Brittle bone disease
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  Brittle bone disease



Brittle bone disease

   Osteogenesis imperfecta, not one but a group of genetic diseases, all of which affect collagen, a key component of connective tissue in tissues like bone, tendon and skin. All types of osteogenesis imperfecta result in fragile bones.

RELATED TERMS
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Genetic
Hereditary. Having to do with the genes.

Diseases
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Affect
This word is used to described observable behavior that represents the expression of a subjectively experienced feeling state (emotion). Common examples of affect are sadness, fear, joy, and anger. The normal range of expressed affect varies considerably between different cultures and even within the same culture. Types of affect include: euthymic, irritable, constricted; blunted; flat; inappropriate, and labile.

Collagen
At a microscopic level, this is the 'skeleton' of most tissues in the body.

Tissue
Biological tissue is a group of cells that perform a similar function.The study of tissues is known as histology, or, in connection with disease, histopathology.The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope, though developments in electron microscopy, immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of decades.

Bone
Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.

Tendon
Band of fibrous tissue by which muscle is attached to bone.

Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).



SIMILAR TERMS
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British doctor
A doctor who, being or not a citizen of that country, has been admitted to practice medicine in Great Britain.

British empiricism
Rejects the notion that ideas were implanted in the mind at birth. Instead all complex ideas are built up for the sense organs. Ultimately all knowledge is achieved by associating simple sensations.

Brittle Diabetes
Diabetes that is very difficult to control. It is an antiquated term that has no place in current management of diabetes. In particular it is not a distinct form of diabetes, and usually will respond to a more intensive team approach to care.



PREVIOUS AND NEXT TERMS
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Breastfeeding practices
The practices to be followed in breastfeeding a baby. Human milk is the preferred feeding for all infants, including premature and sick newborns, with rare exceptions. When direct breastfeeding is not possible, expressed human milk, fortified when necessary for the premature infant, should be provided. The following recommendations are based on those of the American Academy of Pediatrics.

Breathing
The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.

Breech
The buttocks.

Breslow thickness
A method for determining the prognosis with melanoma. The thickness of a melanoma is related to the 5-year survival rate after surgical removal of the tumor.

Brill-Zinsser disease
Recrudescence of epidemic typhus years after the initial attack. The agent that causes epidemic typhus (Rickettsia prowazekii) remains viable for many years and then when host defenses are down, it is reactivated causing recurrent typhus. The disease is named for the physician Nathan Brill and the great bacteriologist Hans Zinsser.

Brittle bone disease

Broken hip
Fractured bone in the hip, a key health problem among the elderly, usually due to a fall or other kind of trauma involving direct impact to the hip bone which has been weakened by osteoporosis. The part of the hip most often broken is the greater trochanter of the femur.

Bromism
A disease caused by chronic exposure to bromine or one of its compounds. Bromism is characterized by mental dullness, memory loss, slurred speech, tremors, ataxia and muscular weakness, a transitory state resembling paranoid schizophrenia, and a skin eruption (bromoderma). Once a common problem, bromism was generally due to chronic ingestion of proprietary bromide preparations. Also called brominism.

Bromobenzylcyanide
"A riot control agent or ""tear gas."""

Bromoderma
A skin eruption brought on by chronic exposure to bromine. Essentially an allergic reaction to bromine. There are diverse sources of bromine exposure including brominated vegetable oil, a commonly used emulsifier and flavor carrier in food products. Bromoderma is a form of bromism.

Bronchiole
A tiny tube in the air conduit system within the lungs that is a continuation of the bronchi and connects to the alveoli (the air sacs) where oxygen exchange occurs. Bronchiole is the diminutive of bronchus, from the word bronchos by which the Greeks referred to the conduits to the lungs.

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