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Evolutionarily conserved gene
Evolutionarily conserved gene A gene that has remained essentially unchanged throughout evolution. Conservation of a gene indicates that it is unique and essential. There is not an extra copy of that gene with which evolution can tinker. And changes in the gene are likely to be lethal.
RELATED TERMS--------------------------------------
Gene
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.
Evolution
The continuing process of change, especially in reference to natural selection.
Essential
1. Something that cannot be done without. 2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid. 3. Idiopathic. As in essential hypertension.
SIMILAR TERMS--------------------------------------
Evolution
The continuing process of change, especially in reference to natural selection.
Evolution, biologic
Biologic evolution was contrasted with cultural (social) evolution in 1968 by A.G. Motulsky who pointed out that biologic evolution is mediated by genes, shows a slow rate of change, employs random variation (mutations) and selection as agents of change, new variants are often harmful, these new variants are transmitted from parents to offspring, the mode of transmission is simple, complexity is achieved by the rare formation of new genes by chromosome duplication, biologic evolution occurs with all forms of life, and the biology of humans requires cultural evolution.
Evolutionarily conserved sequence
A base sequence in a DNA molecule (or an amino acid sequence in a protein) that has remained largely unchanged throughout evolution.
PREVIOUS AND NEXT TERMS--------------------------------------
Evert
To turn outward or turn inside out. To evert the foot is to move its forepart away from the midline of the body. To evert a hollow organ is to turn it inside out.
Evertor
A muscle that turns a part toward the outside. To evert is to turn outward or turn inside out.
Evidence-based medicine
The judicious use of the best current evidence in making decisions about the care of the individual patient. Evidence-based medicine (EBM) is mean to integrate clinical expertise with the best available research evidence and patient values.
Evolution
The continuing process of change, especially in reference to natural selection.
Evolution, biologic
Biologic evolution was contrasted with cultural (social) evolution in 1968 by A.G. Motulsky who pointed out that biologic evolution is mediated by genes, shows a slow rate of change, employs random variation (mutations) and selection as agents of change, new variants are often harmful, these new variants are transmitted from parents to offspring, the mode of transmission is simple, complexity is achieved by the rare formation of new genes by chromosome duplication, biologic evolution occurs with all forms of life, and the biology of humans requires cultural evolution.
Evolutionarily conserved gene
Evolutionarily conserved sequence
A base sequence in a DNA molecule (or an amino acid sequence in a protein) that has remained largely unchanged throughout evolution.
Ewing sarcoma
A type of bone tumor that occurs in children and adolescents, most often in the large bones of the arms and legs and the flat bones of the pelvis, spine and ribs. The tumor is caused by a chromosome abnormality, called a translocation (an exchange of material), most commonly between chromosomes 11 and 22 that occurs by chance alone in a single cell which divides to form the malignant clone (colony) of cells.
Exacerbation
A worsening. In medicine, exacerbation may refer to an increase in the severity of a disease or its signs and symptoms. For example, exacerbation of asthma is one of the serious effects of air pollution.
Exaggerated startle disease
A genetic disorder also known as hyperexplexia in which babies have an exaggerated startle reflex (reaction).
Examination, digital rectal (DRE)
An exam done to detect abnormalities that can be felt (palpated) from within the rectum. The doctor inserts a lubricated, gloved finger into the rectum and feels for anything that is not normal. The digital rectal exam is an important screening test for the detection of tumors of the rectum and prostate abnormalities, including benign enlargement of the prostate (benign prostatic hyperplasia) and cancer of the prostate.
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