Adult-onset Still disease

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Adult-onset Still disease

Adult-onset Still disease

"Although Still disease was first described in children, it is known to begin in adults (rarely). Of all patients with Still disease, 100% have high intermittent fever; 100% have joint inflammation and pain, muscle pain with fevers, and develop persistent chronic arthritis. Ninety-five percent (95%) have the faint salmon-colored skin rash. Eighty-five percent (85%) have swelling of the lymph glands or enlargement of the spleen and liver; and 85% have a marked increase in the white blood cell count. Sixty percent (60%) have inflammation of the lungs (pleuritis) or around the heart (pericarditis). Forty percent (40%) have severe anemia. And twenty percent (20%) have abdominal pain. "

RELATED TERMS
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Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Fever
When body temperature rises above its normal level - defined as 98.6 degrees F, though it varies by individual and time of day. A fever is the sign of an immune system at work and usually indicates an infection.

Joint
Where the ends of two or more bones meet.

Inflammation
A reaction to an injury to the body - by infection, chemicals or physical agents. The symptoms can be - depending on the location of the injury- redness, swelling, heat and pain. The purpose of the inflammation is to dilute and destroy the agent causing the inflammation. To do this, the immune system starts a cascade of actions that causes active cells to gather at the affected location. It is these cells and fluids that cause the redness, swelling, heat and pain.

Pain
An unpleasant sensory or emotional experience primarily associated with tissue damage, or described in terms of tissue damage, or both.

Muscle
Tissue made up of bundles of long, slender cells that contract when stimulated.

Chronic
Ongoing or recurring. Chronic medical conditions include diabetes, epilepsy, and chronic fatigue syndrome.

Arthritis
Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. Arthritis occurs in various forms, such as the arthritis associated with infections, osteoarthritis, or rheumatoid arthritis. Many forms of vasculitis can also be associated with arthritis.

Faint
Temporary loss of consciousness because of an insufficient blood supply to the brain.

Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).

Rash
A reddish spot or patch of irritated skin. Rashes can be caused byillnesses, allergies, and heat and are usually temporary.

Lymph
Consists primarily of a clear, yellowish fluid and white blood cells. Found in the lymphatic system.

Spleen
The organ that cleans blood and makes white blood cells.

Liver
The largest organ in the body. The liver carries out many important functions, such as making bile, changing food into energy, and cleaning alcohol and poisons from the blood.

Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.

Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.

Lungs
The main respiratory organs in the chest where blood is oxygenated.

Heart
The hollow, muscular organ responsible for pumping blood through the circulatory system.

Anemia
Anemia is a condition in which a deficiency in the size or number of erythrocytes (red blood cells) or the amount of hemoglobin they contain limits the exchange of oxygen and carbon dioxide between the blood and the tissue cells. Most anemias are caused by a lack of nutrients required for normal erythrocyte synthesis, principally iron, vitamin B-12, and folic acid. Others result from a variety of conditions, such as hemorrhage, genetic abnormalities, chronic disease states or drug toxicity.

Abdominal
Relating to the abdomen, the belly, that part of the body that contains all of the structures between the chest and the pelvis. The abdomen is separated anatomically from the chest by the diaphragm, the powerful muscle spanning the body cavity below the lungs. The abdomen includes a host of organs including the stomach, small intestine, colon, rectum, liver, spleen, pancreas, kidneys, appendix, gallbladder, and bladder. The word "abdomen" has a curious story behind it. It comes from the Latin "abdodere", to hide. The idea was that whatever was eaten was hidden in the abdomen.

SIMILAR TERMS
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Adult acne
Popular name for rosacea. For more information, see: Rosacea.

Adult primary liver cancer
A tumor in which the cancer starts during adulthood in cells in the liver. Also called hepatocellular carcinoma. Primary liver cancer is different from cancer that has metastasized (spread) from another place in the body to the liver.

Adult respiratory distress syndrome
Better known as ARDS. See: ARDS.

Adult stem cell
An undifferentiated cell found in a differentiated tissue in an adult organism that can renew itself and can (with certain limitations) differentiate to yield all the specialized cell types of the tissue from which it originated.

Adult T-cell leukemia
"Abbreviated ATL. A malignancy of mature T lymphocytes (T cells) with its onset in adulthood caused by infection with the human T-lymphotropic virus (HTLV) and characterized by circulating malignant T-lymphocytes, skin lesions, lymphadenopathy (enlarged lymph nodes), hepatosplenomegaly (enlarged liver and spleen), hypercalcemia (high blood calcium), lytic (""punched out"") bone lesions, and a tendency to infection. There are four categories of ATL, based on the aggressiveness of the disease -- smoldering, chronic, lymphoma, and acute. The disease is also called adult T-cell leukemia/lymphoma and adult T-cell lymphoma. See also: Human T-lymphotropic virus."

Adult T-cell leukemia/lymphoma
See: Adult T-cell leukemia.

Adult T-cell lymphoma
See: Adult T-cell leukemia.

Adult-onset diabetes
Type 2 diabetes. See also Diabetes, type 2.

Adult-Onset Diabetes
Former term for Type 2 diabetes.

PREVIOUS AND NEXT TERMS
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Adult respiratory distress syndrome
Better known as ARDS. See: ARDS.

Adult T-cell leukemia
"Abbreviated ATL. A malignancy of mature T lymphocytes (T cells) with its onset in adulthood caused by infection with the human T-lymphotropic virus (HTLV) and characterized by circulating malignant T-lymphocytes, skin lesions, lymphadenopathy (enlarged lymph nodes), hepatosplenomegaly (enlarged liver and spleen), hypercalcemia (high blood calcium), lytic (""punched out"") bone lesions, and a tendency to infection. There are four categories of ATL, based on the aggressiveness of the disease -- smoldering, chronic, lymphoma, and acute. The disease is also called adult T-cell leukemia/lymphoma and adult T-cell lymphoma. See also: Human T-lymphotropic virus."

Adult T-cell leukemia/lymphoma
See: Adult T-cell leukemia.

Adult T-cell lymphoma
See: Adult T-cell leukemia.

Adult-onset diabetes
Type 2 diabetes. See also Diabetes, type 2.

Adult-onset Still disease

Advance grief
See: Anticipatory grief.

Advance medical directives
These directives pertain to treatment preferences and the designation of a surrogate decision-maker in the event that a person should become unable to make medical decisions on their own behalf. Advance directives generally fall into three categories: living will, power of attorney and health care proxy.

Advanced maternal age
Usually defined as age 35 or more for the mother at the time of delivery of her baby. Advanced maternal age predisposes to Down syndrome (trisomy 21). The risk of having a Down syndrome baby rises with maternal age. It essentially doubles from 1 in 725 at maternal age 32 to 1 in 365 at maternal age 35. And the risk continues to climb with the years and is 1 in 32 at maternal age 45.

Advanced paternal age
A man who is age 40 years or older at the time of conception. (There is no universally accepted definition of advanced paternal age but this criterion is often used in genetic counseling.)

Adventitia
"The outermost connective tissue covering of any organ, vessel, or other structure. For example, the connective tissue that surrounds an artery is called the adventitia because it is considered extraneous to the artery. ""Adventitia"" comes from the Latin ""adventicius"" meaning ""foreign, strange, extraneous, coming from abroad or from outside."" Other English words that stem from ""advenire"" include ""adventure"" and ""avenue."" A related term is ""adventititious"" meaning ""coming from an external source or occurring in an unusual place or manner."" When a doctor or nurse listens to the chest or abdomen, adventitious sounds are those that are normally not heard coming from the chest or abdomen."

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This dictionary contains 25007 terms.

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