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Heterophile antigen
Heterophile antigen A cross-reacting antigen that appears in widely ranging species such as humans and bacteria.
RELATED TERMS--------------------------------------
Antigen
A substance which, when present in animal tissue, stimulates the production of antibodies
SIMILAR TERMS--------------------------------------
Heterocellular
Composed of more than one type of cell.
Heterogeneous
Dissimilar in type, and having different or opposing characteristics.
Heterologous
1. Pertaining to cytologic or histologic elements occurring where they are not normally found.2. Derived from an animal of a different species, as the serum of a horse is heterologous for a rabbit.
Heterophilia
The condition in which love and lust are attached to those of the other sex. A condition of being in which sexuoerotic arousal and facilitation or attainment of orgasm are responsive to, and dependent upon a partner of the other morphologic sex.
Heterophobia
The condition in which those whose love and lust are attached to persons of the other sex are dreaded or feared.
Heteroplasmy
An atypical condition characterized by the presence of more than one type of mitochondrial DNA in a single individual. Normally, each individual has only one type of mitochondrial DNA, inherited from his or her mother through the egg at fertilization. (Mitochondria from the sperm are systematically eliminated by the egg at fertilization.)
Heterosexual
Characterized by other-sex contact, either as a genital act or as a long-term sexuoerotic status. It is analogous to right-handedness in being in conformity with the norm and therefore is not pathological in itself, though subject to other pathology. A heterosexual person is able to fall in love with, and become the pairbonded sexuoerotic partner of only a person of the other morphologic sex. Paraphilias occur predominantly in association with heterosexual pairing. The ideation and affective state, exclusive of the behavioral component, is heterophilia.
Heterosexualism
Other-sex contact, either as a genital act or as a long term sexuoerotic status. It is analogous to right-handedness in being in conformity with the norm and, therefore, not pathological in itself, though subject to other pathology. A heterosexual person is able to fall in love with, and become the pairbonded sexuoerotic partner of only a person of the other morphologic sex. Paraphilias occur predominantly in association with heterosexual pairing.
Heterosexuality
Erotosexual pairing with a partner of the complementary genital morphology. It's full manifestation includes falling in love.
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Haplotype
A particular combination of closely linked genes on a chromosome inherited from one patient.
Hapten
A compound, usually of low molecular weight, that is not itself immunogenic but that, after conjugation to a carrier protein or cells, becomes immunogenic and induces antibody, which can bind the hapten alone in the absence of carrier.
Heavy chain
The larger of the two types of chains that comprise a normal immunoglobulin or antibody molecule.
H chain
The larger of the two types of chains that comprise a normal immunoglobulin or antibody molecule.
Helper T cells
A class of T cells which help trigger B cells to make antibody against thymus-dependent antigens. Helper T cells also help generate cytotoxic T cells.
Heterophile antigen
Hinge region
A flexible, open segment of an antibody molecule that allows bending of the molecule. The hinge region is located between Fab and Fc and is susceptible to enzymatic cleavage.
Histocompatibility
Literally, the ability of tissues to get along; in immunology, it means identity in all transplantation antigens. These antigens, in turn, are collectively referred to as histocompatibility antigens.
Humoral immunity
Any immune reaction that can be transferred with immune serum is termed humoral immunity (as opposed to cell-mediated immunity). In general, this term refers to resistance that results from the presence of specific antibody.
Hybridoma
A hybrid cell that results from the fusion of an antibody-secreting cell with a malignant cell; the progeny secrete antibody without stimulation and proliferate continuously both in vivo and in vitro.
Hypersensitivity
State of reactivity to antigen that is greater than normal for the antigenic challenge; hypersensitivity is the same as allergy and denotes a deleterious outcome rather than a protective one.
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