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Henoch-Schoenlein purpura
Henoch-Schoenlein purpura Anaphylactoid purpura. A form of allergic vasculitis. The features are arthritis, rash, gastrointestinal involvement and nephritis. Commoner in children.
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Purpura
A hemorraghic disease characterized by extravasation of blood into the tissues producing spontaneous ecchymoses and petechiae.
Vasculitis
Inflammation throughout the body of the blood vessels.
Arthritis
Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. Arthritis occurs in various forms, such as the arthritis associated with infections, osteoarthritis, or rheumatoid arthritis. Many forms of vasculitis can also be associated with arthritis.
Rash
A reddish spot or patch of irritated skin. Rashes can be caused byillnesses, allergies, and heat and are usually temporary.
Gastrointestinal
Having to do with the stomach and intestines.
Nephritis
Inflammation of a kidney.
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Hallux valgus
Devation of the big toe towards the out side of the foot. Osteoarthritis is one cause.
HSC disease
Hand-Schuller-Christian disease. A form of Histiocytosis-X.
Heat shock proteins
Produced in response to physiological stress. Of interest in inflammatory arthritis because antigenic.
Heberden's nodes
Bony swellings on distal interphalangeal joints (at the ends of the fingers) in osteoarthritis.
Hemiarthroplasty
Partial joint replacement - in the knee for example.
Henoch-Schoenlein purpura
Histiocytosis-X
Includes eosinophilic granuloma, Hand-Schuller-Christian disease and Letterer-Siwe disease.
HLA antigens
Human Leukocyte Antigens. (Histocompatibility antigens.) Detected by blood testing. An individual inherits a combination of HLA antigens from his or her parents. They are related to the working of the immune system. For instance, organ donors and recipients must have compatible HLA antigens, otherwise the transplanted organ is recognised as 'foreign'. Certain HLA antigens confer susceptibility to certain diseases and this explains the heritability of some diseases.
HLA B27
The histocompatibility antigen which is strongly associated with ankylosing spondylitis and other seronegative spondylarthritides. It occurs in 10% of the population and is detected using a blood test.
HLA DR4
HLA antigen associated with rheumatoid arthritis. The association is not as strong as in the case of HLA B27 and ankylosing spondylitis.
Hoffa's disease
Knee fad-pad syndrome. Pain and swelling underneath the patellar tendon.
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