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Fibrositis
Fibrositis Inflammation of fibrous connective tissues in muscles. It often affects the muscles of the trunk and back. It may be a symptom of another disease, such as Sciatica, but in most cases the cause is unknown. Pain and stiffness.
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Inflammation A reaction to an injury to the body - by infection, chemicals or physical agents. The symptoms can be - depending on the location of the injury- redness, swelling, heat and pain. The purpose of the inflammation is to dilute and destroy the agent causing the inflammation. To do this, the immune system starts a cascade of actions that causes active cells to gather at the affected location. It is these cells and fluids that cause the redness, swelling, heat and pain.
Symptom A subjective manifestation of a pathological condition. Symptoms are reported by the affected individual rather than observed by the examiner.
Disease Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Sciatica A common pregnancy-related condition, caused by pressure on the sciatic nerve, which passes through the pelvis. Symptoms, which include pain, tingling, or numbness in the lower back and down the legs, often last only a few hours but can, in severe cases, linger throughout pregnancy.
Pain An unpleasant sensory or emotional experience primarily associated with tissue damage, or described in terms of tissue damage, or both.
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Fibrates for lowering cholesterol Fibrates are cholesterol-lowering drugs that are primarily effective in lowering triglycerides and, to a lesser extent, in increasing HDL-cholesterol levels.
Fibril The diminutive of fiber. A small fiber, a fine thread.
Fibrillation Rapid contractions of the heart muscles.
Fibrillation, atrial An abnormal irregular heart rhythm whereby electrical signals are generated chaotically throughout the upper chambers (atria) of the heart. Although many persons with atrial fibrillation have no symptoms, the most common symptom is palpitations, an uncomfortable awareness of the rapid and irregular heartbeat. Atrial fibrillation can cause blood clots that travel from the heart to the brain, causing stroke. Treatment of atrial fibrillation involves controlling the risk factors, medications to slow the heart rate and/or convert the heart to normal rhythm, and preventing complications of blood clotting.
Fibrillation, auricular Essentially the same as atrial fibrillation.
Fibrillation, ventricular An abnormal irregular heart rhythm whereby there are very rapid uncoordinated fluttering contractions of the lower chambers (ventricles) of the heart. Ventricular fibrillation disrupts the synchrony between the heartbeat and the pulse beat. Ventricular fibrillation is commonly associated with heart attacks or scarring of the heart muscle from previous heart attack. Ventricular fibrillation is life threatening.
Fibrin A filamentous protein formed from the precursor fibrinogen by the enzyme thrombin.
Fibrinogen The protein from which is generated fibrin, the essence of a normal blood clot.
Fibroadenoma Noncancerous, firm, rubbery lump in the breast that is painless and moves around easily when touched.
Fibroblast A connective tissue cell.
Fibroblast growth factor receptor 2 A mutation (change) in the fibroblast growth factor receptor 2 (FGFR2) gene on chromosome 10 causes the best-known type of acrocephalosyndactyly, namely Apert syndrome which is characterized by abnormalities of the skull and face and the hands and feet. There is premature closure of some of the sutures of the skull (craniosynostosis) resulting in an abnormally shaped head (which is unusually tall but short from front-to-back) and an abnormally shaped face with shallow eye sockets and underdevelopment of the midface. There is fusion of fingers and toes (syndactyly) and broad ends of the thumbs and big toes. Surgery is often useful with the skull, face, hands and feet. Different mutations in FGFR2 are responsible for two other genetic diseases, namely, Pfeiffer syndrome (another type of acrocephalosyndactyly) and Crouzon syndrome (purely a craniofacial disorder with no hand or foot problems). All are inherited as dominant traits.
Fibrocystic breasts Noncancerous condition in which small lumps and cysts develop in the breasts.
Fibrodysplasia ossificans progressiva (FOP) A rare but dramatic genetic disorder that turns muscles, tendons and ligaments into bone, threatening to transform the victim into "a statue of stone." FOP is characterized by physical handicap due to bone forming in the wrong places and malformed big toes which often contain only one bone. Other features of FOP can include short thumbs, fifth finger clinodactyly (pinkie curved toward the thumb), malformed cervical (neck) vertebrae, short broad neck of the femur (thighbone), deafness, scalp baldness, and mild mental retardation.
Fibroid A noncancerous tumor of the uterus composed of muscle fibers. Also called uterine myoma.
Fibroids Noncancerous growths in, on, or within the walls of the uterus that develop from muscle cells in the wall of the uterus.
Fibroma A mass composed of fibrous tissue or connective tissue. Also called a fibroid tumor or fibroid.
Fibroma, cemento-ossifying A hard fibrous lesion that continues to grow, sometimes to very large size, unless treated, most frequently seen in the jaw or mouth, sometimes in connection with a fracture or another type of injury. Treatment is by surgery. Abbreviated COF.
Fibroma, desmoplastic A rare type of primary bone tumor characteristically composed of well-differentiated cells that produce collagen. Desmoplastic fibromas are discovered most often in the first three decades of life, in the mandible (the femur and pelvis are also favored sites). Although benign, these tumors are locally infiltrative and may cause pain and swelling or an effusion (if near a joint). Treatment is surgical removal but the tumor may recur.
Fibroma, nonossifying A growing lesion with a fibroma structure. Treatment is by surgery.
Fibromyalgia Fibromyalgia is a debilitating chronic syndrome (constellation of signs and symptoms) characterized by diffuse pain, fatigue, and a wide range of other symptoms. It is not contagious, and recent studies suggest that people with fibromyalgia may be genetically predispose. It affects more women than men, with a ratio globally of 3-5:1. Fibromyalgia is seen in 3-10% of the general population, and is mostly found between the ages 20 and 50.
