Fluorescent antibody
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  Fluorescent antibody



Fluorescent antibody

    An antibody coupled with a fluorescent dye, used with a fluorescence microscope to detect antigen on cells, tissues, or microorganisms.

RELATED TERMS
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Antibody
An infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms (eg, bacteria, viruses) or toxins. Antibodies, known generally as immunoglobulins, are made and secreted by B-lymphocytes in response to stimulation by antigens. Each specific antibody binds only to the specific antigen that stimulated its production.

Microscope
A microscope (Greek: micron = small and scopos = aim) is an instrument for viewing objects that are too small to be seen by the naked or unaided eye. The science of investigating small objects using such an instrument is called microscopy, and the term microscopic means minute or very small, not easily visible with the unaided eye. In other words, requiring a microscope to examine.

Antigen
A substance which, when present in animal tissue, stimulates the production of antibodies



SIMILAR TERMS
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Fluocet
Fluocet is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.

Fluocinolone acetonide
Fluocinolone acetonide is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.

Fluocinonide
Fluocinonide is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinonide.

Fluocinonide emulsified base
Fluocinonide emulsified base is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinonide.

Fluonid
Fluonid is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.

Fluor-op
Fluor-op is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluorometholone.

Fluorescein
A compound used as a diagnostic aid to show injuries of the cornea or retina of the eye.

Fluorescein angiograms
Photographs of the back of the eye, taken after a fluorescent dye is placed in the blood stream.ÿ This is used to test the circulation in the retina of the eye.

Fluorescein angiography
Fluorescein Angiography is a diagnostic test used to assess pathology that affects the retina, choroid and/or iris of the eye. Fluorescein angiography is used to assess the blood flow of the eye and abnormal states are referred to as either hyperfluorescence or hypofluorescence relative to the normal amount of fluorescence. Fluorescein angiography involves an intravenous injection of sodium Fluorescein ( a dye) into the antecubical vein ( a vein in the arm) and then photographs are taken of the eye as the dye enters and leaves the blood system of the eye. The doctor will evaluate prefilling ( i.e., what the retina and choroid look like before the dye enters the eye), transit ( i.e., first passage of dye through the retina and choroid), recirculation (i.e., fluoroscien has become equally distributed throughout the eye and then starts to circulate through again) and later phase ( i.e., as the fluoroscien is eliminated from the body by the kidneys). The test lasts about 30 minutes. Nausea and vomiting are the most common side effects, occurring in about 5% or less of patients. Severe side effects ( e.g., anaphylaxis, death) have been reported but are very rare.

Fluorescein Angiography
A method of taking a picture of the flow of blood in the vessels of the eye by tracing the progress of an injected dye.

Fluorescence in situ hybridization (FISH)
A technique that can be used for prenatal diagnosis, in which specifically designed fluorescent molecules are used to "light up" particular genes or sections of chromosomes to make them visible under a microscope. The fluorescence makes even small abnormalities in the chromosomes visible.

Fluorescent in situ hybridization
An important molecular cytogenetic method for identifying chromosomes and parts of chromosomes, deciphering chromosome rearrangements, and locating genes on chromosomes.

Fluorescent microscope
A microscope equipped to examine material that fluoresces under ultraviolet light. Fluorescence microscopy is based on the principle that fluorescent materials emit visible light when they are irradiated with ultraviolet rays or with violet-blue visible rays.

Fluorescent treponemal antibody absorbed test
A blood serum screening test for syphilis designed to demonstrate the presence or absence of specific antibodies directed against the organism (Treponema pallidum) responsible for syphilis.

Fluoridation
1. In general, treatment with fluoride. 2. Specifically, the addition of fluoride to a water supply to help prevent dental caries.

