Douglas, pouch of

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Douglas, pouch of

Douglas, pouch of

An extension of the peritoneal cavity between the rectum and back wall of the uterus. The term "cul-de-sac," aside from being any "blind pouch or cavity that is closed at one end," is used specifically to refer to the rectouterine pouch.

RELATED TERMS
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Extension
The process of straitening or the state of being strait. Extension of the hip and knee joints is necessary to stand up from the sitting position.

Peritoneal
Having to do with the peritoneum (the tissue that lines the abdominal wall and covers most of the organs in the abdomen).

Cavity
A hollow place or hole within the body.

Rectum
An 8-inch chamber connected to the large intestine that receives solid waste (feces) from the descending colon to be expelled from the body. The rectum connects the colon to the anus. It is the rectum's job to receive stool from the colon, to let the person know that there is stool to be evacuated, and to hold the stool until evacuation happens.

Uterus
The uterus is a hollow, pear-shaped organ located in a woman's lower abdomen, between the bladder and the rectum, that sheds its lining each month during menstruation and in which a fertilized egg (ovum) becomes implanted and the fetus develops.

SIMILAR TERMS
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Douglas doctors
All doctors near Douglas, the Isle of Man. Doctors who can assist a patient in Douglas.

Douglas Hospital
The Douglas Hospital is a hospital in Montreal, Quebec, Canada.

PREVIOUS AND NEXT TERMS
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Double pneumonia
Inflammation of both lungs. Medically called bilateral pneumonia.

Double-blind
Term used to described a study in which both the investigator or the participant are blind to (unaware of) the nature of the treatment the participant is receiving. Double-blind trials are thought to produce objective results, since the expectations of the researcher and the participant about the experimental treatment such as a drug do not affect the outcome. Also called double-masked.

Double-blinded study
A study in which at least two separate groups receive the experimental medication or procedure at different times, with neither group being made aware of when the experimental treatment or procedure has been given. Double-blinded studies are often chosen when a treatment shows particular promise and the illness involved is serious. It can be hard to recruit human subjects for a blinded study of a promising treatment when one group will receive only a placebo or an existing medicine.

Double-jointed
Popular term to describe a joint that is unusually flexible. Medically, the joint is said to be hyperflexible, hyperextensible, or hypermobile. People whose fingers are hypermobile have lower rates of arthritis in the hands.

Douching
Using water or a medicated solution to clean the vagina. Vaginal douching has been done for many, many years. However, there is currently concern that it may sometimes cause problems. It may mask, or even worsen, conditions such as bacterial or yeast infection of the vagina. Even more seriously, douching is associated with an increased risk of pelvic inflammatory disease (PID). It is also associated with an increased risk of an ectopic pregnancy (probably due to PID). The American College of Obstetricians and Gynecologists (ACOG) recommends against douching.

Douglas, pouch of

Down syndrome critical region
(Abbreviated DSCR) A region on the long (q) arm of chromosome 21 thought to be responsible for some, if not all, of the features of Down syndrome. A number of genes in this region may be involved in the production of the Down syndrome phenotype. These genes may include the Down syndrome critical region 1 gene or DSCR1 on chromosome 22q11.2; DSCR2 on chromosome 21q22.3; DSCR3 in chromosome 21q22.2; DSCR4 on chromosome 21q22.2; and DSCR5 in chromosome region 21q22.1-q22.2.

Down syndrome features
Children with Down syndrome have multiple malformations and mental impairment due to the presence of extra material from chromosome 21. Among the more common physical features are hypotonia (floppiness), small head with brachycephaly, epicanthic folds across the inside corners of the eyes, upward outward slanting palpebral fissures (eye slits), Brushfield spots in the iris, small mouth, small ears, excessive skin at the nape of the neck, a single transverse palmar crease, and short fifth finger with clinodactyly (incurving). A wide space, often with a deep fissure between the first and second toes, is also common. There is an increased risk of congenital heart defects (50%); leukemia (<1%); hearing loss (75%); otitis media (ear infections) (50%-70%); Hirschsprung disease with absence of nerves from the bowel (<1%); gastrointestinal atresia (12%); eye disease (60%), including cataracts (15%) and severe refractive errors (50%); acquired hip dislocation (6%); obstructive sleep apnea (50%-75%); and thyroid disease (15%). There is no increased risk of solid tumors.

Downregulation
An decrease in the number of receptors on the surface of target cells, making the cells less sensitive to a hormone or another agent. Some receptors can be rapidly down regulated.

Doxorubicin cardiomyopathy
Heart disease due to the drug doxorubicin (brand name:Adriamycin), a potent broad-spectrum antitumor agent effective in treating a variety of cancers including solid tumors and leukemia. Unfortunately, its clinical use is limited by dose-dependent cardiac side effects that lead to degenerative cardiomyopathy, congestive heart failure, and death. In addition, some adult patients treated with the drug when they were children later develop dilated cardiomyopathy. Endocardial biopsies from patients undergoing doxorubicin therapy reveal a disruption of myofibrils, impairment of microtubule assembly, and a swelling of the endoplasmic reticulum. Doxorubicin cardiotoxicity is also characterized by a dose-dependent decline in mitochondrial oxidative phosphorylation and a decrease in high-energy phosphate pools.

Doyne honeycomb retinal dystrophy
Abbreviated DHRD. An eye disease also known as malattia leventinese.

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This dictionary contains 25007 terms.

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