Cinacalcet
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  Cinacalcet



Cinacalcet

   A drug that acts as a calcimimetic and that is marketed under the trade name Sensipar.

RELATED TERMS
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Calcimimetic
A drug in a class of orally active, small molecules that decrease the secretion of parathyroid hormone (PTH) by activating calcium receptors. The secretion of PTH is normally regulated by the calcium-sensing receptor. Calcimimetic agents increase the sensitivity of this receptor to calcium, which inhibits the release of parathyroid hormone and lowers parathyroid hormone levels within a few hours.

Sensipar
Sensipar is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cinacalcet hydrochloride.



SIMILAR TERMS
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Ciguatoxin
A seafood toxin that is acquired by eating fish that have consumed toxic single-celled marine organisms called dinoflagellates or fish that have consumed other fish that have become toxic. When someone eats these fish, they suffer seafood poisoning. Food poisoning from ciguatoxin is called ciguatera.

Ciliary body
Part of the eye, the ciliary body is a thin vascular (blood vessel-filled) middle layer of the eye that is situated between the sclera (the white of the eye) and the retina (the nerve layer that lines the back of the eye, senses light, and creates impulses that travel through the optic nerve to the brain).

Ciliary muscle
One of the muscles that relax the zonules to enable the lens to change shape for focusing. The zonules are fibers that hold the lens suspended in position and enable it to change shape during accommodation.

Ciliary neuralgia
A distinctive syndrome of headaches, better known today as cluster headache.

Cilium
A fine hairlike projection from a cell such as those in the respiratory tract. Cilia can help to sweep away fluids and particles. Some single-celled organisms use the rhythmical motion of cilia for locomotion.

Cinacalcet

Circle of Willis
An arterial circle at the base of the brain that is of critical importance. The circle of Willis receives all the blood that is pumped up the two internal carotid arteries that come up the front of the neck and that is pumped from the basilar artery formed by the union of the two vertebral arteries that come up the back of the neck. All the principal arteries that supply cerebral hemispheres of the brain branch off from the circle of Willis.

Circular breathing
Inhaling through the nose and inflating the cheeks and neck with air at the same time.Some saxophone players do circular breathing; this may not be a safe practice since it may reduce blood flow to the brain.

Circulation, fetal
The blood circulation in the fetus (the unborn baby). Before birth, the blood from the heart that is destined (in the pulmonary artery) for the lungs is shunted away from the lungs and returned to the greatest of arteries (the aorta). The shunt is through a short vessel called the ductus arteriosus. When this shunt is open, it is said to be a patent (pronounced pá tent) ductus arteriosus (PDA). The PDA usually closes at or shortly after birth and blood is permitted to course freely to the lungs.

Circulatory
Having to do with the circulation, the movement of fluid in a regular or circuitous course. Although the adjective "circulatory" need not necessarily refer to the circulation of the blood, for all practical purposes today it does. A circulatory problem is taken usually to be a problem with the blood circulation, for example with heart failure.

Circum-
Prefix meaning around, surrounding, or encircling. As in circumcision, circumflex, and circumjacent. From the Latin preposition circum meaning round.

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