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Bulla
Bulla A large blister appearing as a circumscribed area of separation of the epidermis from the subepidermal structure (subepidermal bulla) or as a circumscribed area of separation of epidermal cells (intraepidermal bulla) caused by the presence of serum, or occasionally by an injected substance.
RELATED TERMS--------------------------------------
Blister
Buildup of watery or bloody fluid under the skin.
Circumscribed
Having a border, localized. Often associated with a capsule and benign tumors of the brain, for example, meningiomas, pituitary adenomas and acoustic neuromas. See diffuse.
Epidermis
The outermost layer of skin.
Epidermal
Pertaining to the epidermis, the outermost layer of the skin.
Serum
The fluid portion of the blood. It is essentially similar in composition to plasma but lacks fibrinogen and other substances that are used in the coagulation (blood clotting) process.
SIMILAR TERMS--------------------------------------
Bullae
More than one bulla, a bulla being a blister more than 5 mm (about 3/16 inch) in diameter with thin walls that is full of fluid.
Buller Hospital
The Buller Hospital is a hospital in West Coast, New Zealand.
Bulli Hospital
The Bulli Hospital is a hospital in Bulli, New South Wales, Australia.
Bullous
Characterized by blistering, such as in a second-degree burn.
Bullous pemphigoid
A disease characterized by tense blisters on the skin. The condition is caused by antibodies that accumulate abnormally in a layer of the skin called the basement membrane. The antigen of this autoimmune disease is localized to the hemidesmosome. Most cases of the disease are in older people but the disease can affect younger people, even babies. Bullous pemphigoid can be chronic, mild and not affect the general health or it can be severe and compromise the health of the sufferer. The diagnosis can be confirmed by a skin biopsy showing the abnormal antibodies deposited in the skin layer. Treatment is with topical cortisone creams, but especially severe cases may sometimes require high doses of cortisone-like drugs (steroids) or immune suppression drugs, such as azathoprine (Imuran).
PREVIOUS AND NEXT TERMS--------------------------------------
Blinded medications
Products that appear identical in size, shape, colour, flavour, and other attributes to make it very difficult for subjects and investigators to determine which medication is being administered.
Blind study
One in which the subject or the investigator (or both) are unaware of what trial product a subject is taking. See also double-blind study, single-blind study, triple-blind study.
Blinding/masking
A procedure in which one or more parties to the trial are kept unaware of the treatment assignments. Single-blinding usually refers to the subject(s) being unaware, and doubleblinding usually refers to the subject(s), investigators, monitor, and, in some cases, data analyst(s) being unaware of the treatment assignments.
Blood agar
A mixture of blood and nutrient agar, used for the cultivation of many medically important microorganisms.
Brucella
A genus of encapsulated, nonmotile bacteria (family Brucellaceae) containing short, rod-shaped to coccoid, Gram-negative cells. These organisms are parasitic, invading all animal tissues and causing infection of the genital organs, the mammary gland, and the respiratory and intestinal tracts, and are pathogenic for man and various species of domestic animals. They do not produce gas from carbohydrates.
Bulla
Butchart staging system
The staging system most often used for mesothelioma. It is divided into Stages I - IV with the levels determined by the tissue involved.
Balneotherapy
The treatment of illness by baths (e.g., mud baths).
Bioactive
Chemically affecting a living being.
Bulimia (binge-eating syndrome, bulimarexia, bulimia nervosa, BN)
That eating disorder characterized by recurrent binge eating; recurrent willful vomiting and/or other recurrent inappropriate compensatory measures to prevent weight gain (e.g., laxative abuse, diuretic abuse, or overexercising); and an excessive influence of body weight or shape on self-evaluation.
Background Retinopathy
Early stage of diabetic retinopathy; usually does not impair vision. Also called "nonproliferative retinopathy."
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