DADPS
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  DADPS



DADPS

   A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

RELATED TERMS
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Bacteria
Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).

Mechanism
The arrangement or association of the elements or parts of anything in relation to the effect they generate; the combination of mental processes by which an effect is generated.

Malaria
A disease caused by a parasite that is transmitted person-to-person by the bite of an infected Anopheles mosquito. These mosquitoes are present in the tropics and subtropics in almost all countries. Malaria is the most deadly of all tropical parasitic diseases.



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Dace
A family of freshwater fish comprising the minnows or CARPS.

DA-dT, Poly
Polydeoxyribonucleotides made up of deoxyadenine nucleotides and thymine nucleotides. Present in DNA preparations isolated from crab species. Synthetic preparations have been used extensively in the study of DNA.

DA-2370
A pyrazole that has analgesic, anti-inflammatory, and antipyretic properties. It has been used in mild to moderate pain, fever, and inflammation associated with musculoskeletal and joint disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p15)

DAG Kinase
An enzyme of the transferase class that uses ATP to catalyze the phosphorylation of diacylglycerol to a phosphatidate. EC 2.7.1.107.

Daflon
A bioflavonoid that strengthens vascular walls.

DADPS

DADLE
A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.

DADDS
Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.

Dactylolysis Spontanea
Spontaneous autoamputation of the fourth or fifth toe.

Dactinomycin
An antitumor antibiotic derived from Streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

Dactarin
An imidazole antifungal agent that is used topically and by intravenous infusion.

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