Discordance
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  Discordance



Discordance

   1. The presence of any given condition such as HIV in only one member of a couple. 2. In genetics, the presence of a phenotype such as asthma in only one members of a twin pair. 3. In clinical care, lack of agreement between physician and patient.In all sense, disconcordance is as opposed to concordance.

RELATED TERMS
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Condition
The term "condition" has a number of biomedical meanings including the following: 1.An unhealthy state, such as in "this is a progressive condition." 2.A state of fitness, such as "getting into condition." 3.Something that is essential to the occurrence of something else; essentially a "precondition." 4.As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Genetics
The scientific study of heredity. Genetics pertains to humans and all other organisms. So, for example, there is human genetics, mouse genetics, fruitfly genetics, etc.

Phenotype
The expression of the genes present in an individual. This may be directly observable (eye color) or apparent only with specific tests (blood type). Some phenotypes such as the blood groups are completely determined by heredity, while others are readily altered by environmental agents.

Asthma
Asthma is a chronic, inflammatory lung disease characterized by recurrent breathing problems. People with asthma have acute episodes or when the air passages in their lungs get narrower, and breathing becomes more difficult. Sometimes episodes of asthma are triggered by allergens, although infection, exercise, cold air and other factors are also important triggers.

Clinical
That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.

Physician
A doctor. An authorized practitioner of medicine.

Concordance
1. The presence of any given condition such as HIV in both members of a couple. 2. In genetics, the presence of a phenotype such as asthma in both members of a twin pair. 3. In clinical care, agreement between physician and patient.



SIMILAR TERMS
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Disc
Shortened terminology for an intervertebral disc, a disk-shaped piece of specialized tissue that separates the bones of the spinal column.

Disc prolapse
Condition in which an intervertebral disc is damaged and some of it protrudes. May cause sciatica if it does so in the vicinity of a major nerve in the spine.

Disc, cervical
A disk shaped piece of specialized tissue that separates the vertebral bones of the spinal column in the neck.

Disc, optic
The circular area in the back of the inside of the eye where the optic nerve connects to the retina. Also called the optic nerve head.

Disc, slipped
Rupturing of the tissue that separates the vertebral bones of the spinal column.

Discase
Discase is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): chymopapain.

Discharge
1.The flow of fluid from part of the body, such as from the nose or vagina. 2. The passing of an action potential, such as through a nerve or muscle fiber. 3. The release of a patient from a course of care. The doctor may then dictate a discharge summary.

Discipline
The limits a parent or caregiver sets on a child's behavior for purposes of safety or socialization.

Discoid lupus erythematosus
A round, red, scaling rash on the nose, forehead, cheeks, scalp or other areas of the body. It may be associated with systemic lupus erythematosus.

Disconnection syndrome
Term coined by Norman Geschwind to describe the interruption of information transferred from one brain region to another.

Discordant
1. Showing discordance, lack of agreement. A couple may be discordant for a sexually transmitted infection, with one partner having it and the other not. 2. In transplantation genetics, between different species. A discordant xenograft is a transplant between members of very different species

Discordant couple
A pair of long-term sexual partners in which one has a sexually transmitted infection and the other does not. The CDC has guidelines for counseling discordant couples in which the woman is HIV-infected and her husband is HIV-uninfected.

Discounting the illuminant
Illumination of the visual world tens to be non-uniform, and fluctuates. in order for the visual system to create a consistent perception of color and lightness it must somehow discount fluctuation and gradient in the lighting source.



PREVIOUS AND NEXT TERMS
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Disc
Shortened terminology for an intervertebral disc, a disk-shaped piece of specialized tissue that separates the bones of the spinal column.

Disc, cervical
A disk shaped piece of specialized tissue that separates the vertebral bones of the spinal column in the neck.

Disc, optic
The circular area in the back of the inside of the eye where the optic nerve connects to the retina. Also called the optic nerve head.

Disc, slipped
Rupturing of the tissue that separates the vertebral bones of the spinal column.

Discharge
1.The flow of fluid from part of the body, such as from the nose or vagina. 2. The passing of an action potential, such as through a nerve or muscle fiber. 3. The release of a patient from a course of care. The doctor may then dictate a discharge summary.

Discordance

Discordant
1. Showing discordance, lack of agreement. A couple may be discordant for a sexually transmitted infection, with one partner having it and the other not. 2. In transplantation genetics, between different species. A discordant xenograft is a transplant between members of very different species

Discordant couple
A pair of long-term sexual partners in which one has a sexually transmitted infection and the other does not. The CDC has guidelines for counseling discordant couples in which the woman is HIV-infected and her husband is HIV-uninfected.

Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Disease nomenclature
A system of classifying and naming diseases.

Disease surveillance
The ongoing systematic collection and analysis of data and the provision of information which leads to action being taken to prevent and control a disease, usually one of an infectious nature.

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