Fab Fragments
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  Fab Fragments



Fab Fragments

   Antigen-binding fragments composed of one entire light chain and about half of one of the heavy chains, linked to each other by disulfide bonds. Fab contains the antigen binding site which is part of the variable region of the immunoglobulin molecule.

RELATED TERMS
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Antigen
A substance which, when present in animal tissue, stimulates the production of antibodies

Immunoglobulin
A serum protein involved in immunity. An antibody.



SIMILAR TERMS
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Fab 2
A fragment of an antibody containing two antigen-binding sites generated by cleavage of the antibody molecule with the enzyme pepsin which cuts at the hinge region C-terminally to the inter-H-chain disulphide bond.

Fab Immunoglobulins
Antigen-binding fragments composed of one entire light chain and about half of one of the heavy chains, linked to each other by disulfide bonds. Fab contains the antigen binding site which is part of the variable region of the immunoglobulin molecule.



PREVIOUS AND NEXT TERMS
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Fistula, Biliary
Abnormal passage in any organ of the biliary tract or between biliary organs and other organs.

Fistula, Arterio-Arterial
Abnormal communication between two arteries that may result from injury or occur as a congenital abnormality.

Fistula, Vaginal
An abnormal passage communicating with the vagina.

Fabry Disease
Lysosomal storage disease caused by a deficiency of alpha-galactosidase A and resulting in an accumulation of globotriaosylceramide in the renal and cardiovascular systems. The disease is X-linked and is characterized by telangiectatic skin lesions, renal failure, and disturbances of the cardiovascular, gastrointestinal, and central nervous systems.

Fabavirus
A genus of the family COMOVIRIDAE with a wide host range among dicotyledons and some monocotyledons. They are transmitted nonpersistently by aphids. The type species is broad bean wilt virus 1.

Fab Fragments

Face Pain
Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

Face Lift
Plastic surgery performed, usually by excision of skin, for the elimination of wrinkles from the skin.

Face Flies
A family of the order DIPTERA with over 700 species. Important species that may be mechanical vectors of disease include Musca domesticus (HOUSEFLIES), Musca autumnalis (face fly), Stomoxys calcitrans (stable fly), Haematobia irritans (horn fly) and Fannia spp.

Face Bows, Orthodontic
Extraoral devices for applying force to the dentition in order to avoid some of the problems in anchorage control met with in intermaxillary traction and to apply force in directions not otherwise possible.

Face Bow, Orthodontic
Extraoral devices for applying force to the dentition in order to avoid some of the problems in anchorage control met with in intermaxillary traction and to apply force in directions not otherwise possible.

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