Haemophilus influenzae Vaccines
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  Haemophilus influenzae Vaccines



Haemophilus influenzae Vaccines

   Vaccines or candidate vaccines containing antigenic polysaccharides from Haemophilus influenzae and designed to prevent infection. The vaccine can contain the polysaccharides alone or more frequently polysaccharides conjugated to carrier molecules. It is also seen as a combined vaccine with diphtheria-tetanus-pertussis vaccine.

RELATED TERMS
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Haemophilus
A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.

Infection
Anything that invades the body and reproduces. Infections can be bacteria, protozoa, fungi, or viruses. Bacteria and fungi are one celled creatures that cause many infections including strep throat, bladder infections, and some lung infections. Fungi cause “athlete’s foot” and thrush, an infection in the mouth. Protozoa are small organisms with many cells that can cause infections in the guts or in the lungs. Most healthy people do not get protozoal infections, but people with suppressed immune systems can. Viruses are not really organisms; they are tiny particles that can live only inside another cell. They reproduce by taking over a cell and causing that cell to make more virus particles, rather than doing what the cell is supposed to do. Viruses cause most colds and flu cases.

Vaccine
A preparation, often of living weakened microorganisms, that is introduced into the body to produce immunity to a specific disease by causing the formation of antibodies.

Carrier
A large immunogenic molecule or particle to which an antigenic determinant is attached, allowing the determinant to become immunogenic.



SIMILAR TERMS
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Haem Oxygenase
A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt. EC 1.14.99.3.

Haemaccel
A 3.5 per cent colloidal solution containing urea-cross-linked polymerized peptides. It has a molecular weight of approximately 35,000 and is prepared from gelatin and electrolytes. The polymeric solution is used as a plasma expander.

Haemachatus
A genus of poisonous snakes of the subfamily Elapinae of the family ELAPIDAE. There are six recognized species, all inhabiting Africa except the Asiatic (Indian) cobra, Naja naja. Some species ""spit"" their venom into the eyes of their ""enemies"". So-called spitting cobras show a high degree of accuracy in aiming for the eyes. The ringhals, the most highly specialized of the spitting cobras, is limited to southern Africa. Its spray destroys eye tissue and can cause blindness; its bite can cause death. (Moore: Poisonous Snakes of the World, 1980, p80)

Haematobia irritans
A family of the order DIPTERA with over 700 species. Important species that may be mechanical vectors of disease include Musca domesticus (HOUSEFLIES), Musca autumnalis (face fly), Stomoxys calcitrans (stable fly), Haematobia irritans (horn fly) and Fannia spp.

Haematopinus
An order of insects comprising the sucking lice, which are blood-sucking ectoparasites of mammals. Recognized families include: Echionphthiriidae, Haematopinidae, and Pediculidae. The latter contains the medically important genera affecting humans: PEDICULUS and PHTHIRUS.

Haematoporphyrin IX
Iron-free derivatives of heme with 4 methyl groups, 2 hydroxyethyl groups and 2 propionic acid groups attached to the pyrrole rings. Some of these PHOTOSENSITIZING AGENTS are used in the PHOTOTHERAPY of malignant NEOPLASMS.

Haematoxylon
A dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.

HaEmek Medical Center
The HaEmek Medical Center is a hospital in Afula, Israel.

Haemobartonella
A family of bacteria which inhabit red blood cells and cause several animal diseases.

Haemobartonelloses
Infections with bacteria of the family ANAPLASMATACEAE.

Haemobartonellosis
Infections with bacteria of the family ANAPLASMATACEAE.

Haemonchiases
Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.

Haemonchiasis
Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.

Haemonchus
A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental.

Haemophilus
A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.

Haemophilus aphrophilus Meningitides
BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS; SENSORINEURONAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)

Haemophilus aphrophilus Meningitis
BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS; SENSORINEURONAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)

Haemophilus ducreyi
A species of HAEMOPHILUS that appears to be the pathogen or causative agent of the sexually transmitted disease, CHANCROID.

Haemophilus Infection
Infections with bacteria of the genus HAEMOPHILUS.

Haemophilus Infections
Infections with bacteria of the genus HAEMOPHILUS.

Haemophilus influenzae
A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.

Haemophilus influenzae Meningitis Type B
BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS; SENSORINEURONAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)

Haemophilus influenzae type b
A type of H. influenzae isolated most frequently from biotype I. Prior to vaccine availability, it was a leading cause of childhood meningitis.

Haemophilus Meningitides
BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS; SENSORINEURONAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)

Haemophilus Meningitis
BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS; SENSORINEURONAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)

Haemophilus parainfluenzae Meningitides
BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS; SENSORINEURONAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)

Haemophilus parainfluenzae Meningitis
BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS; SENSORINEURONAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)

Haemophilus pertussis
A species of gram-negative, aerobic bacteria that is the causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that are surrounded by a slime sheath.

