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Fluorescein
Fluorescein A compound used as a diagnostic aid to show injuries of the cornea or retina of the eye.
RELATED TERMS--------------------------------------
Diagnostic Pertaining to a diagnosis; usually refers to a characteristic or criteria which is critical for a specific diagnosis.
Cornea The front part of the eye that acts as a window for the entrance of light rays. It is attached to the other outer coat of the eye, the sclera; the white part of the eye. The cornea provides a significant amount of focusing power for the eye (the rest is provided by the lens). Because it has many nerve fibers, an injury or foreign body causes significant pain and discomfort.
Retina A membrane lining the inside of the back of the eye that contains light-sensitive nerve cells that convert focused light into nerve impulses, making vision possible.
Eye The organ of sight. The eye has a number of components. These components include but are not limited to the cornea, iris, pupil, lens, retina, macula, optic nerve, choroid and vitreous.
SIMILAR TERMS--------------------------------------
Fluocet Fluocet is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluocinolone acetonide Fluocinolone acetonide is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluocinonide Fluocinonide is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinonide.
Fluocinonide emulsified base Fluocinonide emulsified base is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinonide.
Fluonid Fluonid is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluor-op Fluor-op is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluorometholone.
Fluorescein angiograms Photographs of the back of the eye, taken after a fluorescent dye is placed in the blood stream.ÿ This is used to test the circulation in the retina of the eye.
Fluorescein angiography Fluorescein Angiography is a diagnostic test used to assess pathology that affects the retina, choroid and/or iris of the eye. Fluorescein angiography is used to assess the blood flow of the eye and abnormal states are referred to as either hyperfluorescence or hypofluorescence relative to the normal amount of fluorescence. Fluorescein angiography involves an intravenous injection of sodium Fluorescein ( a dye) into the antecubical vein ( a vein in the arm) and then photographs are taken of the eye as the dye enters and leaves the blood system of the eye. The doctor will evaluate prefilling ( i.e., what the retina and choroid look like before the dye enters the eye), transit ( i.e., first passage of dye through the retina and choroid), recirculation (i.e., fluoroscien has become equally distributed throughout the eye and then starts to circulate through again) and later phase ( i.e., as the fluoroscien is eliminated from the body by the kidneys). The test lasts about 30 minutes. Nausea and vomiting are the most common side effects, occurring in about 5% or less of patients. Severe side effects ( e.g., anaphylaxis, death) have been reported but are very rare.
Fluorescein Angiography A method of taking a picture of the flow of blood in the vessels of the eye by tracing the progress of an injected dye.
Fluorescence in situ hybridization (FISH) A technique that can be used for prenatal diagnosis, in which specifically designed fluorescent molecules are used to "light up" particular genes or sections of chromosomes to make them visible under a microscope. The fluorescence makes even small abnormalities in the chromosomes visible.
Fluorescent antibody An antibody coupled with a fluorescent dye, used with a fluorescence microscope to detect antigen on cells, tissues, or microorganisms.
Fluorescent in situ hybridization An important molecular cytogenetic method for identifying chromosomes and parts of chromosomes, deciphering chromosome rearrangements, and locating genes on chromosomes.
Fluorescent microscope A microscope equipped to examine material that fluoresces under ultraviolet light. Fluorescence microscopy is based on the principle that fluorescent materials emit visible light when they are irradiated with ultraviolet rays or with violet-blue visible rays.
Fluorescent treponemal antibody absorbed test A blood serum screening test for syphilis designed to demonstrate the presence or absence of specific antibodies directed against the organism (Treponema pallidum) responsible for syphilis.
Fluoridation 1. In general, treatment with fluoride. 2. Specifically, the addition of fluoride to a water supply to help prevent dental caries.
Fluoride A compound of fluorine with another element or radical. Fluoride compounds are present in drinking water and some foods. Fluoride ions replace hydroxyl ions in hydroxyapatite in teeth, forming fluorapatite, which leads to fewer cavities. Fluoride compounds are therefore added to some toothpastes and dentists may also give a yearly fluoride treatment. It is generally recommended that fluorides be added to water supplies in which the natural level is less than 0.7 ppm in water to increase the concentration to 0.7-1.2 ppm. The addition of fluoride to water systems is one of the major achievements in public health in the 20th century. Fluoride, in combination with calcium and vitamin D, also increases bone mass and lowers the risk of backbone fractures associated with osteoporosis. The only accepted adverse effect of fluoridation is dental fluorosis.
Fluorine f-18 Fluorine f-18 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): sodium fluoride, f-18.
Fluorobody A hybrid molecule that combines the affinity and specificity of an antibody with the visibility of a green fluorescent protein (GFP). The GSP provides the antibody with a built-in detection system.
Fluoroplex Fluoroplex is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluorouracil.
Fluoroscopy An x-ray procedure that makes it possible to see internal organs in motion. Fluoroscopy uses x-ray to produce real-time video images. After the x-rays pass through the patient, instead of using film, they are captured by a device called an image intensifier and converted into light. The light is then captured by a TV camera and displayed on a video monitor.
Fluorosis An abnormal condition caused by excessive intake of fluorine, characterized chiefly by mottling of the teeth.
Fluorouracil A much-used anticancer drug that belongs to the family of drugs called antimetabolites. Full name: 5-fluorouracil. Abbreviation: 5-FU. 5-FU is a pyrimidine antagonist. 5-FU is similar in structure to the pyrimidine base thymine and functions to inhibit DNA synthesis both by blocking the formation of normal pyrimidine nucleotides via both enzyme inhibition and by interfering with DNA synthesis after incorporation into a growing DNA molecule. 5-FU is also able to block the production of RNA and thereby induce cell death. 5-FU affects the processing of messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), and small nuclear RNA (snRNA). 5-FU may also inhibit cell growth is through its ability to prevent the synthesis of thymine nucleotides from uracil nucleotides.
Fluothane Fluothane is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): halothane.
Fluotrex Fluotrex is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluocinolone acetonide.
Fluoxetine A drug used to treat depression. It belongs to the family of drugs called antidepressants.
Fluoxetine hcl Fluoxetine hcl is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluoxetine hydrochloride.
Fluoxymesterone Fluoxymesterone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluoxymesterone.
PREVIOUS AND NEXT TERMS--------------------------------------
Fetal Having to do with the fetus.
Fibroid A noncancerous tumor of the uterus composed of muscle fibers. Also called uterine myoma.
Fissure A narrow slit.
Flaccid Soft and flabby. Often used to describe complete paralysis (loss of movement) without muscle spasm.
Flatfoot A condition in which the normal arch of the foot is absent.
Fluorescein
Folliculitis Inflammation of the hair follicles.
Fontanelle A soft spot in the skull of an infant formed by the normal separation between the bony plates of the skull.
Fracture Broken, especially a broken bone.
Frenulum A fold of skin or mucous membrane that limits the movement of a body part. For example, the frenulum linguae is the midline fold under the tongue that attaches it to the floor of the mouth.
Frostbite Damage to tissue as a result of exposure to freezing temperatures.
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