Five-day fever
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  Five-day fever



Five-day fever

   Also called trench fever, this is a disease borne by body lice that was first recognized in the trenches of World War I, when it is estimated to have affected more than a million people in Russia and on the fronts in Europe. Trench fever was again a major problem in the military in World War II and is seen endemically in Mexico, Africa, E. Europe, and elsewhere. The cause of trench fever is Bartonella quintana (also called Rochalimaea quintana), an unusual rickettsial organism that multiplies in the gut of the body louse. Transmission of the rickettsia to people can occur by rubbing infected louse feces into abraded (scuffed) skin or into the conjunctivae (whites of the eyes). The disease is classically a 5-day fever. The onset of symptoms is sudden with high fever, severe headache, back pain and leg pain and a fleeting rash. Recovery takes a month or more. Relapses are common.

RELATED TERMS
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Fever
When body temperature rises above its normal level - defined as 98.6 degrees F, though it varies by individual and time of day. A fever is the sign of an immune system at work and usually indicates an infection.

Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Lice
Tiny wingless insects that feed on human blood, most often on the scalp. Spread by skin-to-skin contact and by sharing clothes, combs, and bedding.

Organism
A living thing, such as an animal, a plant, a bacterium, or a fungus.

Feces
Stool.

Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).

Headache
Primary - includes tension (muscular contraction), vascular (migraine), and cluster headaches not caused by other underlying medical conditions. Secondary - includes headaches that result from other medical conditions. These may also be referred to as traction headaches or inflammatory headaches.

Pain
An unpleasant sensory or emotional experience primarily associated with tissue damage, or described in terms of tissue damage, or both.

Rash
A reddish spot or patch of irritated skin. Rashes can be caused byillnesses, allergies, and heat and are usually temporary.



SIMILAR TERMS
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Five Elements (Five Phases)
Earth, Metal, Water, Wood, and Fire as manifestations ("phases" or "transformations") of chi. The expression "five elements" derives from two Chinese words|wu ("five") and xing ("move" or "walk"). Its implicit meaning is "five processes." According to ancient Chinese cosmology, the Five Elements compose everything. In Chinese medicine, each of the Five Elements symbolizes a group of physiologic functions|"Earth" (soil) represents balance or neutrality; Metal (coal, fossils, and inorganic matter), decay; Water (moisture), a state of maximum rest leading to a change of functional direction; Wood (organic matter), a growth phase; and Fire (gases), maximum activity.

Five-lipoxygenase activating protein
A gene that helps make a leukotriene, a signal that activates the white blood cells involved in inflammation. FLAP stands for 5-lipoxygenase-activating protein. FLAP has been implicated in a number of inflammatory responses, including asthma, arthritis, psoriasis, heart attack and stroke. FLAP was the first gene discovered to be a major risk factor for the common form of heart attack and the second major genetic factor identified in the common form of stroke.



PREVIOUS AND NEXT TERMS
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Fish bowl granuloma
Localized nodular skin inflammation (small reddish raised areas of skin) caused by a bacterium called mycobacterium marinum. Fish bowl granuloma is typically acquired by occupational or recreational exposure to salt or fresh water, often resulting from minor trauma during caring for aquariums. The diagnosis is suggested by the history of exposure and confirmed by culturing tissue specimens which yield the microscopic organism, mycobacterium marinum. The infection can be treated with a variety of antibiotics, including doxycycline, minocycline, clarithromycin, rifampin, and trimethoprim-sulfamethoxazole. Also called "swimming pool granuloma."

Fish oil, omega-3
A class of fatty acids found in fish oils, especially from salmon and other cold-water fish, that acts to lower the levels of cholesterol and LDL (low-density lipoproteins) in the blood. (LDL cholesterol is the "bad" cholesterol.) Omega-3 fish oil is therefore thought to be a neutraceutical, a food that provides health benefits. Eating fish has been reported to protect against late age-related macular degeneration, a common eye disease. The maximum benefit appears to be from eating fish once a week.

Fish-odor syndrome
An inborn error of metabolism associated with an offensive body odor, the smell of rotting fish, due to the excessive excretion of trimethylaminuria (TMA) in urine, sweat, and breath. Persons with TMA may experience tachycardia (fast heart rate) and severe hypertension (high blood pressure) after eating cheese (which contains tyramine) and after using nasal sprays containing epinephrine. TMA is caused by a mutation (change) in the gene for an enzyme, flavin-containing monooxygenase-3 (FMO3) encoded by a gene on chromosome #1. The FMO3 enzyme metabolizes tyramine (which is in cheese). The syndrome is associated with various psychosocial reactions, including social isolation, clinical depression and attempted suicide.

Fissure, palpebral
The opening for the eye between the eyelids.

Fistula, anal
An opening in the skin near the anus that leads into a blind pouch or may connect through a tunnel with the rectal canal.

Five-day fever

Five-lipoxygenase activating protein
A gene that helps make a leukotriene, a signal that activates the white blood cells involved in inflammation. FLAP stands for 5-lipoxygenase-activating protein. FLAP has been implicated in a number of inflammatory responses, including asthma, arthritis, psoriasis, heart attack and stroke. FLAP was the first gene discovered to be a major risk factor for the common form of heart attack and the second major genetic factor identified in the common form of stroke.

Fixation, external
A procedure that stabilizes and joins the ends of fractured (broken) bones by a splint or cast. External fixation is as opposed to internal fixation in which the ends of the fractured bone are joined by mechanical devices such as metal plates, pins, rods, wires or screws.

Fixation, internal
A surgical procedure that stabilizes and joins the ends of fractured (broken) bones by mechanical devices such as metal plates, pins, rods, wires or screws. Internal fixation is as opposed to external fixation of a fracture by a splint or cast.

Fixative
A medium such as a solution or spray that preserves specimens of tissues or cells. Most biopsies and specimens removed at surgery are fixed in a solution such as formalin (dilute formaldehyde) before further processing takes place. Other common ingredients used in fixatives are alcohol, mercuric chloride, potassium dichromate and sodium sulfate.

Flail chest
When enough ribs are broken (usually from a crush injury) to compromise the rigidity of the chest wall. On inspiration, the chest wall moves inward instead of outward and the opposite on expiration.

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