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Minor histocompatibility antigens
Minor histocompatibility antigens These antigens, encoded outside the MHC, are numerous, but do not generate rapid graft rejection or primary responses of T cells in vitro. They do not serve as restricting elements in cell interactions.
RELATED TERMS--------------------------------------
Antigens
Substances that cause an immune response in the body. The body "sees" the antigens as harmful or foreign. To fight them, the body produces antibodies, which attack and try to eliminate the antigens.
MHC
Major Histocompatibility Complex. Region of chromosome 6 where HLA antigens are encoded.
Graft
A piece of skin or other tissue used as a transplant.
Rejection
The process by which the body tries to get rid of a transplanted organ or tissue by producing antibodies. Immunosuppressive drugs help to prevent rejection.
Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.
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Minocycline
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Minocycline hcl
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Minodyl is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): minoxidil.
Minoo doctors
All doctors near Minoo, Japan. Doctors who can assist a patient in Minoo.
Minor H antigens
Or minor histocompatibility antigens. A group of proteins (in addition to those encoded by the major histocompatibility complex (MHC) that can cause transplant tissue rejection. Minor H antigens can cause tissue rejection even when donor and recipient are matched for MHC. Immune response to minor H antigens is far less potent than response to MHC-encoded proteins, so the rejection is a slower process.
Minoxidil
Minoxidil is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): minoxidil.
Minoxidil extra strength for men
Minoxidil extra strength for men is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): minoxidil.
Minoxidil for men
Minoxidil for men is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): minoxidil.
Minoxidil for women
Minoxidil for women is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): minoxidil.
PREVIOUS AND NEXT TERMS--------------------------------------
Memory
In the immune system, memory denotes an active state of immunity to a specific antigen, such that a second encounter with that antigen leads to a larger and more rapid response.
MHC class I molecule
A molecule encoded to genes of the MHC which participates in antigen presentation to cytotoxic T (CD8+) cells.
MHC class II molecule
A molecule encoded by genes of the MHC which participates in antigen presentation to helper T (CD4+) cells.
MHC restriction
The ability of T lymphocytes to respond only when they 'see' the appropriate antigen in association with "self" MHC class I or class II proteins on the antigen presenting cells.
Migration inhibition factor (MIF)
A lymphokine that inhibits the motility of macrophages in culture.
Minor histocompatibility antigens
Mitogen
A substance that stimulates the proliferation of many different clones of lymphocytes.
Mixed lymphocyte reaction (MLR)
When lymphocytes from two individuals are cultured together, a proliferative response is generally observed, as the result of reactions of T cells of one individual to MHC antigens on the other individual's cells.
Monoclonal
Literally, coming from a single clone. A clone is the progeny of a single cell. In immunology, monoclonal generally describes a preparation of antibody that is monogenous, or cells of a single specificity.
Monocyte
Large circulating white cell, 2-10% of total white cells, phagocytic, indented nucleus. Migrates to tissues, where it is known as a macrophage.
Monokines
Soluble substances secreted by monocytes, which have a variety of effects on other cells.
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