IC50
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  IC50



IC50

   The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.

RELATED TERMS
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Concentration
Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.

Eukaryotic
The living world is divided into two classes of organism. Eukaryotic and, much simpler, prokaryotic organisms such as bacteria. Generally eukaryotes are diploid and their cells have internal organelles, such as nuclei. Prokaryotes are haploid with much simpler cells.

Antibacterial
Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Culture
Growth of cells, tissues or embryos in vitro on an artificial nutrient medium in the laboratory.



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Ibuprofen, Sodium Salt
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen, Magnesium Salt
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen, Copper (2+) Salt
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen, Calcium Salt
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

ICAM-1
A cell-surface ligand with a role in leukocyte adhesion and inflammation. Its production is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue.

IC50

IC3b
The larger fragment formed when C3 convertase splits C3 into C3a and C3b. In both the classical and alternate pathway, C3b participates in immune adherence and enhances phagocytosis. It also forms a cellular intermediate which continues the complement process. In the alternate pathways, C3b initiates a positive feedback activation of C3Pase.

Ibuprofen-Zinc
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen, Zinc Salt
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen, Aluminum Salt
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

Ibuprofen, (S)-Isomer
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.

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   c50 / i50 / ic0 / ic5 / iic50 / icc50 / ic550 / ic500 / c50 / ix50 / is50 / id50 / if50 / iv50 / i 50 / ic60 / icy0 / ict0 / icr0 / ic40 / ic5- / ic5[ / ic5p / ic5o / ic59 /