Corticosteroid drugs
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  Corticosteroid drugs



Corticosteroid drugs

    Anti-inflammatory drugs that interfere with the immune system, suppress it and thereby dampen the inflammatory overreaction. They can be used to treat a number of allergic diseases - e.g. allergic rhinitis, eczema and rheumatoid arthritis. Corticosteroid drugs come as creams, inhalants, tablets and eye drops.

RELATED TERMS
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Immune
Resistant to a particular disease.

Rhinitis
An inflammation of the mucous membrane that lines the nose, often due to allergy to pollen, dust or other airborne substances, which causes sneezing, itching, a runny nose and nasal congestion.

Eczema
A disorder of the skin like psoriasis and also considered to be related to malfunctions of the immune system. Symptoms include red, itchy skin and sores that ooze and crust over. One out of ten children develops eczema, but more than half of them lose it by the time they reach their teens.

Arthritis
Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. Arthritis occurs in various forms, such as the arthritis associated with infections, osteoarthritis, or rheumatoid arthritis. Many forms of vasculitis can also be associated with arthritis.

Corticosteroid
Hormones produced by the adrenal gland which are important to almost every function of cells and organs. They are divided into two groups: glucocorticoids and mineralocorticoids. Glucocorticoids regulate protein, carbohydrate, and fat metabolism. Mineralocorticoids regulate electrolyte balances.



SIMILAR TERMS
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Cort-dome
Cort-dome is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortalone
Cortalone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): prednisolone.

Cortan
Cortan is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): prednisone.

Cortef
Cortef is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortef acetate
Cortef acetate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone acetate.

Cortenema
Cortenema is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortex
The outer layer of the cerebrum, densely packed with nerve cells.

Cortex, adrenal
The outer portion of the adrenal gland located on top of each kidney. The adrenal cortex produces steroid hormones which regulate carbohydrate and fat metabolism and mineralocorticoid hormones which regulate salt and water balance in the body.

Cortical
Having to do with the cortex, the outer portion of an organ.

Cortical Blindness
A person with cortical blindness will have normal eyes and normal optic nerves but, nevertheless, will not be able to see. The cause of the blindness is with the cortex or surface of the brain that contains 32 or more sites for visual information processing. More recently, the preferred term for such individuals is cortical visual impairment, because many people will not be totally blind but will exhibit unusual visual losses; for example, they may be blind to stationary objects but be able to see moving objects.

Cortical blindness
Blindness due to loss or injury to the visual cortex, that section of the cerebral cortex responsible for vision, as through a stroke or traumatic brain damage.

Cortical magnification factor
Defined as millimeters of cortex per degree of visual angle.

Corticaltectal pathway
Pathway from the cortex to the superior colliculi.

Corticoids
Substances similar to the hormone of the adrenal glands called cortisone; corticoids are differentiated into two groups – mineralocorticoids and glucocorticoids applied both locally and systemically, mainly as anti-phlogistics, immunosuppressives, anti-asthmathics or in the treatment of an allergy.

Corticosteroid
Hormones produced by the adrenal gland which are important to almost every function of cells and organs. They are divided into two groups: glucocorticoids and mineralocorticoids. Glucocorticoids regulate protein, carbohydrate, and fat metabolism. Mineralocorticoids regulate electrolyte balances.

Corticosteroid allergy
A delayed allergic reaction to corticosteroid (drugs similar to cortisone). This occurs in 1-4% of people who use corticosteroids for asthma or other allergic diseases. A positive patch test to a corticosteroid means the patient cannot use that particular steroid. Although cross allergy between corticosteroids is common, such patients usually can tolerate another corticosteroid.

Corticosteroid hormones
Hormones produced by the adrenal glands.

Corticosteroids
Sometimes referred to just as 'steroids'. Hormones (which occur naturally) which have a variety of actions when given therapeutically. Usually administered for their anti-inflammatory effect. Their use is limited by unwanted side-effects which may sometimes be serious.

Corticotropin
Corticotropin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): corticotropin.

Corticotropin-releasing hormone
A hormone made by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland. Corticotropin-releasing hormone is abbreviated and often referred to as CRH.

Corticotropin-Releasing Hormone (CRH)
The hormone released from the hypothalamus. It interacts with the pituitary to produce ACTH. This hormone uses cyclic AMP for its second messenger.

Cortifoam
Cortifoam is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone acetate.

Cortisol
The hormone released from the adrenal glands in response to stress or low blood glucose. Its primary mode of action in times of stress is to shut down eicosanoid synthesis. Its synthesis in the adrenal gland requires the second messenger, cyclic AMP.

Cortisone
An adrenocorticoid hormone, a naturally occurring hormone made by and secreted by the adrenal cortex, the outer part (the cortex) of the adrenal gland.

Cortisone acetate
Cortisone acetate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cortisone acetate.

Cortisporin
Cortisporin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): bacitracin zinc; hydrocortisone; neomycin sulfate; polymyxin b sulfate.

Cortone
Cortone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cortisone acetate.

Cortril
Cortril is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortrophin-zinc
Cortrophin-zinc is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): corticotropin-zinc hydroxide.

Cortrosyn
Cortrosyn is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cosyntropin.



PREVIOUS AND NEXT TERMS
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Cystourethrocele
Condition that results when the urethra and its supporting tissues weaken and drop into the vagina leading to stress incontinence.

Castration
The surgical removal of the testicles.

Causal treatment
A form of treatment which deals with the cause of a disease, not only the symptoms. Specific allergy vaccination is a causal treatment, the use of antihistamines is a symptomatic treatment.

Cell memory
If foreign substances (e.g. bacteria) enter the body, the immune system reacts by attacking and killing them. At the same time, T-cells and B-cells produce a population of memory cells. If you are subsequently exposed to the same bacteria, the immune system reacts much more quickly. In allergy, this mechanism is called "priming". You do not experience an allergic reaction the first time you are exposed to a particular allergen, but your body registers the allergen and, over time, you may develop an allergy to it.

Challenge test
See Provocation test

Corticosteroid drugs

Cell line
A general term applied to a defined population of cells that has been maintained in culture for an extended period and usually has undergone a spontaneous process, called transformation, that allows the cells to continue dividing (replicating) in culture indefinitely.

Comparative genomic hybridization (CGH)
A chromosomal screening technique that permits the detection of quantitative changes in chromosomal copy number without the need for cell culturing. It provides a global overview of chromosomal gains and losses throughout the whole genome (including extra, missing, and broken chromosomes), but cannot detect small changes in DNA sequence or changes in the imprinting state of a gene.

Chimera
An organism composed of cells derived from at least two genetically different individuals.

Chorion
The outermost of the two membranes surrounding the embryo/fetus, part of which forms the fetal portion of the placenta.

Cleavage
The process of cell division in the very early embryo before it becomes a blastocyst.

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