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Consanguinity
Consanguinity Having a common ancestor, ie, being blood relatives. Mating between two first cousins, for example, can be termed a consanguineous mating and is indicated in a pedigree by a double bar between the two parents. Such mating can result in an increased frequency of offspring who are *homozygous* for a recessive autosomal trait possessed by both parents, eg cystic fibrosis.
RELATED TERMS--------------------------------------
Ancestor An ancestor is a parent or (recursively) the parent of an ancestor. So this includes a father or mother, as well as grandparents, great-grandparents, and so on.
Blood The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.
Autosomal "Pertaining to a chromosome that is not a sex chromosome; relating to any one of the chromosomes save the sex chromosomes. People normally have 22 pairs of autosomes (44 autosomes) in each cell together with two sex chromosomes (X and Y in the male and XX in the female). "
Fibrosis The presence of scar tissue or collagen fibers in any tissue. In the liver, fibrosis or scarring of the liver damages the architecture and thus the functionality of the organ. Fibrosis, combined with the liver’s ability to regenerate, causes cirrhosis (regeneration within the scar tissue).
SIMILAR TERMS--------------------------------------
Conscious Mentally awake and aware. Knowing what one is doing and why.
Conservative mutation A change in a DNA or RNA sequence that leads to the replacement of one amino acid with a biochemically similar one. It is conservative in the sense that it is not a radical change that might, for example, stop all protein production.
Conservator An individual appointed by the court as guardian when a parent can't take care of his or her own child.
Conserved sequence A base sequence in a DNA molecule (or an amino acid sequence in a protein) that has remained essentially unchanged, and so has been conserved, throughout evolution.
Consolidation therapy Cancer treatment given after induction therapy to consolidate the gains obtained, further reduce the number of cancer cells and achieve a complete remission. Often just called consolidation. The overall sequence of therapy may be induction, consolidation, and maintenance therapy. Induction therapy is the initial step toward reducing the number of cancer cells. Consolidation is designed to further diminish the number of cancer cells and achieve a complete remission. Maintenance is given to maintain the remission and prevent a relapse.
Consorci Sanitari de Mataro Consorci Sanitari de Mataro is a hospital in Mataro, Catalonia (Spain).
Constant region The invariant carboxyl-terminal portion of an antibody molecule, as distinct from the variable region which is at the amino-terminal of the chain.
Constanta doctors All doctors near Constanta, Romania. Doctors who can assist a patient in Constanta.
Constantiaberg The Constantiaberg is a hospital in Cape Town, South Africa.
Constantine doctors All doctors near Constantine, Algeria. Doctors who can assist a patient in Constantine.
Constilac Constilac is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): lactulose.
Constipation Infrequent or difficult evacuation of feces.
Constraint-induced movement therapy A form of intensive physical therapy aimed at reorganizing and reprogramming the brain after a stroke, a traumatic brain injury, or spinal cord damage.
Constricted affect Affect type that represents mild reduction in the range and intensity of emotional expression.
Constrictive Pericarditis The pericardium is the sac around the heart. In some patients, this sac can become inflamed and scarred. If this scarring process produces a contracture or shrinkage of the pericardium, it can prevent the heart from filling to its full extent. This disease is known as constrictive pericarditis.
Constructional apraxia An acquired difficulty in drawing two-dimensional objects or forms, or in producing or copying three-dimensional arrangements of forms or shapes.
Constulose Constulose is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): lactulose.
Consultant An individual to whom one refers for expert advice or services. The use of consultants is common in medicine.
Consumption "1. Using up. 2. Wasting of the body; especially used in reference to advanced tuberculosis."
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Cell Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.
Chromosome A structural unit within a eukaryotic nucleus that carries genes. A chromosome consists of a long, continuous strand of DNA and associated proteins.
Cytoplasm The living matter within a cell (excluding the nucleus) that is responsible for the function of the cell (for example, protein synthesis).
Clotting The sealing of a blood vessel with coagulated blood.
Cardiac Pertaining to the heart.
Consanguinity
COX-2 inhibitor A nonsteroidal anti-inflammatory drug (NSAID) that specifically inhibits an enzyme known as cyclooxygenase-2 (COX-2). These drugs are used to treat pain and may be less likely to cause gastrointestinal bleeding than other NSAIDs.
COX-2 Cyclooxygenase-2.
Cyclooxygenase An enzyme that is responsible for formation of important biological mediators called prostanoids (including prostaglandins, prostacyclin and thromboxane). Pharmacological inhibition of COX can provide relief from the symptoms of inflammation and pain. This is the method of action of well-known drugs such as aspirin and ibuprofen.
Cytosine One of the pyrimidine nitrogenous bases occurring in both DNA and RNA.
Corticotropin-Releasing Hormone (CRH) The hormone released from the hypothalamus. It interacts with the pituitary to produce ACTH. This hormone uses cyclic AMP for its second messenger.
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