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Histocompatibility
Histocompatibility Literally, the ability of tissues to get along; in immunology, it means identity in all transplantation antigens. These antigens, in turn, are collectively referred to as histocompatibility antigens.
RELATED TERMS--------------------------------------
Immunology
The study of the body's natural defense system.
Transplantation
To transfer (tissue or an organ) from one body or body part to another.
Antigens
Substances that cause an immune response in the body. The body "sees" the antigens as harmful or foreign. To fight them, the body produces antibodies, which attack and try to eliminate the antigens.
Histocompatibility
Literally, the ability of tissues to get along; in immunology, it means identity in all transplantation antigens. These antigens, in turn, are collectively referred to as histocompatibility antigens.
SIMILAR TERMS--------------------------------------
Histafed
Histafed is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): pseudoephedrine hydrochloride; triprolidine hydrochloride.
Histalog
Histalog is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): betazole hydrochloride.
Histamine
A chemical present in cells throughout the body that is released during an allergic reaction and one of the substances responsible for the symptoms of inflammation.
Histamine phosphate
Histamine phosphate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): histamine phosphate.
Histiocyte
A large, phagocytic cell of the reticuloendothelial system; a macrophage.
Histiocytoma
A common neoplasm of young dogs composed of round histiocytic cells, thought to be Langerhan's cells. Most tumors spontaneously regress.
Histiocytosis-X
Includes eosinophilic granuloma, Hand-Schuller-Christian disease and Letterer-Siwe disease.
Histology
The study of the structure and behavior of cells and body tissues, usually involving microscopic examination of tissue slices.
Histoplasmosis
A fungal disease caused by inhaling the spores of Histoplasma capsulatum.
PREVIOUS AND NEXT TERMS--------------------------------------
Heavy chain
The larger of the two types of chains that comprise a normal immunoglobulin or antibody molecule.
H chain
The larger of the two types of chains that comprise a normal immunoglobulin or antibody molecule.
Helper T cells
A class of T cells which help trigger B cells to make antibody against thymus-dependent antigens. Helper T cells also help generate cytotoxic T cells.
Heterophile antigen
A cross-reacting antigen that appears in widely ranging species such as humans and bacteria.
Hinge region
A flexible, open segment of an antibody molecule that allows bending of the molecule. The hinge region is located between Fab and Fc and is susceptible to enzymatic cleavage.
Histocompatibility
Humoral immunity
Any immune reaction that can be transferred with immune serum is termed humoral immunity (as opposed to cell-mediated immunity). In general, this term refers to resistance that results from the presence of specific antibody.
Hybridoma
A hybrid cell that results from the fusion of an antibody-secreting cell with a malignant cell; the progeny secrete antibody without stimulation and proliferate continuously both in vivo and in vitro.
Hypersensitivity
State of reactivity to antigen that is greater than normal for the antigenic challenge; hypersensitivity is the same as allergy and denotes a deleterious outcome rather than a protective one.
Hypervariable regions
Portions of the light and heavy immunoglobulin chains that are highly variable in amino acid sequence from one immunoglobulin molecule to another, and that, together, constitute the antigen-binding site of an antibody molecule. Also, portions of the T-cell receptor which constitute the antigen-binding site.
Hallucinosis
A morbid condition, as in acute alcoholic hallucinosis, which is characterized by recurrent acute attacks marked by hallucinated auditory threats of persecution.
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