Fab Immunoglobulins
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  Fab Immunoglobulins



Fab Immunoglobulins

   Antigen-binding fragments composed of one entire light chain and about half of one of the heavy chains, linked to each other by disulfide bonds. Fab contains the antigen binding site which is part of the variable region of the immunoglobulin molecule.

RELATED TERMS
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Antigen
A substance which, when present in animal tissue, stimulates the production of antibodies

Immunoglobulin
A serum protein involved in immunity. An antibody.



SIMILAR TERMS
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Fab 2
A fragment of an antibody containing two antigen-binding sites generated by cleavage of the antibody molecule with the enzyme pepsin which cuts at the hinge region C-terminally to the inter-H-chain disulphide bond.

Fab Fragments
Antigen-binding fragments composed of one entire light chain and about half of one of the heavy chains, linked to each other by disulfide bonds. Fab contains the antigen binding site which is part of the variable region of the immunoglobulin molecule.



PREVIOUS AND NEXT TERMS
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Fuzzy Logic
Approximate, quantitative reasoning that is concerned with the linguistic ambiguity which exists in natural or synthetic language. At its core are variables such as good, bad, and young as well as modifiers such as more, less, and very. These ordinary terms represent fuzzy sets in a particular problem. Fuzzy logic plays a key role in many medical expert systems.

Futility, Medical
The absence of a useful purpose or useful result in a diagnostic procedure or therapeutic intervention. The situation of a patient whose condition will not be improved by treatment or instances in which treatment preserves permanent unconsciousness or cannot end dependence on intensive medical care. (From Ann Intern Med 1990 Jun 15;112(12):949)

Fabricius Bursa
An epithelial outgrowth of the cloaca in birds similar to the thymus in mammals. It atrophies within 6 months after birth and remains as a fibrous remnant in adult birds. It is composed of lymphoid tissue and prior to involution, is the site of B-lymphocyte maturation.

Fabaviruses
A genus of the family COMOVIRIDAE with a wide host range among dicotyledons and some monocotyledons. They are transmitted nonpersistently by aphids. The type species is broad bean wilt virus 1.

Fabaceae
The large family of plants characterized by pods. Some are edible and some cause LATHYRISM; or FAVISM; and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various lectins like PHYTOHEMAGGLUTININ from PHASEOLUS. Many of them harbor nitrogen-fixing bacteria on their roots.

Fab Immunoglobulins

Face Peeling, Chemical
Application of a cauterant to the skin for the purpose of causing a superficial destruction of the epidermis and upper layers of the dermis. After healing, the treated area has new epithelium.

Face Lifts
Plastic surgery performed, usually by excision of skin, for the elimination of wrinkles from the skin.

Face Fly
A family of the order DIPTERA with over 700 species. Important species that may be mechanical vectors of disease include Musca domesticus (HOUSEFLIES), Musca autumnalis (face fly), Stomoxys calcitrans (stable fly), Haematobia irritans (horn fly) and Fannia spp.

Face
The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.

Facial Bone
The facial skeleton, consisting of bones situated between the cranial base and the mandibular region. While some consider the facial bones to comprise the hyoid, palatine, and zygomatic bones, mandible, and maxilla, others include also the lacrimal and nasal bones, inferior nasal concha, and vomer but exclude the hyoid bone. (Jablonski, Dictionary of Dentistry, 1992, p113)

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