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Fiber FISH
Fiber FISH A cytogenetic (chromosome) laboratory technique in which FISH (fluorescence in situ hybridization) is done on chromosomes that have been mechanically stretched. Fiber FISH provides a higher resolution of analysis than conventional FISH and yields more precise information as to the localization of a specific DNA probe on the chromosome.
RELATED TERMS--------------------------------------
FISH
Abbreviation for fluorescence in situ hybridization, a molecular technique used in chromosome studies. FISH employs fluorescent (fluorescein tags) that glow under ultraviolet light to detect the hybridization (the combination) of molecular probes with specific chromosomes and specific chromosome regions. In FISH, the process vividly paints chromosomes or portions of chromosomes with fluorescent molecules.
Chromosomes
Filaments of genetic material in every cell nucleus that are made up of genes and that transmit genetic information from one generation of cells to the next.
Fiber
A substance in foods that comes from plants. Fiber helps with digestion by keeping stool soft so that it moves smoothly through the colon. Soluble fiber dissolves in water. Soluble fiber is found in beans, fruit, and oat products. Insoluble fiber does not dissolve in water. Insoluble fiber is found in whole-grain products and vegetables.
Analysis
A psychology term for processes used to gain understanding of complex emotional or behavioral issues.
Chromosome
A structural unit within a eukaryotic nucleus that carries genes. A chromosome consists of a long, continuous strand of DNA and associated proteins.
SIMILAR TERMS--------------------------------------
Fiber
A substance in foods that comes from plants. Fiber helps with digestion by keeping stool soft so that it moves smoothly through the colon. Soluble fiber dissolves in water. Soluble fiber is found in beans, fruit, and oat products. Insoluble fiber does not dissolve in water. Insoluble fiber is found in whole-grain products and vegetables.
Fiber and bowel disorders
High fiber diets help delay the progression of diverticulosis and, at least, reduce the bouts of diverticulitis. In many cases, it helps reduce the symptoms of the Irritable Bowel Syndrome (IBS) (also called spastic colitis, mucus colitis, and nervous colon syndrome.) It is generally accepted that a diet high in fiber is protective, or at least reduces the incidence, of colon polyps and colon cancer.
Fiber and constipation
Insoluble fiber retains water in the colon, resulting in a softer and larger stool. It is used effectively in treating constipation resulting from poor dietary habits. Bran is particularly rich in insoluble fiber.
Fiber and diabetes
Soluble fibers (oat bran, apples, citrus, pears, peas/beans, psyllium, etc.) slow down the digestion of carbohydrates (sugars), which results in better glucose metabolism. Some patients with the adult-onset diabetes may actually be successfully treated with a high-fiber diet alone, and those on insulin, can often reduce their insulin requirements by adhering to a high-fiber diet.
Fiber, elastic
A slender fiber in connective tissue that is rich in the protein elastin and has an elastic quality.
Fiber, soluble and insoluble
Fiber (the portion of plants that cannot be digested by the human digestive tract) is classified as soluble and insoluble. Oats, beans, dried peas, and legumes are major sources of soluble fiber whereas wheat bran, whole grain products, and vegetables are major sources of insoluble fiber. Fruits, vegetables, and barley are sources of both insoluble and soluble fiber. Soluble fiber and insoluble fiber differ in function. For example, soluble fiber delays the time of transit through the intestine whereas insoluble fiber speeds up intestinal transit. For another example, soluble fiber and decreases the level of cholesterol in the blood whereas insoluble fiber has no effect on serum cholesterol.
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FGFR2
A mutation (change) in the fibroblast growth factor receptor 2 (FGFR2) gene on chromosome 10 causes the best-known type of acrocephalosyndactyly, namely Apert syndrome which is characterized by abnormalities of the skull and face and the hands and feet. There is premature closure of some of the sutures of the skull (craniosynostosis) resulting in an abnormally shaped head (which is unusually tall but short from front-to-back) and an abnormally shaped face with shallow eye sockets and underdevelopment of the midface. There is fusion of fingers and toes (syndactyly) and broad ends of the thumbs and big toes. Surgery is often useful with the skull, face, hands and feet. Different mutations in FGFR2 are responsible for two other genetic diseases, namely, Pfeiffer syndrome (another type of acrocephalosyndactyly) and Crouzon syndrome (purely a craniofacial disorder with no hand or foot problems).
FGFR3
Abbreviation for fibroblast growth factor receptor 3. Mutations in the FGFR3 gene are known to cause three different syndromes -- hypochondroplasia, achondroplasia, and thanatophoric dysplasia. These syndromes represent variations in severity. Hypochondroplasia is the mildest and thanatophoric dysplasia (also called thanatophoric dwarfism) is the most severe. In fact, thanatophoric dysplasia is a type of dwarfism in which death usually occurs in the first hours of life. FGF3 is an example of how different syndromes can result from mutations in a single gene.
Fiber and bowel disorders
High fiber diets help delay the progression of diverticulosis and, at least, reduce the bouts of diverticulitis. In many cases, it helps reduce the symptoms of the Irritable Bowel Syndrome (IBS) (also called spastic colitis, mucus colitis, and nervous colon syndrome.) It is generally accepted that a diet high in fiber is protective, or at least reduces the incidence, of colon polyps and colon cancer.
Fiber and constipation
Insoluble fiber retains water in the colon, resulting in a softer and larger stool. It is used effectively in treating constipation resulting from poor dietary habits. Bran is particularly rich in insoluble fiber.
Fiber and diabetes
Soluble fibers (oat bran, apples, citrus, pears, peas/beans, psyllium, etc.) slow down the digestion of carbohydrates (sugars), which results in better glucose metabolism. Some patients with the adult-onset diabetes may actually be successfully treated with a high-fiber diet alone, and those on insulin, can often reduce their insulin requirements by adhering to a high-fiber diet.
Fiber FISH
Fiber, elastic
A slender fiber in connective tissue that is rich in the protein elastin and has an elastic quality.
Fiber, soluble and insoluble
Fiber (the portion of plants that cannot be digested by the human digestive tract) is classified as soluble and insoluble. Oats, beans, dried peas, and legumes are major sources of soluble fiber whereas wheat bran, whole grain products, and vegetables are major sources of insoluble fiber. Fruits, vegetables, and barley are sources of both insoluble and soluble fiber. Soluble fiber and insoluble fiber differ in function. For example, soluble fiber delays the time of transit through the intestine whereas insoluble fiber speeds up intestinal transit. For another example, soluble fiber and decreases the level of cholesterol in the blood whereas insoluble fiber has no effect on serum cholesterol.
Fibrates for lowering cholesterol
Fibrates are cholesterol-lowering drugs that are primarily effective in lowering triglycerides and, to a lesser extent, in increasing HDL-cholesterol levels.
Fibril
The diminutive of fiber. A small fiber, a fine thread.
Fibrillation, atrial
An abnormal irregular heart rhythm whereby electrical signals are generated chaotically throughout the upper chambers (atria) of the heart. Although many persons with atrial fibrillation have no symptoms, the most common symptom is palpitations, an uncomfortable awareness of the rapid and irregular heartbeat. Atrial fibrillation can cause blood clots that travel from the heart to the brain, causing stroke. Treatment of atrial fibrillation involves controlling the risk factors, medications to slow the heart rate and/or convert the heart to normal rhythm, and preventing complications of blood clotting.
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