Kallmann's syndrome
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  Kallmann's syndrome



Kallmann's syndrome

    A condition characterized by pubertal failure, inactive testicles (or ovaries), failure of the pituitary gland to secrete gonadotropic hormones, and failure of the hypothalamus to stimulate the pituitary gland, in association with absence of the sense of smell secondary to defective olfactory function in the brain.

RELATED TERMS
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Condition
The term "condition" has a number of biomedical meanings including the following: 1.An unhealthy state, such as in "this is a progressive condition." 2.A state of fitness, such as "getting into condition." 3.Something that is essential to the occurrence of something else; essentially a "precondition." 4.As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Pituitary
The gland from which a number of hormones are released into the bloodstream. These hormones include growth hormone, ACTH, B-lipocortin (the precursor to B-endorphorin), FSH, LH, and TSH.

Gland
An organ that releases a chemical. Endocrine glands are ductless and secrete hormones directly into the bloodstream. Exocrine glands secrete externally, either through a tube or duct.

Secrete
To make and give off such as when the beta cells make insulin and then release it into the blood so that the other cells in the body can use it to turn glucose (sugar) into energy.

Hormones
Biological compounds that communicate information at a distance. Hormones require specific receptors to begin their biological action and use second messengers to initiate the cellular process that uses that information.

Hypothalamus
The portion of the brain's limbic system that integrates incoming information, and either increases or decreases the release of certain hormones that instruct the pituitary gland to release hormones.

Association
1. In dysmorphology (the study of birth defects), the nonrandom occurrence in two or more individuals of a pattern of multiple anomalies (birth defects) not known to be a malformation syndrome (such as Down syndrome), a malformation sequence (of events) or what is called a polytopic field defect (in which all of the defects are concentrated in one particular area of the body). An example of an association in dysmorphology is the VACTERL association of birth defects. 2. In genetics, the occurrence together of two or more characteristics more often than would be expected by chance alone. An example of association involves a feature on the surface of white blood cells called HLA (HLA stands for human leukocyte antigen). A particular HLA type, HLA type B-27, is associated with an increased risk for a number of diseases including ankylosing spondylitis. The extent of the association is enormous. Ankylosing spondylitis is 87 times more likely to occur in people with HLA B-27 than in the general population.

Olfactory
Having to do with the sense of smell.

Brain
"That part of the central nervous system that is located within the cranium (skull). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called ""hemispheres."" "



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Keratitis
An inflammation of the cornea often caused by a virus or bacteria. Scarring and loss of vision may result.

Keratoconus
An inherited disease where the cornea becomes progressively shaped like a cone. Wearing a contact lens may slow the progression of the disease. Corneal transplant surgery may be required.

Keratoplasty
A corneal transplant.

K cell
An effector lymphocyte with Fc receptors which allow it to bind to and kill antibody-coated target cells.

Killer T cell
A T cell with a particular immune specificity and an endogenously produced receptor for antigen, capable of specifically killing its target cell after attachment to the target cell by this receptor. Also called cytotoxic T cell.

Kallmann's syndrome

Keloid
A ridge or lump of progressively enlarging scar tissue due to the accumulation of excessive amounts of collagen during the healing of a wound. The possibility of keloid formation is positively correlated with skin pigmentation.

Kinesis
Body movement and activity.

Kleptolagnia
Sexuoerotic gratification produced by stealing [from Greek, kleptein, to steal + lagneia, lust].

Kleptomania
Compulsive stealing, usually of objects that have symbolic significance but not intrinsic value to the thief [from Greek, kleptein, to steal + mania, madness].

Klismaphilia
A paraphilia of the fetishistic/talismanic type in which sexuoerotic arousal and facilitation or attainment of orgasm are responsive to and [dependent upon]{contingent on} being given an enema by the partner [from Greek, klysma, enema + -philia] There is no technical term for the reciprocal paraphilic condition, namely of being the enema giver. Klismaphilia may be adjunctive to rubber fetishism or to bondage and discipline. (adjective, klismaphilic): the condition in which a person is dependent on being given an enema, or on the restaging of it in fantasy, in order to obtain erotic arousal and facilitate or achieve orgasm.

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