Change, single base
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   Change, single base


Change, single base

   A change in which a single base in the DNA differs from the usual base at that position. These single base changes are also called SNPs or "snips."

RELATED TERMS
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Base
A chemical compound that either donates hydroxide ions or absorbs hydrogen ions when dissolved in water. Bases and acids are referred to as opposites because the effect of an acid is to increase the hydronium ion concentration in water, whereas bases reduce this concentration. Arrhenius bases are water-soluble and always have a pH greater than 7 in solution.



SIMILAR TERMS
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Chancre
The painless ulcer of primary syphilis that appears on the genitals.

Chancroid
A sexually transmitted disease that causes soft, painful open sores in the genital area. Not syphilis. Characterized by swelling of the sebaceous glands, resulting in pimples on the face, back and chest.

Chandan Nagar doctors
All doctors near Chandan Nagar, India. Doctors who can assist a patient in Chandan Nagar.

Chandigarh doctors
All doctors near Chandigarh, India. Doctors who can assist a patient in Chandigarh.

Chandipura virus
A virus that causes fever, symptoms similar to those of flu, and acute encephalitis (inflammation of the brain).

Chandler doctors
All doctors near Chandler, the United States of America. Doctors who can assist a patient in Chandler.

Chandrapur doctors
All doctors near Chandrapur, India. Doctors who can assist a patient in Chandrapur.

Changchun doctors
All doctors near Changchun, China. Doctors who can assist a patient in Changchun.

Changde doctors
All doctors near Changde, China. Doctors who can assist a patient in Changde.

Changi General Hospital
The Changi General Hospital is a hospital in Singapore.

Changji doctors
All doctors near Changji, China. Doctors who can assist a patient in Changji.

Changsha doctors
All doctors near Changsha, China. Doctors who can assist a patient in Changsha.

Changweon doctors
All doctors near Changweon, South Korea. Doctors who can assist a patient in Changweon.

Changzhi doctors
All doctors near Changzhi, China. Doctors who can assist a patient in Changzhi.

Changzhou doctors
All doctors near Changzhou, China. Doctors who can assist a patient in Changzhou.

Channelopathy
A disease involving dysfunction of an ion channel. Channelopathies are known that involve the ion channels for potassium, sodium, chloride and calcium. There are also channelopathies involving the acetylcholine receptor, the glycine receptor, and other receptors. Each channelopathy can play a role in a number of different diseases. For example, the calcium channelopathies include familial hemiplegic migraine, malignant hyperthermia (a rare but often fatal genetic condition during anesthesia), episodic ataxia type 2, spinocerebellar ataxia type 6, hypokalemic periodic paralysis type I, central core disease (a cause of the floppy baby syndrome), congenital night blindness and stationary night blindness.



PREVIOUS AND NEXT TERMS
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Chain-termination codon
A set of three adjacent bases in the DNA or their complementary bases in messenger RNA that specifies the end of a polypeptide chain.

Chamber, anterior
The space in the eye that is behind the cornea and in front of the iris.

Chamber, posterior
The space in the eye behind the iris and in front of the lens. The iris is the colored ring of tissue that regulates the amount of light entering the eye by adjusting the size of the pupil. The lens is the transparent biconvex body in the eye that refracts light.

Chamomile
An herb often used in the form of a tea as a sedative.

Chandipura virus
A virus that causes fever, symptoms similar to those of flu, and acute encephalitis (inflammation of the brain).

Change, single base

Channelopathy
A disease involving dysfunction of an ion channel. Channelopathies are known that involve the ion channels for potassium, sodium, chloride and calcium. There are also channelopathies involving the acetylcholine receptor, the glycine receptor, and other receptors. Each channelopathy can play a role in a number of different diseases. For example, the calcium channelopathies include familial hemiplegic migraine, malignant hyperthermia (a rare but often fatal genetic condition during anesthesia), episodic ataxia type 2, spinocerebellar ataxia type 6, hypokalemic periodic paralysis type I, central core disease (a cause of the floppy baby syndrome), congenital night blindness and stationary night blindness.

Chaperone
Any protein that is required for the proper folding or assembly of another protein or protein complex without being a component of the final structure.

Chapped lips
Dry, cracked or sore lips, usually in cold, windy, dry weather and less often in warm weather. Sun exposure can contribute to chapping of the lips. Licking or biting the lips does not help the situation.

Char syndrome
A genetic disorder characterized by patent ductus arteriosis and unusual facial features including a long philtrum (increase in the distance between the nose and upper lip), down-slanting palpebral fissures (eye slits), and thick lips as well as incurving fifth fingers.

Charbon
Known also as anthrax, charbon is a serious bacterial infection. It is not primarily a human disease but rather an infection of animals. Cattle, sheep, horses, mules, and some wild animals are highly susceptible. Humans (and swine) are generally resistant to anthrax. Anthrax can take different forms. With the lung form of the disease. People inhale the anthrax spores and, if untreated, are likely to die. An intestinal form is caused by eating meat contaminated with anthrax. But most human anthrax comes from skin contact with animal products. Cutaneous (skin) anthrax was once well known among people who handled infected animals, like farmers, woolsorters, tanners, brushmakers and carpetmakers in the days when the brushes and carpets were animal products. The hallmark of skin anthrax is a carbuncle, a cluster of boils, that ulcerates in an ugly way. Typically this lesion has a hard black center surrounded by bright red inflammation.

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