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Fanconi anemia
Fanconi anemia A rare inherited type of aplastic anemia that is often but not always associated with skeletal abnormalities. Fanconi anemia carries an increased risk to the patient of developing acute myelogenous leukemia. The disorder may be treated by stem cell transplantation.
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Anemia
Anemia is a condition in which a deficiency in the size or number of erythrocytes (red blood cells) or the amount of hemoglobin they contain limits the exchange of oxygen and carbon dioxide between the blood and the tissue cells. Most anemias are caused by a lack of nutrients required for normal erythrocyte synthesis, principally iron, vitamin B-12, and folic acid. Others result from a variety of conditions, such as hemorrhage, genetic abnormalities, chronic disease states or drug toxicity.
Risk
In clinical trials, the probability of harm or discomfort for subjects, arising from the test product. Acceptable risk differs depending on the condition for which a product is being tested. A product for sore throat, for example, will be expected to have a low incidence of side effects. However, unpleasant side effects may be an acceptable risk when testing a promising treatment for a life-threatening illness.
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.
Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.
Transplantation
To transfer (tissue or an organ) from one body or body part to another.
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Free radical
Any molecule that contains an unpaired electron. Free radicals are unstable and will extract electrons from other biological molecules, which generates more free radicals.
Fetus
The stage of human development from 10 weeks' gestation until birth.
Fertilization
The combining of the genetic material carried by sperm and egg to create an embryo. Normally occurs inside the fallopian tube (in vivo) but may also occur in a petri dish (in vitro).
Fibromyalgia
Fibromyalgia is a debilitating chronic syndrome (constellation of signs and symptoms) characterized by diffuse pain, fatigue, and a wide range of other symptoms. It is not contagious, and recent studies suggest that people with fibromyalgia may be genetically predispose. It affects more women than men, with a ratio globally of 3-5:1. Fibromyalgia is seen in 3-10% of the general population, and is mostly found between the ages 20 and 50.
Farsightedness
Hyperopia occurs when the eyeball is too short from front to back, or the eye's focusing mechanism is too weak, causing light rays to be focused behind, rather than on the retina. People with hyperopia have difficulty seeing objects close up.
Fanconi anemia
Forensics
Forensics or forensic science is the application of science to questions which are of interest to the legal system. For example, forensic pathology is the study of the human body to determine cause and manner of death. Criminalistics is the application of various sciences to answer questions relating to examination and comparison of biological evidence, trace evidence, impression evidence, drugs and firearms. Forensic odontology is the study of the uniqueness of dentition. Etcetera.
Fibula
Smaller of the two bones in the lower leg; runs from the knee to the ankle along the outside of the lower leg.
Foot
The distal portion of the leg, upon which an individual stands and walks. It consists, in man, of the tarsus, metatarsus, and phalanges and the tissues encompassing them.
Fibrositis
Inflammation of fibrous connective tissues in muscles. It often affects the muscles of the trunk and back. It may be a symptom of another disease, such as Sciatica, but in most cases the cause is unknown. Pain and stiffness.
Fifth disease
Slapped cheek disease (erythema infectiosum) is also known as fifth disease because it was the last of five "red rash" childhood diseases to be defined after scarlet fever, measles, rubella, and roseola. It is characterised by fever and red cheeks.
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