Fibrosarcoma A malignant tumor that begins in fibrous connective tissue at the ends of the arm or leg bones and may spread to surrounding soft tissue. Fibrosarcoma is the most common soft tissue sarcoma found in children under one year of age. It presents as a rapidly growing mass at birth or early infancy. Fibrosarcoma can also occur in older children and adults. The symptoms may include a lump, soreness, pain, or a limp (if the tumor is in the leg).
Fibrosis The presence of scar tissue or collagen fibers in any tissue. In the liver, fibrosis or scarring of the liver damages the architecture and thus the functionality of the organ. Fibrosis, combined with the liver’s ability to regenerate, causes cirrhosis (regeneration within the scar tissue).
Fibrosis, cystic One of the most common grave genetic (inherited) diseases, CF affects the exocrine glands and is characterized by the production of abnormal secretions, leading to mucous build-up.
Fibrosis, radiation Scarring of the lungs from radiation. Radiation fibrosis is a sequel of radiation pneumonitis (inflammation of the lungs due to radiation), as from radiation therapy. Radiation pneumonitis typically occurs after radiation treatments for cancer within the chest or breast and usually manifests itself 2 weeks to 6 months after completion of radiation therapy. Symptoms include shortness of breath upon activity, cough and fever. Radiation pneumonitis frequently is discovered as an incidental finding on chest x-ray in patients who have no symptoms.
Fibrous dysplasia, monostotic Excessive growth of hard fibrous tissue that replaces normal bone tissue in a single bone. Symptoms may include pain and fracture of the bone. Most cases are diagnosed in adolescence and young adulthood and remain unchanged throughout life. The prognosis (outlook) is usually very good.
Fibrous dysplasia, polyostotic A genetic disorder of bones, skin pigmentation and hormonal problems with premature sexual development. Also called McCune-Albright syndrome or the Albright syndrome. In the syndrome, there is bone disease with fractures and deformity of the legs, arms and skull; pigment patches of the skin; and endocrine (hormonal) disease with early puberty (early menstrual bleeding, development of breasts and pubic hair) and an increased rate of growth. Polyostotic fibrous dysplasia is usually caused by mosaicism for a mutation in a gene called GNAS1 (Guanine Nucleotide binding protein, Alpha Stimulating activity polypeptide 1).
Fibrous tissue Tissue consisting of or containing fibers.
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Farsightedness Hyperopia occurs when the eyeball is too short from front to back, or the eye's focusing mechanism is too weak, causing light rays to be focused behind, rather than on the retina. People with hyperopia have difficulty seeing objects close up.
Fanconi anemia A rare inherited type of aplastic anemia that is often but not always associated with skeletal abnormalities. Fanconi anemia carries an increased risk to the patient of developing acute myelogenous leukemia. The disorder may be treated by stem cell transplantation.
Forensics Forensics or forensic science is the application of science to questions which are of interest to the legal system. For example, forensic pathology is the study of the human body to determine cause and manner of death. Criminalistics is the application of various sciences to answer questions relating to examination and comparison of biological evidence, trace evidence, impression evidence, drugs and firearms. Forensic odontology is the study of the uniqueness of dentition. Etcetera.
Fibula Smaller of the two bones in the lower leg; runs from the knee to the ankle along the outside of the lower leg.
Foot The distal portion of the leg, upon which an individual stands and walks. It consists, in man, of the tarsus, metatarsus, and phalanges and the tissues encompassing them.
Fibrositis
Fifth disease Slapped cheek disease (erythema infectiosum) is also known as fifth disease because it was the last of five "red rash" childhood diseases to be defined after scarlet fever, measles, rubella, and roseola. It is characterised by fever and red cheeks.
Foot and Mouth disease Foot-and-mouth disease is a severe, highly communicable viral disease of cattle and swine. It also affects sheep, goats, deer and other cloven-hooved ruminants. The disease is characterized by fever and blister-like lesions followed by erosions on the tongue and lips, in the mouth, on the teats and between the hooves. Many affected animals recover, but the disease leaves them debilitated. It causes severe losses in the production of meat and milk. The disease is caused by a virus. There are at least seven separate types and many subtypes of the FMD virus.
Fetal Alcohol Syndrome (FAS) A pattern of retarded growth and development, both mental and physical, with cranial, facial, 1imb, and cardiovascular defects, found in some children of mothers whose alcohol consumption during pregnancy can be classed as hazardous. The commonest abnormalities are: prenatal and postnatal growth deficiency, microcephaly, developmental delay or mental retardation, short palpebral fissures, a short upturned nose with sunken nasal bridge and a thin upper lip, abnormal palmar creases, and cardiac (especially septal) defects. Many other more subtle abnormalities have also been attributed to the effects of alcohol on the fetus.
Fragile X Syndrome Fragile X Syndrome is the most common inherited cause of mental impairment, and the most common known cause of autism. Fragile X syndrome is a genetic disorder caused by a mutation of the FMR1 gene on the X chromosome, a mutation found in 1 out of every 2000 males and 1 out of every 4000 females. Typically the FMR1 gene contains between 6 and 53 repeats of the CGG codon. In people with the disorder, the FMR1 allele has over 230 repeats.
Follicle The tiny shaft in the skin through which a hair grows, and sebum is excreted from sebaceous glands to the surface of the skin.
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