Defect, enzyme

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Defect, enzyme

Defect, enzyme

An abnormality in the protein (enzyme) important in catalyzing a normal biochemical reaction in the body. Disorders result from a deficiency (or functional abnormality) of an enzyme.

RELATED TERMS
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Protein
Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others.

Biochemical
Relating to biochemistry, the application of the tools and concepts of chemistry to living systems.

Enzyme
A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst.

SIMILAR TERMS
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Defecation
The passage of bowel contents through the rectum and anus.

Defecation syncope
The temporary loss of consciousness (syncope) upon defecating (having a bowel movement). Syncope is the temporary loss of consciousness or, in plain English, fainting. The situations that trigger this reaction are diverse and include having blood drawn, straining while urinating (micturition syncope) or defecating, coughing or swallowing. The reaction also can be due to the emotional stress of fear or pain.

Defect, atrial septal (ASD)
A hole in the septum, the wall, between the atria, the upper chambers of the heart. Commonly called an ASD. ASDs are a major class of congenital cardiac malformation.

Defect, neural tube
A major birth defect caused by abnormal development of the neural tube, the structure present during embryonic life which gives rise to the central nervous system - the brain and spinal cord. Neural tube defects (NTDs) are among the most common birth defects that cause infant mortality (death) and serious disability.

Defect, ventricular septal (VSD)
A hole in the septum (the wall) between the lower chambers of the heart (the ventricles).

Defeminization
The developmental process in which feminization is inhibited or suppressed. In females the term applies chiefly to defeminization of the brain attributed to a hormonal anomaly in prenatal life.

Defense mechanism
Automatic psychological process that protects the individual against anxiety and from awareness of internal or external stressors or dangers. Defense mechanisms mediate the individual's reaction to emotional conflicts and to external stressors. Some defense mechanisms (e.g., projection, splitting, and acting out) are almost invariably maladaptive. Others, such as suppression and denial, may be either maladaptive or adaptive, depending on their severity, their inflexibility, and the context in which they occur.

Defensin
A family of potent antibiotics made within the body by neutrophils (a type of white blood cell) and macrophages (cells that can engulf foreign particles). The defensins play important roles against invading microbes. They act against bacteria, fungi and viruses by binding to their membranes and increasing membrane permeability. On a chemical level, the defensins are small peptides unusually rich in the amino acid cysteine (Cys).The human defensins are classified into the alpha-defensins and beta-defensins on the basis of their sequence homology and their Cys residues.

Defensive medicine
Medical practices designed to avert the future possibility of malpractice suits. In defensive medicine, responses are undertaken primarily to avoid liability rather than to benefit the patient. Doctors may order tests, procedures, or visits, or avoid high-risk patients or procedures primarily (but not necessarily solely) to reduce their exposure to malpractice liability. Defensive medicine is one of the least desirable effects of the rise in medical litigation. Defensive medicine increases the cost of health care and may expose patients to unnecessary risks.

Deferoxamine mesylate
Deferoxamine mesylate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): deferoxamine mesylate .

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Deep vein thrombosis
A blood clot (thrombus) in a deep vein in the thigh or leg. The clot can break off as an embolus and make its way to the lung, where it can cause respiratory distress and respiratory failure.

Deer mouse
A deceptively cute rodent capable of carrying the types of hantavirus.

Deerfly fever
An infection in rabbits and other wild rodents caused by the bacterium Francisella tularensis that can be transmitted to humans by contact with infected animal tissues or ticks. Also called tularemia.

Defecation syncope
The temporary loss of consciousness (syncope) upon defecating (having a bowel movement). Syncope is the temporary loss of consciousness or, in plain English, fainting. The situations that trigger this reaction are diverse and include having blood drawn, straining while urinating (micturition syncope) or defecating, coughing or swallowing. The reaction also can be due to the emotional stress of fear or pain.

Defect, atrial septal (ASD)
A hole in the septum, the wall, between the atria, the upper chambers of the heart. Commonly called an ASD. ASDs are a major class of congenital cardiac malformation.

Defect, enzyme

Defect, neural tube
A major birth defect caused by abnormal development of the neural tube, the structure present during embryonic life which gives rise to the central nervous system - the brain and spinal cord. Neural tube defects (NTDs) are among the most common birth defects that cause infant mortality (death) and serious disability.

Defect, ventricular septal (VSD)
A hole in the septum (the wall) between the lower chambers of the heart (the ventricles).

Defensin
A family of potent antibiotics made within the body by neutrophils (a type of white blood cell) and macrophages (cells that can engulf foreign particles). The defensins play important roles against invading microbes. They act against bacteria, fungi and viruses by binding to their membranes and increasing membrane permeability. On a chemical level, the defensins are small peptides unusually rich in the amino acid cysteine (Cys).The human defensins are classified into the alpha-defensins and beta-defensins on the basis of their sequence homology and their Cys residues.

Defensive medicine
Medical practices designed to avert the future possibility of malpractice suits. In defensive medicine, responses are undertaken primarily to avoid liability rather than to benefit the patient. Doctors may order tests, procedures, or visits, or avoid high-risk patients or procedures primarily (but not necessarily solely) to reduce their exposure to malpractice liability. Defensive medicine is one of the least desirable effects of the rise in medical litigation. Defensive medicine increases the cost of health care and may expose patients to unnecessary risks.

Defibrillation
The use of a carefully controlled electric shock, administered either through a device on the exterior of the chest wall or directly to the exposed heart muscle, to restart or normalize heart rhythms.

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This dictionary contains 25007 terms.

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