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DNS
DNS On a prescription, Do Not Substitute. If a physician orders a particular drug and writes DNS on the prescription, that tells the pharmacist not to substitute a generic version or any other drug for the prescribed drug.
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Prescription A prescription, as is well known, is a physician's order for the preparation and administration of a drug or device for a patient.
Physician A doctor. An authorized practitioner of medicine.
Pharmacist A person licensed to mix and dispense drugs.
Generic A drug not protected by a trademark. Also, the scientific name as opposed to the proprietary, brand name.
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DNA, coding A sequence of DNA that codes for protein. Coding DNA sequences are separated by long regions of DNA called introns that have no apparent function. Coding DNA is also known as an exon.
DNA, mitochondrial Mitochondrial DNA (mtDNA) is the DNA of the mitochondrion, a structure situated in the cytoplasm of the cell rather than in the nucleus (where all the other chromosomes are located). All mtDNA is inherited from the mother. There are 2 to 10 copies of the mtDNA genome in each mitochondrion. mtDNA is a double-stranded, circular molecule. It is very small relative to the chromosomes in the nucleus and so contains only a limited number of genes. It is specialized in the information it carries and encodes a number of the subunits in the mitochondrial respiratory-chain complex that the cell needs to respire. (It also contains genes for some ribosomal RNAs and transfer RNAs). Mutations (changes) in mtDNA can cause disease. The mutations often impair the function of oxidative-phosphorylation enzymes in the respiratory chain. This is especially manifest in tissues with a high energy expenditure such as brain and muscle.
DNA, repetitive DNA sequences that are repeated in the genome. These sequences do not code for protein. One class termed highly repetitive DNA consists of short sequences, 5-100 nucleotides, repeated thousands of times in a single stretch and makes up satellite DNA. Another class termed moderately repetitive DNA consists of longer sequences, about 150-300 nucleotides, dispersed evenly throughout the genome, and includes what are called Alu sequences and transposons.
DNA, satellite DNA that contains many tandem (not inverted) repeats of a short basic repeating unit. Satellite DNA is located at very specific spots in the genome (on chromosomes 1, 9, 16 and the Y chromosome, the tiny short arms of chromosomes 13-15 and 21 and 22, and near the centromeres of chromosomes).
DNR Do not resuscitate.
DNS
Do not resuscitate order A request not to have cardiopulmonary resuscitation (CPR) done if the heart stops or breathing ceases.
DOB Abbreviation standing for the date of birth.
DOC 1. Acronym for "daily on call." 2. Deoxycorticosterone.
Docosahexaenoic acid DHA. An essential fatty acid, thought to be important to the development of infants, particularly as regards their eyes and brain. DHA is present in breast milk and has been added to some infant formulas. Postnatal DHA may improve vision and some cognitive functions in infants and toddlers. DHA is an omega-3, polyunsaturated, 22-carbon fatty acid. It is present in abundance in certain fish (such as tuna and bluefish) and marine animal oils.
Dol A unit of measurement of pain. The term dol was invented by James Hardy and his research colleagues Herbert Wolff and Helen Goodell at Cornell University where from 1950 to 1959, they carried out pioneering experiments on pain. Hasrdy, Wolff and Goodell used precisely calibrated radiant heat directed to the foreheads or hands of trained experimental subjects. They asked the subjects to report each "just noticeable difference" in the intensity of pain they experienced, and graphed their responses on the "dol" scale, in which one dol equals two "just noticeable differences." The graphs showed the effectiveness of different analgesics in relieving the pain, and the physiologic responses with different intensities of pain. From the Latin word for pain, dolor.
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