Haemophilus pleuropneumoniae
A species of gram-negative, facultatively anaerobic coccobacillus-shaped bacteria that has been isolated from pneumonic lesions and blood. It produces pneumonia with accompanying fibrinous pleuritis in swine.

Haemophilus Vaccine
Vaccines or candidate vaccines containing antigenic polysaccharides from Haemophilus influenzae and designed to prevent infection. The vaccine can contain the polysaccharides alone or more frequently polysaccharides conjugated to carrier molecules. It is also seen as a combined vaccine with diphtheria-tetanus-pertussis vaccine.

Haemophilus Vaccines
Vaccines or candidate vaccines containing antigenic polysaccharides from Haemophilus influenzae and designed to prevent infection. The vaccine can contain the polysaccharides alone or more frequently polysaccharides conjugated to carrier molecules. It is also seen as a combined vaccine with diphtheria-tetanus-pertussis vaccine.

Haemophilus vaginalis
The only species in the genus GARDNERELLA, and previously classed as Haemophilus vaginalis. This bacterium, also isolated from the female genital tract of healthy women, is implicated in the cause of bacterial vaginosis (VAGINOSIS, BACTERIAL). It occasionally causes postpartum bacteremia and bacteremia following a transurethral resection of the prostate.

Haemorrhagic Adrenalitis, Meningococcal
A condition characterized by the abrupt onset of fever, petechiae, ARTHRALGIA, weakness, and myalgias followed by acute hemorrhagic necrosis of the adrenal glands and severe cardiovascular dysfunction. The syndrome is most often associated with meningococcal septicemia but may occur as a complication of sepsis caused by other organisms, including certain STREPTOCOCCUS species. This disorder may be associated with a prior history of SPLENECTOMY. (From J Emerg Med 1998 Jul-Aug;16(4):643-7)

Haemorrhagic stroke
A stroke caused by intracerebral haemorrhage, or bleeding from a blood vessel within the brain. See also aneurysm.

Haemosporida
An order of heteroxenous protozoa in which the macrogamete and microgamont develop independently. A conoid is usually absent.

Haemosporina
An order of heteroxenous protozoa in which the macrogamete and microgamont develop independently. A conoid is usually absent.



PREVIOUS AND NEXT TERMS
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Harlequin Ichthyosis
A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.

Havrix
Vaccines or candidate vaccines used to prevent infection with hepatitis A virus (HEPATOVIRUS).

Haploidies
The number of chromosomes in the gametes, which is half the number normally found in somatic cells. Symbol: N.

Hairy Tongues
A benign condition of the tongue characterized by hypertrophy of the filiform papillae that give the dorsum of the tongue a furry appearance. The color of the elongated papillae varies from yellowish white to brown or black, depending upon staining by substances such as tobacco, food, or drugs. (Dorland, 27th ed)

Hallucinations, Verbal Auditory
Subjectively experienced sensations in the absence of an appropriate stimulus, but which are regarded by the individual as real. They may be of organic origin or associated with MENTAL DISORDERS.

Haemophilus influenzae Vaccines

Hagedorn Insulin, Protamine
A modified form of insulin that contains protamine and zinc. Isophane insulin is an intermediate-acting INSULIN with time of onset of 2 hours and duration of 24 hours.

Headache, Cervicogenic
Common conditions characterized by persistent or recurrent headaches (see HEADACHE). Headache syndrome classification systems may be based on etiology (e.g., VASCULAR HEADACHE, post-traumatic headaches, etc.), temporal pattern (e.g., CLUSTER HEADACHE, paroxysmal hemicrania, etc.), and precipitating factors (e.g., cough headache).

Headache, Bilateral
Pain in the cranial region that may occur as an isolated and benign symptom or as a manifestation of a wide variety of conditions including SUBARACHNOID HEMORRHAGE; CRANIOCEREBRAL TRAUMA; CENTRAL NERVOUS SYSTEM INFECTIONS; INTRACRANIAL HYPERTENSION; and other disorders. In general, recurrent headaches that are not associated with a primary disease process are referred to as HEADACHE DISORDERS (e.g., MIGRAINE).

Headache, Benign Exertional
Common conditions characterized by persistent or recurrent headaches (see HEADACHE). Headache syndrome classification systems may be based on etiology (e.g., VASCULAR HEADACHE, post-traumatic headaches, etc.), temporal pattern (e.g., CLUSTER HEADACHE, paroxysmal hemicrania, etc.), and precipitating factors (e.g., cough headache).

Headache, Atypical Cluster
A syndrome characterized by daily episodes of intense periorbital pain that recur over a period of 6-12 weeks that may be followed by a period of remission of months to years. The pain is non-throbbing, has a duration of 30-60 minutes and tends to occur at night or at regular intervals during the day. Unilateral rhinorrhea, conjunctival injection, lacrimation, facial flushing, and miosis frequently accompany the headaches, which primarily affect young adult males. (Adams et al., Principles of Neurology, 6th ed, p181)

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