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Fluorescein angiography
Fluorescein angiography Fluorescein Angiography is a diagnostic test used to assess pathology that affects the retina, choroid and/or iris of the eye. Fluorescein angiography is used to assess the blood flow of the eye and abnormal states are referred to as either hyperfluorescence or hypofluorescence relative to the normal amount of fluorescence. Fluorescein angiography involves an intravenous injection of sodium Fluorescein ( a dye) into the antecubical vein ( a vein in the arm) and then photographs are taken of the eye as the dye enters and leaves the blood system of the eye. The doctor will evaluate prefilling ( i.e., what the retina and choroid look like before the dye enters the eye), transit ( i.e., first passage of dye through the retina and choroid), recirculation (i.e., fluoroscien has become equally distributed throughout the eye and then starts to circulate through again) and later phase ( i.e., as the fluoroscien is eliminated from the body by the kidneys). The test lasts about 30 minutes. Nausea and vomiting are the most common side effects, occurring in about 5% or less of patients. Severe side effects ( e.g., anaphylaxis, death) have been reported but are very rare.
RELATED TERMS--------------------------------------
Fluorescein A compound used as a diagnostic aid to show injuries of the cornea or retina of the eye.
Angiography An x-ray that uses dye to detect bleeding in the gastrointestinal tract.
Diagnostic Pertaining to a diagnosis; usually refers to a characteristic or criteria which is critical for a specific diagnosis.
Pathology Study of disease.
Retina A membrane lining the inside of the back of the eye that contains light-sensitive nerve cells that convert focused light into nerve impulses, making vision possible.
Choroid This is the vascular coat between the sclera and the retina, which furnishes blood and nutrition to the outer layer of the retina.
Iris The colored part of the eye with a hole (pupil) in the center. It regulates the amount of light entering the eye – the dimmer the lighting the more light the iris lets into the eye by widening the pupil.
Eye The organ of sight. The eye has a number of components. These components include but are not limited to the cornea, iris, pupil, lens, retina, macula, optic nerve, choroid and vitreous.
Blood The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.
Abnormal Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).
Intravenous Introducing a fluid into the bloodstream through a vein (usually in the patient's forearm).
Injection Medication which is put into the body via a syringe and a needle.
Sodium A mineral found in most of the foods we eat. The largest source of dietary sodium comes from sodium chloride or table salt. Intake of sodium tends to increase the retention of water.
Vein A blood vessel that carries blood from the body back into the heart.
Doctor 1. One whose occupation is to treat diseases, particularly a physician, dentist, or veterinarian with an appropriate license. 2. A teacher (particularly at a college or university), a scholar, or one who holds a postgraduate degree (especially a Ph.D. degree). 3. A shaman.
Nausea The feeling of wanting to throw up (vomit).
Vomiting The release of stomach contents through the mouth.
Anaphylaxis Immediate hypersensitivity response to antigenic challenge, mediated by IgE and mast cells. It is a life-threatening allergic reaction, caused by the release of pharmacologically active agents.
SIMILAR TERMS--------------------------------------
Fluocet Fluocet is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluocinolone acetonide Fluocinolone acetonide is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluocinonide Fluocinonide is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinonide.
Fluocinonide emulsified base Fluocinonide emulsified base is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinonide.
Fluonid Fluonid is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluor-op Fluor-op is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluorometholone.
Fluorescein A compound used as a diagnostic aid to show injuries of the cornea or retina of the eye.
Fluorescein angiograms Photographs of the back of the eye, taken after a fluorescent dye is placed in the blood stream.˙ This is used to test the circulation in the retina of the eye.
Fluorescence in situ hybridization (FISH) A technique that can be used for prenatal diagnosis, in which specifically designed fluorescent molecules are used to "light up" particular genes or sections of chromosomes to make them visible under a microscope. The fluorescence makes even small abnormalities in the chromosomes visible.
Fluorescent antibody An antibody coupled with a fluorescent dye, used with a fluorescence microscope to detect antigen on cells, tissues, or microorganisms.
Fluorescent in situ hybridization An important molecular cytogenetic method for identifying chromosomes and parts of chromosomes, deciphering chromosome rearrangements, and locating genes on chromosomes.
