Exacerbation
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  Exacerbation



Exacerbation

   A worsening. In medicine, exacerbation may refer to an increase in the severity of a disease or its signs and symptoms. For example, exacerbation of asthma is one of the serious effects of air pollution.

RELATED TERMS
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Exacerbation
A worsening. In medicine, exacerbation may refer to an increase in the severity of a disease or its signs and symptoms. For example, exacerbation of asthma is one of the serious effects of air pollution.

Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Asthma
Asthma is a chronic, inflammatory lung disease characterized by recurrent breathing problems. People with asthma have acute episodes or when the air passages in their lungs get narrower, and breathing becomes more difficult. Sometimes episodes of asthma are triggered by allergens, although infection, exercise, cold air and other factors are also important triggers.



SIMILAR TERMS
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Exacerbate
Cause something to increase in severity. To make more intense, irritate.



PREVIOUS AND NEXT TERMS
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Evolution
The continuing process of change, especially in reference to natural selection.

Evolution, biologic
Biologic evolution was contrasted with cultural (social) evolution in 1968 by A.G. Motulsky who pointed out that biologic evolution is mediated by genes, shows a slow rate of change, employs random variation (mutations) and selection as agents of change, new variants are often harmful, these new variants are transmitted from parents to offspring, the mode of transmission is simple, complexity is achieved by the rare formation of new genes by chromosome duplication, biologic evolution occurs with all forms of life, and the biology of humans requires cultural evolution.

Evolutionarily conserved gene
A gene that has remained essentially unchanged throughout evolution. Conservation of a gene indicates that it is unique and essential. There is not an extra copy of that gene with which evolution can tinker. And changes in the gene are likely to be lethal.

Evolutionarily conserved sequence
A base sequence in a DNA molecule (or an amino acid sequence in a protein) that has remained largely unchanged throughout evolution.

Ewing sarcoma
A type of bone tumor that occurs in children and adolescents, most often in the large bones of the arms and legs and the flat bones of the pelvis, spine and ribs. The tumor is caused by a chromosome abnormality, called a translocation (an exchange of material), most commonly between chromosomes 11 and 22 that occurs by chance alone in a single cell which divides to form the malignant clone (colony) of cells.

Exacerbation

Exaggerated startle disease
A genetic disorder also known as hyperexplexia in which babies have an exaggerated startle reflex (reaction).

Examination, digital rectal (DRE)
An exam done to detect abnormalities that can be felt (palpated) from within the rectum. The doctor inserts a lubricated, gloved finger into the rectum and feels for anything that is not normal. The digital rectal exam is an important screening test for the detection of tumors of the rectum and prostate abnormalities, including benign enlargement of the prostate (benign prostatic hyperplasia) and cancer of the prostate.

Examination, postmortem
An autopsy. Also called a necropsy.

Exanthem subitum
Means a sudden rash. A viral disease of infants and young children with sudden onset of high fever which lasts several days and then suddenly subsides leaving in its wake a fine red rash. The causative agent is herpesvirus type 6 so the disease is known as Sixth Disease. Also called Pseudorubella, Roseola, Roseola infantilis, and Roseola infantum.

Excess iron
Iron overload can damage the heart, liver, gonads and other organs. Iron overload is a particular risk for: People with certain genetic conditions such as hemochromatosis; and People receiving repeated blood transfusions.

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