Fluoride
A compound of fluorine with another element or radical. Fluoride compounds are present in drinking water and some foods. Fluoride ions replace hydroxyl ions in hydroxyapatite in teeth, forming fluorapatite, which leads to fewer cavities. Fluoride compounds are therefore added to some toothpastes and dentists may also give a yearly fluoride treatment. It is generally recommended that fluorides be added to water supplies in which the natural level is less than 0.7 ppm in water to increase the concentration to 0.7-1.2 ppm. The addition of fluoride to water systems is one of the major achievements in public health in the 20th century. Fluoride, in combination with calcium and vitamin D, also increases bone mass and lowers the risk of backbone fractures associated with osteoporosis. The only accepted adverse effect of fluoridation is dental fluorosis.

Fluorine f-18
Fluorine f-18 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): sodium fluoride, f-18.

Fluorobody
A hybrid molecule that combines the affinity and specificity of an antibody with the visibility of a green fluorescent protein (GFP). The GSP provides the antibody with a built-in detection system.

Fluoroplex
Fluoroplex is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluorouracil.

Fluoroscopy
An x-ray procedure that makes it possible to see internal organs in motion. Fluoroscopy uses x-ray to produce real-time video images. After the x-rays pass through the patient, instead of using film, they are captured by a device called an image intensifier and converted into light. The light is then captured by a TV camera and displayed on a video monitor.

Fluorosis
An abnormal condition caused by excessive intake of fluorine, characterized chiefly by mottling of the teeth.

Fluorouracil
A much-used anticancer drug that belongs to the family of drugs called antimetabolites. Full name: 5-fluorouracil. Abbreviation: 5-FU. 5-FU is a pyrimidine antagonist. 5-FU is similar in structure to the pyrimidine base thymine and functions to inhibit DNA synthesis both by blocking the formation of normal pyrimidine nucleotides via both enzyme inhibition and by interfering with DNA synthesis after incorporation into a growing DNA molecule. 5-FU is also able to block the production of RNA and thereby induce cell death. 5-FU affects the processing of messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), and small nuclear RNA (snRNA). 5-FU may also inhibit cell growth is through its ability to prevent the synthesis of thymine nucleotides from uracil nucleotides.

Fluothane
Fluothane is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): halothane.

Fluotrex
Fluotrex is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.

Fluoxetine
A drug used to treat depression. It belongs to the family of drugs called antidepressants.

Fluoxetine hcl
Fluoxetine hcl is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluoxetine hydrochloride.

Fluoxymesterone
Fluoxymesterone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluoxymesterone.



PREVIOUS AND NEXT TERMS
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Fertility clinic
A clinic or hospital specialized in fertility treatment.

Fab
Fragment of antibody containing the antigen-binding site, generated by cleavage of the antibody with the enzyme papain, which cuts at the hinge region N-terminally to the inter-H-chain disulphide bond and generates two Fab fragments from one antibody molecule.

Fab 2
A fragment of an antibody containing two antigen-binding sites generated by cleavage of the antibody molecule with the enzyme pepsin which cuts at the hinge region C-terminally to the inter-H-chain disulphide bond.

Fc
Fragment of antibody without antigen-binding sites, generated by cleavage with papain; the Fc fragment contains the C-terminal domains of the heavy immunoglobulin chains.

Fc receptor (FcR)
A receptor on a cell surface with specific binding affinity for the Fc portion of an antibody molecule. Fc receptors are found on many types of cells.

Fluorescent antibody

Freund's complete adjuvant
A water-in-oil emulsion that contains an immunogen, an emulsifying agent, and killed mycobacteria which enhance the immune response to the immunogen; termed "incomplete" Freund's adjuvant if mycobacteria are not included.

Faggie
Slang term, diminutive of fag or faggot, for a male who participates in sexual activity with another male and whose sexuoerotic status is homosexual.

Falling in love
The personal experience and manifest expression of becoming intensely, and possibly suddenly, attached or bonded to another person. It may be reciprocal and a source of great ecstasy, or one-sided and a source of great agony. Usually it is erotosexual.

Fantasy
In imagination, a series of mental representations connected by a story line or dramatic plot that may possibly be translated into actuality. Imagery in the mind that is fictive rather than perceptual, and that tells a story in either pictures or words. A fantasy, like a dream, may be a program of expectations for the future, or a replay of past happenings, or a combination of both.

Fantasize
Colloquial modification of the verb, to fantasy.

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