FSH-alpha
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  FSH-alpha



FSH-alpha

   A non-covalently bound subunit of the glycoprotein hormones TSH; FOLLICLE STIMULATING HORMONE; LH; and HCG which originates in the anterior pituitary gland and placenta. This subunit is virtually identical in structure and indistinguishable by radioimmunoassay in all of the above glycoproteins. It is present in both men and women, but is elevated in postmenopausal women and in patients with hypothyroidism, uremia and malignant tumors. The alpha subunit may be involved directly in recognition of certain receptors.

RELATED TERMS
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Glycoprotein
Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.

Hormones
Biological compounds that communicate information at a distance. Hormones require specific receptors to begin their biological action and use second messengers to initiate the cellular process that uses that information.

TSH
Thyroid-stimulating hormone. A pituitary hormone that stimulates thyroid hormone production.

FOLLICLE
The tiny shaft in the skin through which a hair grows, and sebum is excreted from sebaceous glands to the surface of the skin.

HORMONE
A chemical substance formed in the body that is carried in the bloodstream to affect another part of the body; an example is thyroid hormone, produced by the thyroid gland in the neck, which affects growth, temperature regulation, metabolic rate, and other body functions.

Anterior
The front, as opposed to the posterior. The anterior surface of the heart is toward the breast bone (the sternum).

Pituitary
The gland from which a number of hormones are released into the bloodstream. These hormones include growth hormone, ACTH, B-lipocortin (the precursor to B-endorphorin), FSH, LH, and TSH.

Gland
An organ that releases a chemical. Endocrine glands are ductless and secrete hormones directly into the bloodstream. Exocrine glands secrete externally, either through a tube or duct.

Placenta
Organ that grows in the uterus during pregnancy and connects the blood supplies of the mother and baby.

Glycoproteins
Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.

Hypothyroidism
Deficiency of thyroid hormone; the opposite of hyperthyroidism. The thyroid gland is in the throat, near the larynx or Adam's apple.

Uremia
The buildup in the blood of substances normally eliminated in the urine.

Malignant
Cancerous; life-threatening.

Receptors
Areas on the outer part of a cell that allow the cell to join or bind with insulin that is in the blood.



SIMILAR TERMS
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FSH-Releasing Hormone
A decapeptide hormone released by the hypothalamus. It stimulates the synthesis and secretion of both FOLLICLE STIMULATING HORMONE and luteinizing hormone (LH) from the pituitary gland.

FSH-Releasing Protein
Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.



PREVIOUS AND NEXT TERMS
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Fructosemonophosphate Aldolase
An enzyme of the lyase class that catalyzes the cleavage of fructose 1,6-biphosphate to form dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. The enzyme also acts on (3S,4R)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. (Enzyme Nomenclature, 1992) E.C. 4.1.2.13.

FT-207
Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.

FT 207
Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.

FSH-Releasing Hormone
A decapeptide hormone released by the hypothalamus. It stimulates the synthesis and secretion of both FOLLICLE STIMULATING HORMONE and luteinizing hormone (LH) from the pituitary gland.

FSH, Human
A gonadotropic hormone found in the anterior pituitary gland (PITUITARY GLAND, ANTERIOR) of mammals. It stimulates ovarian granulosa cells and testicular Sertoli cells, induces maturation of Graafian follicles in the ovary, and promotes the development of the germinal cells in the testis.

FSH-alpha

FSH, alpha Subunit
A non-covalently bound subunit of the glycoprotein hormones TSH; FOLLICLE STIMULATING HORMONE; LH; and HCG which originates in the anterior pituitary gland and placenta. This subunit is virtually identical in structure and indistinguishable by radioimmunoassay in all of the above glycoproteins. It is present in both men and women, but is elevated in postmenopausal women and in patients with hypothyroidism, uremia and malignant tumors. The alpha subunit may be involved directly in recognition of certain receptors.

FSH Releasing Protein
Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

FSH Releasing Hormone
A decapeptide hormone released by the hypothalamus. It stimulates the synthesis and secretion of both FOLLICLE STIMULATING HORMONE and luteinizing hormone (LH) from the pituitary gland.

FSH Receptors
Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells.

FSH Receptor
Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells.

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