Germ cell tumor
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  Germ cell tumor



Germ cell tumor

   A tumor that arise from a germ cell. These tumors may arise within the gonads -- the ovary and testis. Most testicular tumors are, in fact, germ cell tumors. Germ cell tumors also occur in sites outside the gonads, reflecting the fact that germ cells travel to diverse areas of the body, such as the chest, abdomen, and brain.

RELATED TERMS
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Tumor
Overgrowth of tissue.

Germ
A disease-causing microorganism.

Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.

Gonads
Ovaries and testes.

Ovary
The female sex gland that contains ova, or eggs.

Testis
(plural testes). A male's testes are located in a pouch that hangs suspended outside his body. The testes produce testosterone and sperm.

Chest
The area of the body located between the neck and the abdomen. The chest contains the lungs, the heart and part of the aorta. The walls of the chest are supported by the dorsal vertebrae, the ribs, and the sternum.

Abdomen
The area between the chest and the hips. Contains the stomach, small intestine, large intestine, liver, gallbladder, pancreas, and spleen.

Brain
"That part of the central nervous system that is located within the cranium (skull). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called ""hemispheres."" "



SIMILAR TERMS
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Germ
A disease-causing microorganism.

Germ cell
Or germline cell. A sperm or egg, or a cell that can develop into a sperm or egg; all other body cells are called somatic cells.

Germ line
Refers to genes in germ cells as opposed to somatic cells, that is, genes in their unrearranged state rather than those rearranged for production of a protein.

Germa-medica
Germa-medica is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hexachlorophene.

Germa-medica "mg"
Germa-medica "mg" is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hexachlorophene.

German doctor
A doctor who, being or not a citizen of that country, has been admitted to practice medicine in Germany.

German measles
See rubella.

German measles immunization
The standard MMR vaccine is given to prevent measles, mumps and rubella (German measles). The MMR vaccine is now given in two dosages. The first should be given at 12-15 months of age. The second vaccination should be given at 4-6 years. Most children should receive MMR vaccinations. Exceptions may include children born with an inability to fight off infection, some children with cancer, on treatment with radiation or drugs for cancer, on long term steroids (cortisone). People with severe allergic reactions to eggs or the drug neomycin should probably avoid the MMR vaccine. Pregnant women should wait until after delivery before being immunized with MMR. People with HIV or AIDS should normally receive MMR vaccine. Measles, mumps, and rubella vaccines may be administered as individual shots, if necessary, or as a measles- rubella combination.

German measles vaccine
A vaccine designed to prevent rubella, or German measles. The rubella vaccine has since been refined into the vaccine now known as MMR for mumps, measles and rubella. The congenital rubella syndrome is now largely a chapter in the history of medicine, thanks to the rubella vaccine.

Germanium
A nonessential trace element that has caused nephrotoxicity (kidney injury) and death when used chronically by humans, even at recommended levels of use.

Germantown Health Care Center
The Germantown Health Care Center is a hospital in Philadelphia, Pennsylvania, United States.

Germantown Hospital and Medical Center
The Germantown Hospital and Medical Center is a hospital in Philadelphia, Pennsylvania, United States.

Germantown Mediq Mri Center
The Germantown Mediq Mri Center is a hospital in Philadelphia, Pennsylvania, United States.

Germinal vesicle transfer
Or oocyte nuclear transfer. An assisted reproductive technique involving transfer of an egg nucleus (usually from a woman with age-related infertility or mitochondrial disease) into a healthy donor egg whose nucleus has been removed. This reconstituted egg can then be fertilized by a sperm in vitro. This technique may restore fertility to older women or to prevent the passing of mitochondrial disease to offspring.

Germinoma
A type of germ cell tumor.

Germiston doctors
All doctors near Germiston, South Africa. Doctors who can assist a patient in Germiston.

Germline cell
Or germ cell. A sperm or egg, or a cell that can develop into a sperm or egg; all other body cells are called somatic cells.

Germline mutation
A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single-cell stage. When transmitted to a child, a germline mutation is incorporated in every cell of their body. Germline mutations play a key role in genetic diseases. They play a role, too, in certain types of cancer as, for example, the eye tumor retinoblastoma and Wilms tumor, a childhood malignancy of the kidney. A germline mutation is in contrast to a somatic mutation which is acquired in a single body cell.



PREVIOUS AND NEXT TERMS
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Genotoxin
A poisonous substance which damages DNA. A genotoxin can cause mutations in DNA (and so be a mutagen), it can trigger cancer (and so be a carcinogen), or it can cause a birth defect (and so be a teratogen).

Genu
The Latin word for the knee. When the knee is referred to in medicine, it is just called the knee. However, the word "genu" is also used in medicine as in: genu recurvatum (hyperextension of the knee), genu valgum (knock knee) and genu varum (bowleg). The knee (or genu, if you are into Latin) is a joint which has three parts. The thigh bone (femur) meets the large shin bone (tibia) forming the main knee joint. This joint has an inner (medial) and an outer (lateral) compartment. The kneecap (patella) joins the femur to form a third joint, called the patellofemoral joint. The knee joint is surrounded by a joint capsule with ligaments strapping the inside and outside of the joint (collateral ligaments) as well as crossing within the joint (cruciate ligaments). These ligaments provide stability and strength to the knee joint.

Gephyrophobia
An abnormal and persistent fear of crossing bridges. Sufferers of this phobia experience undue anxiety even though they realize their fear is irrational. Their fear may result partly from the fear of enclosure (claustrophobia) or the fear of heights (acrophobia). Phobic drivers may worry about being in an accident in busy traffic or losing control of their vehicles. High bridges over waterways and gorges can be especially intimidating, as can be very long or very narrow bridges.

GERD surgery (fundoplication)
A surgical technique that strengthens the barrier to acid reflux when the lower esophageal sphincter does not work normally and there is gastro-esophageal reflux.

Geriatric medicine
The branch of medicine concerned with the diagnosis, treatment and prevention of disease in older people and the problems specific to aging. Also called geriatrics.

Germ cell tumor

German measles immunization
The standard MMR vaccine is given to prevent measles, mumps and rubella (German measles). The MMR vaccine is now given in two dosages. The first should be given at 12-15 months of age. The second vaccination should be given at 4-6 years. Most children should receive MMR vaccinations. Exceptions may include children born with an inability to fight off infection, some children with cancer, on treatment with radiation or drugs for cancer, on long term steroids (cortisone). People with severe allergic reactions to eggs or the drug neomycin should probably avoid the MMR vaccine. Pregnant women should wait until after delivery before being immunized with MMR. People with HIV or AIDS should normally receive MMR vaccine. Measles, mumps, and rubella vaccines may be administered as individual shots, if necessary, or as a measles- rubella combination.

German measles vaccine
A vaccine designed to prevent rubella, or German measles. The rubella vaccine has since been refined into the vaccine now known as MMR for mumps, measles and rubella. The congenital rubella syndrome is now largely a chapter in the history of medicine, thanks to the rubella vaccine.

Germanium
A nonessential trace element that has caused nephrotoxicity (kidney injury) and death when used chronically by humans, even at recommended levels of use.

Germinoma
A type of germ cell tumor.

Germline mutation
A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single-cell stage. When transmitted to a child, a germline mutation is incorporated in every cell of their body. Germline mutations play a key role in genetic diseases. They play a role, too, in certain types of cancer as, for example, the eye tumor retinoblastoma and Wilms tumor, a childhood malignancy of the kidney. A germline mutation is in contrast to a somatic mutation which is acquired in a single body cell.

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