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Eosinophil chemotactic factor of anaphylaxis (ECF-A)
Eosinophil chemotactic factor of anaphylaxis (ECF-A) A substrate released from mast cells during anaphylaxis which attracts eosinophils.
RELATED TERMS--------------------------------------
Anaphylaxis
Immediate hypersensitivity response to antigenic challenge, mediated by IgE and mast cells. It is a life-threatening allergic reaction, caused by the release of pharmacologically active agents.
SIMILAR TERMS--------------------------------------
Eosinophil
A polymorphonuclear leukocyte with large eosinophilic (i.e. red) cytoplasmic granules.
Eosinophilia
An abnormally high number of eosinophils in the blood. Normally, eosinophils constitute 1 to 3% of the peripheral blood leukocytes, at a count of 350 to 650 per cubic millimeter. Eosinophilia can be categorized as mild (less than 1500 eosinophils per cubic millimeter), moderate (1500 to 5000 per cubic millimeter), or severe (more than 5000 per cubic millimeter).
Eosinophilia-myalgia syndrome
Resembles eosinophilic fasciitis - due to L-Tryptophan.
Eosinophilic fasciitis
A scleroderma-like condition in which there is skin thickening and tethering with oedema along with thickening of the sub-epidermal fascia and infiltration with eosinophils. (Shulman's syndrome)
Eosinophilic gastroenteritis
Infection and swelling of the lining of the stomach, small intestine, or large intestine. The infection is caused by white blood cells (eosinophils).
Eosinophilic granuloma
A form of Histiocytosis-X. A rare cause of back pain in adolescence which may cause vertebral collapse.
Eosinophilic meningitis
Meningitis with a high percentage of eosinophils (a type of white blood cell) in the cerebrospinal fluid (CSF). The usual cause is the parasite Angiostrongylus cantonensis, also known as the rat lungworm. People become infected with this parasite by ingesting its larvae in raw or insufficiently cooked snails, slugs, freshwater prawns, frogs, or fish. Infection may also occur by consumption of fresh produce such as contaminated lettuce. When the larvae are ingested, they penetrate the intestinal tract, go into blood vessels, and eventually reach the meninges (the covering of the brain and spinal cord). The larvae usually die there shortly thereafter. An eosinophilic reaction develops in response to the dying larvae. It is manifested by an outpouring of eosinophils in the CSF.
PREVIOUS AND NEXT TERMS--------------------------------------
Ercalcidiol
Biologically active metabolite of vitamin D2 which is more active in curing rickets than its parent. The compound is believed to attach to the same receptor as vitamin D2 and 25-hydroxyvitamin D3.
Endometriosis
A condition in which tissue more or less perfectly resembling the uterine mucous membrane (the endometrium) and containing typical endometrial granular and stromal elements occurs aberrantly in various locations in the pelvic cavity.
Enchancing antibodies
Antibodies which enhance the survival of a graft or of a tumour.
Enzyme-linked immunosorbent assay (ELISA)
An assay in which an enzyme is linked to an antibody and a coloured substrate is used to measure the activity of bound enzyme and, hence, the amount of bound antibody.
Eosinophil
A polymorphonuclear leukocyte with large eosinophilic (i.e. red) cytoplasmic granules.
Eosinophil chemotactic factor of anaphylaxis (ECF-A)
Epitope
An alternative term for antigenic determinant.
Equivalence zone
In a precipitin reaction, the region in which the concentration of antigen and antibody leads to maximal precipitation.
Exon
The region of DNA coding for a protein or a segment of a protein.
Effeminate
A womanish or sissyish manner and bearing in a man or boy stigmatized as an unmanly homosexual.
Ego dystonic
In psychiatry, the term used to apply to a proclivity, for example, toward homosexuality, in a person who seeks to repudiate it.
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