Annotation
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  Annotation



Annotation

   In genetics, the process of identifying the locations and coding regions of genes in a genome and determining what those genes do. To annotate (irrespective of the context) is to add a note by way of explanation or commentary. Once a genome is sequenced, it needs to be annotated to make sense of it.

RELATED TERMS
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Genetics
The scientific study of heredity. Genetics pertains to humans and all other organisms. So, for example, there is human genetics, mouse genetics, fruitfly genetics, etc.

Genes
Basic, functional units of heredity, each occupying a specific place on a chromosome.

Genome
The complete genetic material of an organism.

Annotate
In genetics, to identify the locations and the coding regions of genes in a genome and determine what those genes do. To annotate (irrespective of the context) is to add a note by way of explanation or commentary. Once a genome is sequenced, it needs to be annotated to make sense of it.



SIMILAR TERMS
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Annotate
In genetics, to identify the locations and the coding regions of genes in a genome and determine what those genes do. To annotate (irrespective of the context) is to add a note by way of explanation or commentary. Once a genome is sequenced, it needs to be annotated to make sense of it.

Annotation, genome
The process of identifying the locations and the coding regions of genes in a genome and determining what those genes do. An annotation (irrespective of the context) is a note added by way of explanation or commentary. Once a genome is sequenced, it needs to be annotated to make sense of it.

Annotto Bay Hospital
The Annotto Bay Hospital is a hospital in St Mary, Jamaica.



PREVIOUS AND NEXT TERMS
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Annals of Internal Medicine
"A medical journal especially concerned with information in the field of internal medicine (adult medicine). Designed to be read largely by internists, the Annals states it is ""is the leading journal for studies in internal medicine."

Annexin A1
One of the annexins, a family of proteins that share the property of binding calcium and phospholipids. The gene for annexin A1 (ANXA1) is upregulated in hairy cell leukemia. ANXA1 protein expression is specific to hairy cell leukemia. Detection of ANXA1 (by immunocytochemical means) reportedly provides a simple, highly sensitive and specific assay for the diagnosis of hairy cell leukemia.

Annexin V
Annexin V is the cause of a syndrome called the antiphospholipid antibody syndrome with abnormal blood clotting.

Annexins
The annexins are a family of proteins first described in 1990. All of the annexin proteins share the property of binding calcium and phospholipids. The antiphospholipid antibody syndrome is due to a deficiency of annexin V. Annexin V normally forms a shield around certain phospholipid molecules that blocks their entry into coagulation (clotting) reactions. In the antiphospholipid antibody syndrome, the formation of this shield is disrupted by the abnormal antibodies. Without the shield, there is an increased quantity of phospholipid molecules on cell membranes, speeding up coagulation reactions and causing the abnormal blood clotting characteristic of the antiphospholipid antibody syndrome. See also: Annexin A1.

Annotate
In genetics, to identify the locations and the coding regions of genes in a genome and determine what those genes do. To annotate (irrespective of the context) is to add a note by way of explanation or commentary. Once a genome is sequenced, it needs to be annotated to make sense of it.

Annotation

Annotation, genome
The process of identifying the locations and the coding regions of genes in a genome and determining what those genes do. An annotation (irrespective of the context) is a note added by way of explanation or commentary. Once a genome is sequenced, it needs to be annotated to make sense of it.

Annular pancreas
"An abnormal ring of pancreas that encircles the duodenum and often causes intestinal obstruction. Nausea and vomiting are the usual symptoms and reflect the intestinal obstruction. Complete obstruction is usually evident in the newborn period. Partial obstruction may not present until later in childhood or adulthood. Diagnostic tests include upper GI series, abdominal CT scan, and endoscopy. The treatment is surgical. Complications include peptic ulcer disease and perforation of the intestine. ""Annular"" is the adjective for ""annulus"" (a little ring)."

Anomalad, Klippel-Feil
See: Klippel-Feil sequence.

Anomaly, congenital
A birth defect. A malformation that occurs before birth and is present at birth.

Anomaly, Klippel-Feil
See: Klippel-Feil sequence.

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