Ergotamine
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  Ergotamine



Ergotamine

    A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine.

RELATED TERMS
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Ergot
Ergot could be called a "cereal killer" for it comes from cereals such as rye and wheat and is quite capable of killing someone. A fungus (Claviceps purpurea) that contaminates rye and wheat produces substances (alkaloids) termed ergotamines. Ergotamines constrict blood vessels and cause the muscle of the uterus to contract. They have been much used and been very useful for the treatment of migraine. They have also been used and misused as abortifacients (agents of abortion).

Central
In anatomy and medicine (as elsewhere), central is the opposite of "peripheral" which means away from the center.

Alpha-1
Short for alpha-1 antitrypsin deficiency.

Adrenergic
This refers to neuronal or neurologic activity caused by neurotransmitters such as epinephrine, norepinephrine, and dopamine.

Agonist
Drug that increases neurotransmitter activity by stimulating the dopamine receptors directly.

Migraine
A vascular headache associated with changes in the size of the arteries within and outside of the brain. A migraine begins when hyperactive nerve cells send out impulses to the blood vessels, causing constriction, followed by the dilation of these vessels and the release of prostaglandins, serotonin, and other inflammatory substances that cause the pulsation to be painful. Migraine is a genetic disorder that is inherited. A migraine causes mild to severe pain and lasts from 4 hours up to a week. Migraines usually occur 2 to 4 times per month.



SIMILAR TERMS
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Ergoloid mesylates
Ergoloid mesylates is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ergoloid mesylates.

Ergomar
Ergomar is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ergotamine tartrate.

Ergonomics
The science of designing, building or equipping mechanical devices or artificial environments to the anthropometric, physiological, or psychological requirements of the people who will use them.

Ergophobia
An abnormal and persistent fear of work. Sufferers of ergophobia experience undue anxiety about the workplace environment even though they realize their fear is irrational. Their fear may actually be a combination of fears, such fear of failing at assigned tasks, fear of speaking before groups at work, or fear of socializing with co-workers.

Ergostat
Ergostat is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ergotamine tartrate.

Ergot
Ergot could be called a "cereal killer" for it comes from cereals such as rye and wheat and is quite capable of killing someone. A fungus (Claviceps purpurea) that contaminates rye and wheat produces substances (alkaloids) termed ergotamines. Ergotamines constrict blood vessels and cause the muscle of the uterus to contract. They have been much used and been very useful for the treatment of migraine. They have also been used and misused as abortifacients (agents of abortion).

Ergotamine tartrate and caffeine
Ergotamine tartrate and caffeine is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): caffeine; ergotamine tartrate.

Ergotism
Ergotism could be called a "cereal killer" for its cause, ergot, comes from cereals such as rye and wheat and is quite capable of killing someone. A fungus (Claviceps purpurea) that contaminates rye and wheat produces substances (alkaloids) termed ergotamines.



PREVIOUS AND NEXT TERMS
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Etizolam
A tranquilizer.

Ethenzamide
An analgesic and antipyretic medication.

Estazolam
A hypnotic substance.

Eremothecium
An order of fungi in the phylum Ascomycota that multiply by budding. They include the telomorphic ascomycetous yeasts which are found in a very wide range of habitats.

Ergonomics
The science of designing, building or equipping mechanical devices or artificial environments to the anthropometric, physiological, or psychological requirements of the people who will use them.

Ergotamine

Ercalcidiol
Biologically active metabolite of vitamin D2 which is more active in curing rickets than its parent. The compound is believed to attach to the same receptor as vitamin D2 and 25-hydroxyvitamin D3.

Endometriosis
A condition in which tissue more or less perfectly resembling the uterine mucous membrane (the endometrium) and containing typical endometrial granular and stromal elements occurs aberrantly in various locations in the pelvic cavity.

Enchancing antibodies
Antibodies which enhance the survival of a graft or of a tumour.

Enzyme-linked immunosorbent assay (ELISA)
An assay in which an enzyme is linked to an antibody and a coloured substrate is used to measure the activity of bound enzyme and, hence, the amount of bound antibody.

Eosinophil
A polymorphonuclear leukocyte with large eosinophilic (i.e. red) cytoplasmic granules.

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