Fluorescent microscope A microscope equipped to examine material that fluoresces under ultraviolet light. Fluorescence microscopy is based on the principle that fluorescent materials emit visible light when they are irradiated with ultraviolet rays or with violet-blue visible rays.
Fluorescent treponemal antibody absorbed test A blood serum screening test for syphilis designed to demonstrate the presence or absence of specific antibodies directed against the organism (Treponema pallidum) responsible for syphilis.
Fluoridation 1. In general, treatment with fluoride. 2. Specifically, the addition of fluoride to a water supply to help prevent dental caries.
Fluoride A compound of fluorine with another element or radical. Fluoride compounds are present in drinking water and some foods. Fluoride ions replace hydroxyl ions in hydroxyapatite in teeth, forming fluorapatite, which leads to fewer cavities. Fluoride compounds are therefore added to some toothpastes and dentists may also give a yearly fluoride treatment. It is generally recommended that fluorides be added to water supplies in which the natural level is less than 0.7 ppm in water to increase the concentration to 0.7-1.2 ppm. The addition of fluoride to water systems is one of the major achievements in public health in the 20th century. Fluoride, in combination with calcium and vitamin D, also increases bone mass and lowers the risk of backbone fractures associated with osteoporosis. The only accepted adverse effect of fluoridation is dental fluorosis.
Fluorine f-18 Fluorine f-18 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): sodium fluoride, f-18.
Fluorobody A hybrid molecule that combines the affinity and specificity of an antibody with the visibility of a green fluorescent protein (GFP). The GSP provides the antibody with a built-in detection system.
Fluoroplex Fluoroplex is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluorouracil.
Fluoroscopy An x-ray procedure that makes it possible to see internal organs in motion. Fluoroscopy uses x-ray to produce real-time video images. After the x-rays pass through the patient, instead of using film, they are captured by a device called an image intensifier and converted into light. The light is then captured by a TV camera and displayed on a video monitor.
Fluorosis An abnormal condition caused by excessive intake of fluorine, characterized chiefly by mottling of the teeth.
Fluorouracil A much-used anticancer drug that belongs to the family of drugs called antimetabolites. Full name: 5-fluorouracil. Abbreviation: 5-FU. 5-FU is a pyrimidine antagonist. 5-FU is similar in structure to the pyrimidine base thymine and functions to inhibit DNA synthesis both by blocking the formation of normal pyrimidine nucleotides via both enzyme inhibition and by interfering with DNA synthesis after incorporation into a growing DNA molecule. 5-FU is also able to block the production of RNA and thereby induce cell death. 5-FU affects the processing of messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), and small nuclear RNA (snRNA). 5-FU may also inhibit cell growth is through its ability to prevent the synthesis of thymine nucleotides from uracil nucleotides.
Fluothane Fluothane is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): halothane.
Fluotrex Fluotrex is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluoxetine A drug used to treat depression. It belongs to the family of drugs called antidepressants.
Fluoxetine hcl Fluoxetine hcl is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluoxetine hydrochloride.
Fluoxymesterone Fluoxymesterone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluoxymesterone.
PREVIOUS AND NEXT TERMS--------------------------------------
Fioricet Medication used in the treatment of tension headaches.
Fiorinal Medication used in the treatment of tension headaches.
Focalin Integral part of total treatment program to stabilize ADHD/ADD.
Foradil Used in the treatment of asthma and in the prevention of bronchospasm.
Floaters Small condensations of cells in the vitreous body, the fluid in the eye, which cast shadows on the back of the eye, known as the retina. This is normally associated with aging. Floaters may indicate a more serious problem such as a retinal detachment. If you suddenly see a lot of floaters, please see your eye doctor.
Fluorescein angiography
Fovea A central portion of the retina and macula that contains only cones. The fovea is the only part of the eye that is capable of 20/20 or better vision.
Fundus The back part of the eye that can be seen with an instrument called an ophthalmoscope. Visible features include the retina with its blood vessels, the optic nerve and choroid. The fundus surrounds the fovea, that part of the eye used for reading.
Fundus flavimaculatus See Stargardt’s disease.
flurazepam A hypnotic substance.
Fludiazepam A tranquilizer.
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