Conn syndrome
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  Conn syndrome



Conn syndrome

   Overproduction of the hormone aldosterone (pronounced al-do-ster-one) by a tumor that contains tissue resembling that normally present in the outer portion (cortex) of the adrenal gland. The excess aldosterone results in a potassium level (hypokalemia), underacidity of the body (alkalosis), muscle weakness, excessive thirst (polydipsia), excessive urination (polyuria), and high blood pressure (hypertension).

RELATED TERMS
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Hormone
A chemical substance formed in the body that is carried in the bloodstream to affect another part of the body; an example is thyroid hormone, produced by the thyroid gland in the neck, which affects growth, temperature regulation, metabolic rate, and other body functions.

Aldosterone
A hormone secreted by the adrenal cortex which affects blood pressure and saline balance.

Tumor
Overgrowth of tissue.

Tissue
Biological tissue is a group of cells that perform a similar function.The study of tissues is known as histology, or, in connection with disease, histopathology.The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope, though developments in electron microscopy, immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of decades.

Gland
An organ that releases a chemical. Endocrine glands are ductless and secrete hormones directly into the bloodstream. Exocrine glands secrete externally, either through a tube or duct.

Muscle
Tissue made up of bundles of long, slender cells that contract when stimulated.

Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.



SIMILAR TERMS
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Connecticut Children's Medical Center
Connecticut Children's Medical Center is a hospital in Hartford, Connecticut (USA).

Connectionism
A theory of information processing within cognitive science (the study of the mind). Connectionism is based upon the known neurophysiology of the brain.

Connective tissue
Fibrous tissue with a wide variety of connecting and supporting functions within and between body organs.

Connective tissue disease
Connective tissue diseases are inflammatory multisystem diseases characterised by evidence of autoimmunity (e.g. antibodies to cellular components) in which there are often prominent signs of involvement of the joints and other parts of the locomotor system. e.g. SLE.

Connective Tissue Disease
Disease caused by problem with collagen (the elastic support system in the body); can have a vascular component. Examples include Systemic Lupus Erythematosus (SLE), rheumatoid arthritis (RA). Can also be referred to mixed connective tissue diseases (MCTD)

Conner Williams Nursing Home
The Conner Williams Nursing Home is a hospital in Ridley Park, Pennsylvania, United States.

Connexin
A subunit of connexon, a protein that forms a gap junction, a channel that permits ions and small molecules to move between adjacent cells. The connexins are important to intercellular communication.

Connexon
"A special type of protein composed of an assembly of six subunits that are called connexins. A connexon of one cell is joined to that of an adjacent cell to form an intercellular channel consisting of 12 connexin subunits. Clusters of intercellular channels are known as a gap junction because of the minute extracellular ""gap"" that separates the apposed plasma membranes. Each intercellular channel provides an axial channel that interconnects the cytoplasm of the apposed cell directly and permits the passage of ion and other small molecules between adjacent cells."



PREVIOUS AND NEXT TERMS
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Conjoined twin
Identical (monozygotic) twins that did not separate fully from one another but are still partially united. Due to the incomplete division of one fertilized ovum.

Conjugated linoleic acid
(CLA) A supplement that has been promoted as an aid to weight loss and muscle building and as a deterrent to heart disease, diabetes and cancer. CLA is an unsaturated fatty acid in the milk and meat of cows, sheep and goats. CLA occurs in about 20 different chemical configurations called isomers, each tending to have different effects on the body. Knowledge of the benefits and risks of CLA is generally considered to be too rudimentary to warrant its use as a dietary supplement.

Conjunctival
Pertaining to the conjunctiva, the clear moist membrane that covers the inner surfaces of the eyelids and the front of eyeball.

Conjunctival fornix
The fornix of the conjunctivae refers to loose arching folds connecting the conjunctival membrane lining the inside of the eyelid with the conjunctival membrane covering the eyeball.

Conjunctivitis, allergic
Inflammation of the whites of the eyes (the conjunctivae) with itching and redness of the eyes and tearing, due to allergy. Frequently accompanies hay fever.

Conn syndrome

Connectionism
A theory of information processing within cognitive science (the study of the mind). Connectionism is based upon the known neurophysiology of the brain.

Connexin
A subunit of connexon, a protein that forms a gap junction, a channel that permits ions and small molecules to move between adjacent cells. The connexins are important to intercellular communication.

Connexon
"A special type of protein composed of an assembly of six subunits that are called connexins. A connexon of one cell is joined to that of an adjacent cell to form an intercellular channel consisting of 12 connexin subunits. Clusters of intercellular channels are known as a gap junction because of the minute extracellular ""gap"" that separates the apposed plasma membranes. Each intercellular channel provides an axial channel that interconnects the cytoplasm of the apposed cell directly and permits the passage of ion and other small molecules between adjacent cells."

Conotoxin
A toxin made by cone snails (Conidae), also called cone shells, which are fish-eating snails that inhabit tropical coral reefs, mangroves and associated habitats. Each of the 500 species of cone snail produces roughly 50 to 100 distinct conotoxins which they use to immobilize prey. These toxins are selective in their receptor binding sites. Conotoxins have been used to characterize receptors in heart muscle, skeletal muscle and brain. Calcium, potassium, and sodium ion channels have also been characterized using conotoxins.

Conservative mutation
A change in a DNA or RNA sequence that leads to the replacement of one amino acid with a biochemically similar one. It is conservative in the sense that it is not a radical change that might, for example, stop all protein production.

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