Ichthyoses
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  Ichthyoses



Ichthyoses

   Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.

RELATED TERMS
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Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).

Hypertrophy
Over-development in size of an organ or of its constituent cells.

Epidermis
The outermost layer of skin.

Genetic
Hereditary. Having to do with the genes.

Acquired
"Anything that is not present at birth but develops some time later. In medicine, the word ""acquired"" implies ""new"" or ""added."" An acquired condition is ""new"" in the sense that it is not genetic (inherited) and ""added"" in the sense that was not present at birth. For example, AIDS (the acquired immune deficiency syndrome) is an acquired form of immune deficiency due to the acquisition of HIV (the human immunodeficiency virus). An acquired mutation is a change in a gene that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer."

Association
1. In dysmorphology (the study of birth defects), the nonrandom occurrence in two or more individuals of a pattern of multiple anomalies (birth defects) not known to be a malformation syndrome (such as Down syndrome), a malformation sequence (of events) or what is called a polytopic field defect (in which all of the defects are concentrated in one particular area of the body). An example of an association in dysmorphology is the VACTERL association of birth defects. 2. In genetics, the occurrence together of two or more characteristics more often than would be expected by chance alone. An example of association involves a feature on the surface of white blood cells called HLA (HLA stands for human leukocyte antigen). A particular HLA type, HLA type B-27, is associated with an increased risk for a number of diseases including ankylosing spondylitis. The extent of the association is enormous. Ankylosing spondylitis is 87 times more likely to occur in people with HLA B-27 than in the general population.

Systemic
Disease or symptoms that affect many different parts of the body.

Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Syndrome
A grouping of signs and symptoms, based on their frequent co-occurrence, that may suggest a common underlying pathogenesis, course, familial pattern, or treatment selection.



SIMILAR TERMS
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Ichthyoses, Harlequin
A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.

Ichthyoses, Lamellar
A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.

Ichthyoses, Sex-Linked
Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the X-chromosome and transmitted to the male offspring. It is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.

Ichthyoses, X-Linked
Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the X-chromosome and transmitted to the male offspring. It is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.

Ichthyosiform Erythroderma, Bullous Congenital
A form of congenital ichthyosis inherited as an autosomal dominant trait and characterized by erythroderma and severe hyperkeratosis. It is manifested at birth by blisters followed by the appearance of thickened, horny, verruciform scales over the entire body, but accentuated in flexural areas.

Ichthyosiform Erythroderma, Congenital
Designation for several severe forms of ichthyosis, present at birth, that are characterized by hyperkeratotic scaling. Infants may be born encased in a collodion membrane which begins shedding within 24 hours. This is followed in about two weeks by persistent generalized scaling. The forms include bullous (HYPERKERATOSIS, EPIDERMOLYTIC), non-bullous (ICHTHYOSIS, LAMELLAR), wet type, and dry type.

Ichthyosiform Erythroderma, Nonbullous Congenital
A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.

Ichthyosiform Erythrodermas, Congenital
Designation for several severe forms of ichthyosis, present at birth, that are characterized by hyperkeratotic scaling. Infants may be born encased in a collodion membrane which begins shedding within 24 hours. This is followed in about two weeks by persistent generalized scaling. The forms include bullous (HYPERKERATOSIS, EPIDERMOLYTIC), non-bullous (ICHTHYOSIS, LAMELLAR), wet type, and dry type.

Ichthyosis
An inherited skin disorder that produces dry, rough, scaly skin.

Ichthyosis Vulgaris
Most common form of ICHTHYOSIS characterized by prominent scaling especially on the exterior surfaces of the extremities. It is inherited as an autosomal dominant trait.

Ichthyosis Vulgaris, Dominant
Most common form of ICHTHYOSIS characterized by prominent scaling especially on the exterior surfaces of the extremities. It is inherited as an autosomal dominant trait.

Ichthyosis, Harlequin
A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.

Ichthyosis, Lamellar
A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.

Ichthyosis, Sex Linked
Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the X-chromosome and transmitted to the male offspring. It is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.

Ichthyosis, Sex-Linked
Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the X-chromosome and transmitted to the male offspring. It is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.

Ichthyosis, X Linked
Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the X-chromosome and transmitted to the male offspring. It is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.

Ichthyosis, X-Linked
Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the X-chromosome and transmitted to the male offspring. It is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.



PREVIOUS AND NEXT TERMS
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Ibuprofen, (+-)-Isomer
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen Zinc
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen I.V. Solution
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibumetin
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ichthyoses, Harlequin
A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.

Ichthyoses

Icelandic Type Hereditary Cerebral Amyloid Angiopathy
A familial condition marked by the deposition of AMYLOID in the walls of small blood vessels in the cerebral cortex and meninges and characterized clinically by cerebral ischemia (see BRAIN ISCHEMIA), CEREBRAL INFARCTION, and CEREBRAL HEMORRHAGE..

Icelandic Type Amyloidosis
A familial condition marked by the deposition of AMYLOID in the walls of small blood vessels in the cerebral cortex and meninges and characterized clinically by cerebral ischemia (see BRAIN ISCHEMIA), CEREBRAL INFARCTION, and CEREBRAL HEMORRHAGE..

Ice Skatings
Using ice skates, roller skates, or skateboards in racing or other competition or for recreation.

Ice, Dry
A solid form of carbon dioxide used as a refrigerant.

Ice Skating
Using ice skates, roller skates, or skateboards in racing or other competition or for recreation.

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