D gene
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  D gene



D gene

    A small segment of immunoglobulin heavy-chain and T-cell receptor DNA, coding for the third hypervariable region of most receptors.

RELATED TERMS
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Immunoglobulin
A serum protein involved in immunity. An antibody.

T-cell
A white blood cell concerned with immunity. It does not produce antibodies.

Receptor
A molecule that recognizes a unique hormone. Once that hormone is bound to the receptor, the information carried by the hormone can now exert its biological action.

DNA
Deoxyribo-Nucleic acid. DNA molecules carry the genetic information necessary for the organization and functioning of most living cells and control the inheritance of characteristics.

Receptors
Areas on the outer part of a cell that allow the cell to join or bind with insulin that is in the blood.



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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D gene

Delayed type hypersensitivity (DTH)
A T cell-mediated reaction to antigen, which takes 24-48 hours to develop fully, and which involves release of lymphokines and recruitment of monocytes and macrophages. Also called c cell-mediated immunity.

Determinant
Part of the antigen molecule which binds to an antibody-combining site or to a receptor on T cells (see hapten and epitope).

Differentiation antigen
A cell surface antigenic determinant found only on cells of a certain lineage and at a particular developmental stage; used as an immunologic marker.

Domain
compact segment of an immunoglobulin molecule, made up of about 110 amino acids around an S-S bond, and encoded by a unique segment of DNA, surrounded by nontranslated sequences.

DR antigens
MHC class II molecules found on B cells and antigen-presenting cells of humans.

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