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Clone
Clone 1) An exact genetic replica of a DNA molecule, cell, tissue, organ, or entire plant or animal. 2) An organism that has the same nuclear genome as another organism.
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Genetic
Hereditary. Having to do with the genes.
Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.
Tissue
Biological tissue is a group of cells that perform a similar function.The study of tissues is known as histology, or, in connection with disease, histopathology.The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope, though developments in electron microscopy, immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of decades.
Organ
A structural unit of an animal or plant that serves a specific function.
Organism
A living thing, such as an animal, a plant, a bacterium, or a fungus.
Genome
The complete genetic material of an organism.
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Clonal deletion
The loss of lymphocytes of a particular specificity due to contact with either "self" or artificially introduced antigen.
Clonal selection theory
The prevalent concept that specificity and diversity of an immune response are the result of selection by antigen of specifically reactive clones from a large repertoire of preformed lymphocytes, each with individual specificities.
Clonazepam
An anticonvulsant.
Clone bank
Synonym for Genomic library.
Clones, recombinant
Clones containing recombinant DNA molecules.
Clonic seizure
A seizure in which there are generalized clonic contractions with the entire body jerking, but without a preceding tonic phase.
Clonidine hcl
Clonidine hcl is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): clonidine hydrochloride.
Clonidine hcl and chlorthalidone
Clonidine hcl and chlorthalidone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): chlorthalidone; clonidine hydrochloride.
Cloning
The production of a clone. (For the purpose of this report, generating an individual animal or person that derives its nuclear genes from a diploid cell taken from an embryo, fetus, or born individual of the same species.)
Cloning, cell
The process of producing a group of cells (clones), all genetically identical, from a single ancestor.
Cloning, DNA
The use of DNA manipulation procedures to produce multiple copies of a single gene or segment of DNA.
Clonote
The first cell produced by the combination of a nucleus and an enucleated ovum that launches the process of somatic-cell nuclear transfer (SCNT). As opposed to the zygote, the first cell resulting from fertilization.
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Comparative genomic hybridization (CGH)
A chromosomal screening technique that permits the detection of quantitative changes in chromosomal copy number without the need for cell culturing. It provides a global overview of chromosomal gains and losses throughout the whole genome (including extra, missing, and broken chromosomes), but cannot detect small changes in DNA sequence or changes in the imprinting state of a gene.
Chimera
An organism composed of cells derived from at least two genetically different individuals.
Chorion
The outermost of the two membranes surrounding the embryo/fetus, part of which forms the fetal portion of the placenta.
Cleavage
The process of cell division in the very early embryo before it becomes a blastocyst.
Cleavage pattern
The pattern in which cells in a very early embryo divide; each species of organism displays a characteristic cleavage pattern that can be observed under a microscope. Departure from the characteristic pattern usually indicates that an embryo is abnormal, so cleavage pattern is used as a criterion for preimplantation screening of embryos.
Clone
Cloning
The production of a clone. (For the purpose of this report, generating an individual animal or person that derives its nuclear genes from a diploid cell taken from an embryo, fetus, or born individual of the same species.)
Culture
Growth of cells, tissues or embryos in vitro on an artificial nutrient medium in the laboratory.
Cafe au lait spots
Irregularly shaped, permanent tan or light brown flat birthmark patches. More than a few large spots may indicate neurofibromatosis, a genetic disorder, so if your baby has them, tell his doctor.
Celiac sprue
An inherited food intolerance characterized by sensitivity to gluten, a protein found in wheat, rye, oats, and barley.
Cephalopelvic disproportion
When a baby's head is too large to pass through the mother's pelvis. This condition accounts for about 5 percent of cesarean deliveries.
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