis
Hardening.

Atrophy
A defect or failure of cell nutrition manifested as decrease in size or healthiness of an organ or tissue.

Bulbar
Pertaining to a bulb, in medicine any rounded mass of tissue (that is shaped somewhat like a crocus or tulip bulb).

Palsy
Paralysis of a muscle or group of muscles

Neurologist
A physician who specializes in diagnosing and treating disorders of thenervous system, including the brain, spinal cord, nerves, and nerve centers.



SIMILAR TERMS
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Motofen
Motofen is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): atropine sulfate; difenoxin hydrochloride.

Motofen half-strength
Motofen half-strength is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): atropine sulfate; difenoxin hydrochloride.

Motor fusion
Changing the vergence of the two eyes so that images that fall on different points in the two retinas come to fall upon corresponding places in the central retinas. As opposed to Sensory Fusion.

Motor neuron disease
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In amyotrophic lateral sclerosis there is involvment of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy, the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation.

Motor skills
Motions carried out by the combination of the brain, nervous system, and muscles.



PREVIOUS AND NEXT TERMS
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Metabolism
The chemical activity that occurs in cells, releasing energy from nutrients, or using energy to create other substances, such as proteins.

Macrolide
A group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, are attached. The lactone ring can be either 14, 15 or 16-membered. Macrolides belong to the polyketide class of natural products.

Minocycline
Minocycline hydrochloride, also known as minocycline, is an antibiotic of the tetracycline class. It is marketed under several trade names, including Minomycin, and Dynacin. It is primarily used to treat acne.

Medical alarm
An electronic device used to call for help by pressing a medical alarm panic button, a wrist medical alert watch or medical alert necklace or pendant. A medical alarm system includes both hardware and a monitoring service.

Motor Neurone Disease

Metabolic Syndrome (MS)
A combination of health conditions that place a person at high risk for heart disease. These conditions are type 2 diabetes, hypertension (high blood pressure), hyperlipidemia (high levels of fat in the blood), and obesity. According to theory, all of these conditions are associated with high blood insulin levels, and it is claimed that the underlying problem in patients with the Metabolic Syndrome is faulty insulin release from the beta cells of the pancreas. Previously called Syndrome X.

Marfan Syndrome
Disorder of the connective tissue, affecting the heart and blood vessels, skeletal system, eyes, and other parts of the body. The condition is present at birth. Symptoms vary from person to person, ranging from mild to severe. People with Marfan syndrome are often nearsighted (see myopia), and about half have dislocation of one or both lenses of the eye. There is no cure for Marfan syndrome. Treatment depends on which body systems are affected. Early eye examinations can detect vision problems related to the disorder, which can usually be corrected with eyeglasses or contact lenses.

Myelodysplastic Syndrome
A group of neoplasms that originate in a primitive multipotential hematopoietic cell.. About half of the cases are mild to moderate anemias accompanied by mild to moderately reduced white cell and platelet counts. Often, these are not progressive but they have a heightened propensity to evolve into acute myelogenous leukemia. The other half of the cases are a type of low blast count leukemia that may be associated with severe white cell and platelet deficits. Many of the patients affected require transfusion therapy, have a propensity to infection or to bleeding, and frequently progress to more overt leukemia.

Morning after pill
The morning-after pill, also known as emergency contraception or emergency birth control, is a pill regimen that a woman can take up to three days after she has had sexual intercourse to prevent the implantation of a fertilized egg in her uterus. The term morning-after pill is a misnomer that is falling out of use (replaced by emergency contraceptive pills or ECPs) due to the fact that it is effective for up to 120 hours after sex.

Microcomedo
The first stage of comedo formation; a comedo so small that it can be seen only with a microscope.

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