D-dimer
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  D-dimer



D-dimer

   A fragment produced during the degradation of a clot. The D here stands for domain. Dimer indicates two identical units, in this case two identical domains. D-dimer result from complete breakdown of the clot. Monoclonal antibody to the D-dimer fragment provide the basis for the main methods of detecting it. The presence of D-dimers in the blood is a reliable clue that clotting has begun. Sometimes written d-dimer or D-Dimer. Pronounced deemer.

RELATED TERMS
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Clot
A jelly-like mass of blood.

Domain
compact segment of an immunoglobulin molecule, made up of about 110 amino acids around an S-S bond, and encoded by a unique segment of DNA, surrounded by nontranslated sequences.

D-dimer
A fragment produced during the degradation of a clot. The D here stands for domain. Dimer indicates two identical units, in this case two identical domains. D-dimer result from complete breakdown of the clot. Monoclonal antibody to the D-dimer fragment provide the basis for the main methods of detecting it. The presence of D-dimers in the blood is a reliable clue that clotting has begun. Sometimes written d-dimer or D-Dimer. Pronounced deemer.

Monoclonal
Literally, coming from a single clone. A clone is the progeny of a single cell. In immunology, monoclonal generally describes a preparation of antibody that is monogenous, or cells of a single specificity.

Antibody
An infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms (eg, bacteria, viruses) or toxins. Antibodies, known generally as immunoglobulins, are made and secreted by B-lymphocytes in response to stimulation by antigens. Each specific antibody binds only to the specific antigen that stimulated its production.

Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.

Clotting
The sealing of a blood vessel with coagulated blood.

D-Dimer
A fragment produced during the degradation of a clot. The D here stands for domain. Dimer indicates two identical units, in this case two identical domains. D-dimer result from complete breakdown of the clot. Monoclonal antibody to the D-dimer fragment provide the basis for the main methods of detecting it. The presence of D-dimers in the blood is a reliable clue that clotting has begun. Sometimes written d-dimer or D-Dimer. Pronounced deemer.



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Diastolic
The lower number in a blood pressure reading that indicates the pressure in the heart when the muscle is relaxed (the point of least pressure).

Dilated cardiomyopathy
A disease of the myocardium (heart muscle) that causes the heart cavity to become stretched and enlarged, and the pumping capacity of the heart is reduced.

Dilatation
The increase in size of a blood vessel.

DNR Order (Do Not Resuscitate Order)
An advanced directive that means no CPR is to be done when the heart and lungs stop.

Donor
A person who gives an organ, tissue or blood to another person. A compatible donor is a person who has the same tissue and blood types as the person who receives the organ, tissue or blood.

D-dimer

D-IBS
Diarrhea-predominant IBS (irritable bowel syndrome).

D O
Abbreviation for Doctor of Osteopathy, an osteopathic physician.

Dacry
Combining form used before a vowel to denote a relationship to tears.

Dacryo
A combining form denoting tears, as in dacryocyst (tear sac) and dacryocystorhinostomy (surgery to open up a tear duct).

Dacryoadenitis
Inflammation of a lacrimal gland (a gland that produces tears).

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