FSH
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  FSH



FSH

   A gonadotropic hormone found in the anterior pituitary gland (PITUITARY GLAND, ANTERIOR) of mammals. It stimulates ovarian granulosa cells and testicular Sertoli cells, induces maturation of Graafian follicles in the ovary, and promotes the development of the germinal cells in the testis.

RELATED TERMS
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Hormone
A chemical substance formed in the body that is carried in the bloodstream to affect another part of the body; an example is thyroid hormone, produced by the thyroid gland in the neck, which affects growth, temperature regulation, metabolic rate, and other body functions.

Anterior
The front, as opposed to the posterior. The anterior surface of the heart is toward the breast bone (the sternum).

Pituitary
The gland from which a number of hormones are released into the bloodstream. These hormones include growth hormone, ACTH, B-lipocortin (the precursor to B-endorphorin), FSH, LH, and TSH.

Gland
An organ that releases a chemical. Endocrine glands are ductless and secrete hormones directly into the bloodstream. Exocrine glands secrete externally, either through a tube or duct.

Follicles
Each month several of these small egg-containing cavities develop on the ovary of an ovulating woman. Each cavity contains a single immature egg; ovulation occurs when a follicle (or sometimes more than one) ruptures and releases an egg.

Ovary
The female sex gland that contains ova, or eggs.

Development
The process of growth and differentiation.

Testis
(plural testes). A male's testes are located in a pouch that hangs suspended outside his body. The testes produce testosterone and sperm.



SIMILAR TERMS
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FSH Releasing Protein
Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

FSH Releasing Hormone
A decapeptide hormone released by the hypothalamus. It stimulates the synthesis and secretion of both FOLLICLE STIMULATING HORMONE and luteinizing hormone (LH) from the pituitary gland.

FSH Receptors
Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells.

FSH Receptor
Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells.

FSH alpha
A non-covalently bound subunit of the glycoprotein hormones TSH; FOLLICLE STIMULATING HORMONE; LH; and HCG which originates in the anterior pituitary gland and placenta. This subunit is virtually identical in structure and indistinguishable by radioimmunoassay in all of the above glycoproteins. It is present in both men and women, but is elevated in postmenopausal women and in patients with hypothyroidism, uremia and malignant tumors. The alpha subunit may be involved directly in recognition of certain receptors.

FSH

Frustration
The motivational and/or affective state resulting from being blocked, thwarted, disappointed or defeated.

Fucosidase Deficiency Diseases
An autosomal recessive lysosomal storage disease caused by a deficiency of ALPHA-L-FUCOSIDASE activity resulting in an accumulation of fucose containing SPHINGOLIPIDS, GLYCOPROTEINS, and mucopolysaccharides (GLYCOSAMINOGLYCANS) in lysosomes. The infantile form (type I) features psychomotor deterioration, MUSCLE SPASTICITY, coarse facial features, growth retardation, skeletal abnormalities, visceromegaly, SEIZURES, recurrent infections, and MACROGLOSSIA, with death occurring in the first decade of life. Juvenile fucosidosis (type II) is the more common variant and features a slowly progressive decline in neurologic function and angiokeratoma corporis diffusum. Type II survival may be through the fourth decade of life. (From Menkes, Textbook of Child Neurology, 5th ed, p87; Am J Med Genet 1991 Jan;38(1):111-31)

Fucosidase Deficiency Disease
An autosomal recessive lysosomal storage disease caused by a deficiency of ALPHA-L-FUCOSIDASE activity resulting in an accumulation of fucose containing SPHINGOLIPIDS, GLYCOPROTEINS, and mucopolysaccharides (GLYCOSAMINOGLYCANS) in lysosomes. The infantile form (type I) features psychomotor deterioration, MUSCLE SPASTICITY, coarse facial features, growth retardation, skeletal abnormalities, visceromegaly, SEIZURES, recurrent infections, and MACROGLOSSIA, with death occurring in the first decade of life. Juvenile fucosidosis (type II) is the more common variant and features a slowly progressive decline in neurologic function and angiokeratoma corporis diffusum. Type II survival may be through the fourth decade of life. (From Menkes, Textbook of Child Neurology, 5th ed, p87; Am J Med Genet 1991 Jan;38(1):111-31)

Fucose, GDP
A nucleoside diphosphate sugar formed from GDPmannose, which provides fucose for lipopolysaccharides of bacterial cell walls, and for blood group substances and other glycoproteins.

Fucose, Guanosine Diphosphate
A nucleoside diphosphate sugar formed from GDPmannose, which provides fucose for lipopolysaccharides of bacterial cell walls, and for blood group substances and other glycoproteins.

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