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Evidence-based medicine
Evidence-based medicine The judicious use of the best current evidence in making decisions about the care of the individual patient. Evidence-based medicine (EBM) is mean to integrate clinical expertise with the best available research evidence and patient values.
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Mean The sum of the values of all observations or data points divided by the number of observations, an arithmetical average.
Clinical That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.
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EVAR Endovascular aneurysm repair. A procedure to repair an aneurysm of the aorta. In EVAR a stent is placed in the aneurysmal area of the aorta. The procedure is similar to the placement of a stent in a coronary artery after angioplasty. An aortic aneurysm is a ballooning or widening of the aorta, the largest artery in the body. The aneurysm weakens the wall of the aorta and can end in the aorta rupturing with catastrophic consequences. As the diameter of the aneurysm increases, the chances of the aneurysm rupturing rise dramatically. Large aortic aneurysms are very perilous and can be silent, with few or no symptoms. Men over 60 are particularly at risk to have an aortic aneurysm.
Evening primrose oil A natural source of essential fatty acids (EFOs). Evening primrose oil contains a higher level of arachnoidic acid than some other EFO sources, so people with seizure disorders may wish to avoid its use.
Event A set of outcomes. Cardiovascular events might include a heart attack and gastrointestinal events a GI bleed. The use of the term "event" in medicine comes from probability theory.
Evert To turn outward or turn inside out. To evert the foot is to move its forepart away from the midline of the body. To evert a hollow organ is to turn it inside out.
Evertor A muscle that turns a part toward the outside. To evert is to turn outward or turn inside out.
Evidence-based medicine
Evolution The continuing process of change, especially in reference to natural selection.
Evolution, biologic Biologic evolution was contrasted with cultural (social) evolution in 1968 by A.G. Motulsky who pointed out that biologic evolution is mediated by genes, shows a slow rate of change, employs random variation (mutations) and selection as agents of change, new variants are often harmful, these new variants are transmitted from parents to offspring, the mode of transmission is simple, complexity is achieved by the rare formation of new genes by chromosome duplication, biologic evolution occurs with all forms of life, and the biology of humans requires cultural evolution.
Evolutionarily conserved gene A gene that has remained essentially unchanged throughout evolution. Conservation of a gene indicates that it is unique and essential. There is not an extra copy of that gene with which evolution can tinker. And changes in the gene are likely to be lethal.
Evolutionarily conserved sequence A base sequence in a DNA molecule (or an amino acid sequence in a protein) that has remained largely unchanged throughout evolution.
Ewing sarcoma A type of bone tumor that occurs in children and adolescents, most often in the large bones of the arms and legs and the flat bones of the pelvis, spine and ribs. The tumor is caused by a chromosome abnormality, called a translocation (an exchange of material), most commonly between chromosomes 11 and 22 that occurs by chance alone in a single cell which divides to form the malignant clone (colony) of cells.
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